ZNF408 and TOP3B

Number of citations of the paper that reports this interaction (PubMedID 15231747)
47

Data Source:
HPRD (two hybrid)

		ZNF408	TOP3B
Description		zinc finger protein 408	DNA topoisomerase III beta
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Condensed Chromosome Nucleus DNA Topoisomerase III-beta-TDRD3 Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	DNA Binding RNA Binding DNA Topoisomerase Activity DNA Topoisomerase Type I (single Strand Cut, ATP-independent) Activity Protein Binding Isomerase Activity RNA Topoisomerase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	DNA Topological Change DNA Repair DNA Recombination Chromosome Segregation
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Femoral neck bone mineral density ( 29499414) Schizophrenia ( 29483656)	Attention function in attention deficit hyperactive disorder ( 26174813) Bipolar disorder ( 31043756) Diastolic blood pressure ( 29208002) Response to selective serotonin reuptake inhibitors in depression ( 27622933)
Interacting Genes		84 interacting genes: AEBP2 AEN APOBEC3C ATRN BAHD1 CALCOCO2 CCDC136 CEP70 CHAF1A CREB3L1 CRELD1 CYSRT1 DDX56 DVL3 EXOSC2 FBLN2 FHL2 FHL5 FSD2 GIPC1 GPATCH2L HNRNPK HOXA5 HOXB9 ID3 KCTD9 KHDRBS3 KRT40 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP12-3 KRTAP4-12 KRTAP5-9 LDOC1 LSM2 LZTS2 MDFI MID2 MIF MRRF MTUS2 NBPF19 NOTCH2NLA PDE4DIP PDLIM4 PICK1 PNMA2 PRAME PRNP PRPF31 PSTPIP1 RALY RALYL RBM10 RBMY1F RBMY1J SAP30BP SPRED1 SSX2IP THAP1 TLE5 TOP3B TRIM23 TRIM41 UBE2I UPF2 USP20 ZBTB26 ZBTB48 ZBTB8A ZBTB9 ZC4H2 ZNF212 ZNF317 ZNF330 ZNF331 ZNF473 ZNF526 ZNF764 ZNF792 ZNF837 ZRANB1	25 interacting genes: ADAMTSL4 AXIN2 C1QBP CENPF CHD8 CHIC2 CIAO1 FASTK FBLN5 GPRASP3 GRN KANK2 KRTAP4-12 MID2 PNMA2 RECQL5 SNRPB SPRED2 SSX2IP TDRD3 TRIM41 UPF2 ZFPM1 ZNF250 ZNF408
Entrez ID		79797	8940
HPRD ID		18338	04662
Ensembl ID		ENSG00000175213	ENSG00000100038
Uniprot IDs		B4DXY4 Q9H9D4	A8K4N2 O95985
PDB IDs			5GVC 5GVE 9C9W 9C9Y 9CA0 9CA1 9CA4 9CAG 9CAH 9CAJ 9CAK 9CAL
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Nucleus Protein Binding Zinc Ion Binding Intermediate Filament Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Keratin Filament Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Spliceosomal Complex MRNA Processing Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of MRNA Processing Regulation Of Primary Metabolic Process RNA Processing Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Muramyl Dipeptide
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?