TEDC2 and MIS18A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TEDC2	MIS18A
Description		tubulin epsilon and delta complex 2	MIS18 kinetochore protein A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centriole Cytoskeleton Cilium Cell Projection	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytosol CENP-A Recruiting Complex
	Molecular Function	Protein Binding	Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Smoothened Signaling Pathway	Chromosome Segregation Heterochromatin Formation CENP-A Containing Chromatin Assembly Cell Division Protein Localization To Chromosome, Centromeric Region Pericentric Heterochromatin Organization
Pathways			Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS
Interacting Genes		11 interacting genes: FEZ1 FEZ2 KDM1A KRT27 KRTAP10-3 KRTAP10-7 KRTAP10-9 MDFI MIS18A NOTCH2NLA OGT	30 interacting genes: ABI3 AIMP2 AMOT ATG14 BRD8 C1orf216 CNGA3 DMAP1 FNDC11 GCSH GLYCTK IFT20 MAFIP MBIP MIS18BP1 NDEL1 NTAQ1 NUP58 OIP5 PPP1R13B RTP5 STX11 STX17 TEDC2 THAP1 TSGA10IP TXLNA VMA22 ZNF471 ZNF655
Entrez ID		80178	54069
HPRD ID		07840	10749
Ensembl ID		ENSG00000162062	ENSG00000159055
Uniprot IDs		Q7L2K0	Q9NYP9
PDB IDs			7SFY 7SFZ 8S30
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Negative Regulation Of Autophagosome Assembly Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Macroautophagy Regulation Of Autophagosome Assembly Regulation Of Vacuole Organization Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Negative Regulation Of Cellular Component Organization Cerebral Cortex Development Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Catabolic Process Protein O-acetylglucosaminyltransferase Activity Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Pericentric Heterochromatin Organization CENP-A Recruiting Complex Negative Regulation Of Autophagy	Pericentric Heterochromatin Organization CENP-A Recruiting Complex Autophagosome Membrane Docking Swr1 Complex CENP-A Containing Chromatin Assembly Organelle Localization By Membrane Tethering
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