POLR2M and WDR89

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		POLR2M	WDR89
Description		RNA polymerase II subunit M	WD repeat domain 89
Image			No pdb structure
GO Annotations	Cellular Component	DNA-directed RNA Polymerase Complex Nucleus Nuclear Envelope RNA Polymerase II, Core Complex I Band Neuronal Cell Body Transcription Preinitiation Complex
	Molecular Function	RNA Polymerase II Complex Binding Transcription Elongation Factor Activity
	Biological Process	Transcription Elongation By RNA Polymerase II Maintenance Of ER Location	Ventricular System Development Corpus Callosum Development
Pathways
Drugs
Diseases
GWAS		Body mass index ( 28552196) Seasonality ( 25562672)	Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)
Interacting Genes		22 interacting genes: AHSP ANKHD1 APOD CEBPG CEP126 DAPK1 DGKZ HIGD1B LRRK1 LRRK2 MYO3A MYO9A NEDD4 PSMC2 RBM4B RPL7A SCMH1 SIVA1 THAP1 UQCRQ WDR89 ZNF410	5 interacting genes: APP PHYHIP POLR2M POLR3F SOCS6
Entrez ID		81488	112840
HPRD ID		07575	12635
Ensembl ID		ENSG00000255529	ENSG00000140006
Uniprot IDs		P0CAP2 Q6EEV4	Q96FK6
PDB IDs		6DRD
Enriched GO Terms of Interacting Partners?			Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway DNA-directed RNA Polymerase Complex Maintenance Of ER Location Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Endoplasmic Reticulum Localization Heparan Sulfate Binding Signaling Receptor Activator Activity Transcription Elongation Factor Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel
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