BBS10 and NR4A1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		BBS10	NR4A1
Description		Bardet-Biedl syndrome 10	nuclear receptor subfamily 4 group A member 1
Image		No pdb structure
GO Annotations	Cellular Component	Cilium Cell Projection	Chromatin Fibrillar Center Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Mitochondrion Cytosol Nuclear Speck Nuclear Membrane
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Lipopolysaccharide Binding DNA Binding Double-stranded DNA Binding DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Nuclear Glucocorticoid Receptor Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Visual Perception Intracellular Protein Localization Response To Light Stimulus Neuronal Action Potential Response To Endoplasmic Reticulum Stress Retinal Cone Cell Differentiation Regulation Of Protein-containing Complex Assembly Negative Regulation Of Neuron Apoptotic Process Photoreceptor Cell Maintenance Photoreceptor Cell Differentiation Chaperone-mediated Protein Complex Assembly Retina Development In Camera-type Eye Retinal Rod Cell Differentiation Cone Retinal Bipolar Cell Differentiation Non-motile Cilium Assembly	Positive Regulation Of Endothelial Cell Proliferation Cell Migration Involved In Sprouting Angiogenesis Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Protein Import Into Nucleus Apoptotic Process Inflammatory Response Signal Transduction Intracellular Receptor Signaling Pathway Detection Of Lipopolysaccharide Endothelial Cell Chemotaxis Skeletal Muscle Cell Differentiation Cellular Response To Vascular Endothelial Growth Factor Stimulus Macrophage Activation Positive Regulation Of Apoptotic Process Cellular Response To Fibroblast Growth Factor Stimulus Fat Cell Differentiation Negative Regulation Of Cell Cycle Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Type B Pancreatic Cell Proliferation Cellular Response To Corticotropin-releasing Hormone Stimulus Non-canonical Inflammasome Complex Assembly
Pathways		BBSome-mediated cargo-targeting to cilium	AKT phosphorylates targets in the nucleus Nuclear Receptor transcription pathway Constitutive Signaling by AKT1 E17K in Cancer
Drugs
Diseases		Bardet-Biedl syndrome (BBS)
GWAS
Interacting Genes		15 interacting genes: CSNK1E FRZB GLIPR1 HDAC6 KRR1 MAP3K7 MAPK6 MAPK8IP2 NR4A1 PTK2 RASA1 RGS2 TM9SF3 TNFSF11 YAE1	87 interacting genes: ABCA5 ABCB11 ABCC13 ABCC6 ABCG8 AKT1 ANKIB1 ARHGEF10L ARHGEF5 ATM ATXN1 BBS10 BCL2 BCL2A1 BCL2L10 CD2AP CDKN2D CHD1L CHD3 CHEK2 CPT1A CUTA DIABLO EP300 ERBB3 FAF1 FXYD3 GADD45GIP1 GK GLOD4 GLUD1 HADHA HES1 HIF1A HNRNPA2B1 HSP90AB1 KAT2B KRTAP10-1 KRTAP10-5 LONRF1 LSS MAP3K1 MAPK1 MAPK8 MED1 MED31 NACAD NCOA1 NCOA2 NCOA3 NCOR2 NDRG1 NFKB1 NR3C1 PGBD1 PML POLA2 PPARG PPBP PPM1A PRDX4 PRDX6 RBL1 ROBO2 RPL7 RPS6KA1 RPS6KA3 RPS6KA5 RPS6KA6 RTN4 RXRA RXRG SERPINA4 SERPING1 SOCS4 STAT3 SUGT1 TCF4 TP53 TRAF2 TRIM28 TUBB4A VASP VHL YWHAZ ZNF331 ZNF579
Entrez ID		79738	3164
HPRD ID		08036	00744
Ensembl ID		ENSG00000179941	ENSG00000123358
Uniprot IDs		Q8TAM1	F5GXF0 P22736 Q6ZMM6
PDB IDs			2QW4 3V3E 3V3Q 4JGV 4KZI 4KZJ 4KZM 4RE8 4REE 4REF 4RZE 4RZF 4RZG 4WHF 4WHG 6KZ5 6LC1 8WUY 8Y7L
Enriched GO Terms of Interacting Partners?		Signal Complex Assembly JNK Cascade MAPK Cascade JUN Kinase Binding Signal Transduction Regulation Of Intracellular Signal Transduction MAP Kinase Activity Positive Regulation Of Signal Transduction Protein Phosphorylation Phosphorylation Positive Regulation Of Cell Communication Cytoplasm Regulation Of Signal Transduction Positive Regulation Of Signaling Negative Regulation Of Cell Growth Response To Amphetamine Regulation Of JNK Cascade Regulation Of Cell Communication Protein Kinase Activity Cell Surface Receptor Signaling Pathway Regulation Of Signaling Non-canonical Wnt Signaling Pathway Negative Regulation Of Hepatocyte Differentiation Regulation Of Apoptotic Process Negative Regulation Of Growth Protein Kinase Binding Positive Regulation Of Epithelial Cell Migration Ephrin Receptor Signaling Pathway Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Beta-tubulin Binding Response To Amine Polyubiquitinated Misfolded Protein Transport Positive Regulation Of Cholangiocyte Proliferation Anatomical Structure Morphogenesis Regulation Of Programmed Cell Death Fc Receptor Signaling Pathway Positive Regulation Of Catabolic Process Regulation Of Cell Morphogenesis Cellular Response To Growth Factor Stimulus Kinase Activity Septin Cytoskeleton Regulation Of Epithelial Cell Migration Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Glycine Import Across Plasma Membrane Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Fever Generation By Positive Regulation Of Prostaglandin Secretion Positive Regulation Of Cellular Response To Oxidative Stress Acetylspermidine Deacetylase Activity Polyamine Deacetylation Spermidine Deacetylation	Intracellular Signal Transduction Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Programmed Cell Death Regulation Of Apoptotic Process TOR Signaling Positive Regulation Of RNA Metabolic Process TORC1 Signaling Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Intracellular Receptor Signaling Pathway Response To Lipid Peroxisome Proliferator Activated Receptor Signaling Pathway Nuclear Receptor-mediated Signaling Pathway Nuclear Receptor Binding Ubiquitin Protein Ligase Binding Programmed Cell Death Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Cell Death Positive Regulation Of Biosynthetic Process Protein-containing Complex Cellular Response To Stress Positive Regulation Of Macromolecule Metabolic Process Regulation Of Small Molecule Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Metabolic Process Apoptotic Process Negative Regulation Of Programmed Cell Death Nucleoplasm Intrinsic Apoptotic Signaling Pathway Response To Nutrient Levels Identical Protein Binding MRNA Transcription Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Biosynthetic Process Negative Regulation Of Apoptotic Process Regulation Of Protein Stability Response To Decreased Oxygen Levels Negative Regulation Of RNA Metabolic Process Response To Hormone Negative Regulation Of Nucleobase-containing Compound Metabolic Process Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Developmental Process Response To Oxygen Levels MRNA Transcription By RNA Polymerase II DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Primary Metabolic Process
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