WDR26 and HBP1

Number of citations of the paper that reports this interaction (PubMedID 34647674)
65

Data Source:
BioGRID (enzymatic study)

		WDR26	HBP1
Description		WD repeat domain 26	HMG-box transcription factor 1
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GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol GID Complex	Chromatin Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding RNA Binding Protein Binding
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Wnt Signaling Pathway Regulation Of Cell Cycle
Pathways		Regulation of pyruvate metabolism
Drugs
Diseases
GWAS		Basophil percentage of white cells ( 32888494) Major depressive disorder ( 21042317) Monocyte percentage of white cells ( 32888494) White blood cell count ( 27863252)	Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: DSCR9 HBP1 MAPK6	20 interacting genes: ANKRD2 CASP8 CD2AP CREBBP EP300 ESR1 EWSR1 HDAC1 KIFBP RB1 RB1CC1 RBL2 SAP30 SIN3A SMAD1 TCF4 TMEM37 UBE2H WDR26 ZNF212
Entrez ID		80232	26959
HPRD ID		18298	13634
Ensembl ID		ENSG00000162923	ENSG00000105856
Uniprot IDs		A0A499FIZ0 Q9H7D7	B4DJ36 O60381
PDB IDs		8QBN 8QE8	2E6O 3QVE
Enriched GO Terms of Interacting Partners?		Septin Cytoskeleton	Transcription Regulator Complex RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone H3K27 Acetyltransferase Activity Chromatin Cell Differentiation Sin3-type Complex Histone H3K18 Acetyltransferase Activity Transcription Corepressor Activity N-terminal Peptidyl-lysine Acetylation Regulation Of Transcription By RNA Polymerase II Peptide Lactyltransferase (CoA-dependent) Activity Negative Regulation Of Stem Cell Population Maintenance Developmental Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II TFIIB-class Transcription Factor Binding Regulation Of Lipid Kinase Activity Rhythmic Process Regulation Of Gene Expression Transcription Coregulator Activity Regulation Of Macromolecule Biosynthetic Process Nucleus Cellular Developmental Process Protein-containing Complex Regulation Of RNA Metabolic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Histone Deacetylase Complex Positive Regulation Of Stem Cell Population Maintenance Transcription Coactivator Binding Chromatin Organization Regulation Of Protein Localization To Nucleus Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Differentiation Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Programmed Cell Death Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II DNA Binding DNA-binding Transcription Factor Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Developmental Process P53 Binding Chromatin Remodeling Negative Regulation Of Biosynthetic Process N-terminal Protein Amino Acid Acetylation Regulation Of Stem Cell Population Maintenance
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