TMX1 and GIMAP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMX1	GIMAP1
Description		thioredoxin related transmembrane protein 1	GTPase, IMAP family member 1
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GO Annotations	Cellular Component	Extracellular Region Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endomembrane System Membrane Mitochondrial Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane
	Molecular Function	Protein Disulfide Isomerase Activity Enzyme Inhibitor Activity Protein Binding Protein-disulfide Reductase Activity Disulfide Oxidoreductase Activity Isomerase Activity	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Negative Regulation Of Triglyceride Biosynthetic Process Triglyceride Biosynthetic Process Response To Endoplasmic Reticulum Stress Regulation Of Calcium Ion Transport Negative Regulation Of Platelet Aggregation Positive Regulation Of ERAD Pathway
Pathways
Drugs
Diseases
GWAS		Cancer ( 29299148) Nonsyndromic cleft lip with or without cleft palate ( 28087736) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576)
Interacting Genes		13 interacting genes: BCL2L2 CCR1 CDC42 DNAAF2 FAS FKBP8 GET3 GIMAP1 GIMAP5 LHFPL5 PMP22 SPI1 SULT2A1	40 interacting genes: AQP6 ARL13B BLCAP CD79A CLEC10A CPLX4 CREB3L1 EBP ELOVL4 ERGIC3 FAM174A FAM209A FCGR2A GJA8 GPX8 HSD17B11 IL3RA JAGN1 MGST3 PTGES REEP4 RMDN3 SCN3B SLC10A6 SLC14A1 SLC18A1 SLC71A2 STOM STX1A THAP4 TM4SF19 TMEM101 TMEM14B TMEM35A TMEM45B TMEM79 TMX1 TMX2 ZDHHC15 ZFYVE27
Entrez ID		81542	170575
HPRD ID		15590	16278
Ensembl ID		ENSG00000139921	ENSG00000213203
Uniprot IDs		Q9H3N1	A0A090N8Z4 Q8WWP7
PDB IDs		1X5E	3V70
Enriched GO Terms of Interacting Partners?			Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Glutathione Peroxidase Activity Protein Binding Disulfide Oxidoreductase Activity
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