SLC66A2 and IL10RA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC66A2	IL10RA
Description		solute carrier family 66 member 2	interleukin 10 receptor subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Trans-Golgi Network Cytosol Membrane	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cilium Membrane Apical Plasma Membrane
	Molecular Function	Protein Binding	Interleukin-10 Receptor Activity Protein Binding Interleukin-10 Binding Signaling Receptor Activity
	Biological Process	Retrograde Transport, Endosome To Golgi Phospholipid Translocation	Negative Regulation Of Autophagy Cytokine-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Inflammatory Response Regulation Of Synapse Organization Intestinal Epithelial Structure Maintenance Ubiquitin-dependent Endocytosis Interleukin-10-mediated Signaling Pathway
Pathways			Interleukin-10 signaling Nuclear events stimulated by ALK signaling in cancer
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Interacting Genes		24 interacting genes: ADH5 AQP6 BEST2 CD79A CLCN7 DIABLO FBLN1 FUNDC2 GJA8 GPR152 IL10RA KCNK5 MGLL RHBDD1 SLC10A1 SLC10A6 SLC25A46 SLC35E3 SLC71A2 STX12 TMEM31 TMEM44 TMEM80 ZFYVE27	22 interacting genes: BTRC C1QL4 CDS2 CMTM3 DRD2 HACD1 IL10 IL10RB JAK1 KMT2A MAL NIPAL4 PLPP6 RUSF1 SELENOK SLC38A7 SLC66A2 SLC7A14 SMCO4 TMEM242 TMUB2 YIPF6
Entrez ID		80148	3587
HPRD ID		11454	00911
Ensembl ID		ENSG00000122490	ENSG00000110324
Uniprot IDs		K7ERV4 Q8N2U9	Q13651
PDB IDs			1J7V 1LQS 1Y6K 1Y6M 1Y6N 5IXI 6X93
Enriched GO Terms of Interacting Partners?		Transmembrane Transport Membrane Bile Acid:sodium Symporter Activity Chloride Transmembrane Transport Chloride Transport Bile Acid And Bile Salt Transport Inorganic Anion Transmembrane Transport S-(hydroxymethyl)glutathione Dehydrogenase (NADP+) Activity Formaldehyde Dehydrogenase (NAD+) Activity S-(hydroxymethyl)glutathione Dehydrogenase (NAD+) Activity Nitrate Transmembrane Transporter Activity Monoatomic Anion Transmembrane Transport Inorganic Anion Transport Channel Activity Monoatomic Anion Transport Monoatomic Ion Transport Interleukin-10 Binding Organic Hydroxy Compound Transport Intracellularly Ligand-gated Monoatomic Ion Channel Activity Nucleotide-sugar Transmembrane Transporter Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport	Interleukin-10-mediated Signaling Pathway Membrane Response To Inactivity Type III Interferon-mediated Signaling Pathway
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