COASY and RPS6KB2

Number of citations of the paper that reports this interaction (PubMedID 15589845)
0

Data Source:
HPRD (in vivo)

		COASY	RPS6KB2
Description		Coenzyme A synthase	ribosomal protein S6 kinase B2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Mitochondrial Matrix Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Nucleotide Binding Catalytic Activity Dephospho-CoA Kinase Activity Pantetheine-phosphate Adenylyltransferase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Nucleotidyltransferase Activity	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Ribosomal Protein S6 Kinase Activity ATP Binding Kinase Activity Transferase Activity Peptide Binding Protein Serine Kinase Activity
	Biological Process	Coenzyme A Biosynthetic Process	Cytoplasmic Translation Translation Signal Transduction TOR Signaling TORC1 Signaling Positive Regulation Of Translational Initiation Negative Regulation Of Insulin Receptor Signaling Pathway
Pathways		Coenzyme A biosynthesis	AKT phosphorylates targets in the nucleus Constitutive Signaling by AKT1 E17K in Cancer
Drugs
Diseases
GWAS		Medication use (drugs used in diabetes) ( 31015401) Metabolic syndrome ( 31589552)	Hip circumference adjusted for BMI ( 34021172) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		14 interacting genes: APP BTK CFTR CNTROB IFT20 KIAA1958 KRT20 LYN PJA1 POU3F2 RPS6KB1 RPS6KB2 SRC SYK	22 interacting genes: BTK CFTR COASY EEF2K EP300 FBXO25 FYN HNRNPA1 IKBKG KAT2B LRRK2 LYN MAPK8IP2 MTOR NEDD4L PDGFRB PDPK1 PRKCE RPS6 SRC SRPK1 SYK
Entrez ID		80347	6199
HPRD ID		13080	10203
Ensembl ID		ENSG00000068120	ENSG00000175634
Uniprot IDs		Q13057	Q9UBS0
PDB IDs
Enriched GO Terms of Interacting Partners?		Signaling Receptor Activator Activity Peptidyl-tyrosine Phosphorylation Non-membrane Spanning Protein Tyrosine Kinase Activity Fc Receptor Signaling Pathway TORC1 Signaling Phospholipase Binding Stimulatory C-type Lectin Receptor Signaling Pathway Cellular Response To Lectin TOR Signaling Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-epsilon Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Ephrin Receptor Binding Protein Kinase Activity Negative Regulation Of Inflammatory Response To Antigenic Stimulus Cellular Response To Oxygen-containing Compound Regulation Of Vesicle-mediated Transport Fc-gamma Receptor Signaling Pathway Protein Tyrosine Kinase Activity Cellular Response To Molecule Of Fungal Origin Integrin Binding Kinase Activity Histamine Secretion By Mast Cell Protein Phosphorylation Response To Molecule Of Fungal Origin Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Pattern Recognition Receptor Signaling Pathway Cellular Developmental Process Phosphorylation B Cell Receptor Signaling Pathway Positive Regulation Of Cell Activation Innate Immune Response-activating Signaling Pathway Histamine Secretion Regulation Of Inflammatory Response Regulation Of Innate Immune Response Glial Cell Development Activation Of Innate Immune Response Positive Regulation Of TORC1 Signaling Negative Regulation Of TORC1 Signaling Membrane Raft Response To Lipid Positive Regulation Of Defense Response Histamine Transport Cellular Response To Lipid Positive Regulation Of Protein Metabolic Process Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Scaffold Protein Binding Positive Regulation Of Developmental Process Phospholipase Activator Activity	Cellular Response To Oxygen-containing Compound Protein Phosphorylation Kinase Activity Protein Kinase Activity Phosphorylation Transferase Activity Positive Regulation Of Cellular Component Organization Protein Modification Process Phospholipase Binding Peptidyl-tyrosine Phosphorylation Stimulatory C-type Lectin Receptor Signaling Pathway Cellular Response To Lectin Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Signaling Pathway ATP Binding Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Protein Tyrosine Kinase Activity Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Cellular Response To Stress Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Activation Fc-gamma Receptor Signaling Pathway Phospholipase Activator Activity Protein Metabolic Process Phosphate-containing Compound Metabolic Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Nucleotide Binding Response To Hormone Regulation Of Innate Immune Response Innate Immune Response-activating Signaling Pathway Non-membrane Spanning Protein Tyrosine Kinase Activity Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Response To Peptide Hormone T Cell Costimulation Cytoplasm Response To Stress Activation Of Innate Immune Response Positive Regulation Of Lymphocyte Activation Regulation Of Transport Immune Response-activating Signaling Pathway Protein Autophosphorylation Positive Regulation Of Signal Transduction Regulation Of Vesicle-mediated Transport Positive Regulation Of Immune System Process Regulation Of Cellular Component Organization Transmembrane Transporter Binding Cellular Response To Nutrient Levels
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