SUV39H2 and WIZ

Number of citations of the paper that reports this interaction (PubMedID 23455924)
0

Data Source:
BioGRID (two hybrid)

		SUV39H2	WIZ
Description		SUV39H2 histone lysine methyltransferase	WIZ zinc finger
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome	Nucleus Nucleoplasm Midbody Extracellular Exosome
	Molecular Function	Transcription Cis-regulatory Region Binding Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone Methyltransferase Activity Metal Ion Binding Histone H3K9 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone H3K9 Trimethyltransferase Activity S-adenosyl-L-methionine Binding Ubiquitin-like Ligase-substrate Adaptor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Corepressor Binding Protein Binding Zinc Ion Binding Protein-containing Complex Binding Metal Ion Binding Histone Methyltransferase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Circadian Rhythm Cell Differentiation Methylation Epigenetic Programming In The Zygotic Pronuclei Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of DNA-templated Transcription Rhythmic Process Cellular Response To Hypoxia	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nuclear Cell Cycle DNA Replication Protein Stabilization
Pathways		PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	High light scatter reticulocyte percentage of red cells ( 32888494) Monocyte percentage of white cells ( 32888494)
Interacting Genes		43 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD H3C1 ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 VHL WIZ ZNF212 ZNF557 ZNF57	18 interacting genes: C8orf33 CDKN1A CRBN DOK5 EHMT1 EHMT2 OSGEP PIN1 PKNOX1 RCC1 RPP14 RPS10 SLC44A2 SMN1 SUV39H1 SUV39H2 TK1 TSC22D1
Entrez ID		79723	58525
HPRD ID		07580	11686
Ensembl ID		ENSG00000152455	ENSG00000011451
Uniprot IDs		Q9H5I1	A0A2R8YFV2 A0A669KAV7 A0A669KBG4 A0A669KBH9 M0QXA7 O95785
PDB IDs		2R3A 6P0R	8TZX 9DJT 9DJX
Enriched GO Terms of Interacting Partners?		Nucleoplasm Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Histone H3K36me3 Reader Activity Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding	Histone H3K9 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone Methyltransferase Activity Histone H3K9me2 Methyltransferase Activity Histone H3K9 Trimethyltransferase Activity Peptidyl-lysine Dimethylation Histone H3K27 Methyltransferase Activity Negative Regulation Of Gene Expression, Epigenetic Methyltransferase Activity Methylation Nucleus Facultative Heterochromatin Formation Epigenetic Programming In The Zygotic Pronuclei C2H2 Zinc Finger Domain Binding Peptidyl-lysine Methylation Epigenetic Regulation Of Gene Expression Protein-lysine N-methyltransferase Activity Cellular Response To Hypoxia Heterochromatin Formation Cellular Response To Decreased Oxygen Levels Nuclear Body Nucleoplasm Chromosome Cellular Response To Oxygen Levels Epigenetic Programming Of Gene Expression Protein Methylation DNA Methylation-dependent Constitutive Heterochromatin Formation Macromolecule Metabolic Process Cellular Response To Starvation Cis-trans Isomerase Activity Histone H3K56 Methyltransferase Activity Transcription Corepressor Binding Condensed Nuclear Chromosome Response To Starvation Constitutive Heterochromatin Formation PCNA-p21 Complex Negative Regulation Of Cardiac Muscle Tissue Regeneration Thymidine Kinase Activity TRNA N(6)-L-threonylcarbamoyladenine Synthase Activity RNA Metabolic Process Cellular Response To Nutrient Levels Protein Peptidyl-prolyl Isomerization Phosphothreonine Residue Binding Nucleic Acid Metabolic Process ENoSc Complex DNA Synthesis Involved In Mitotic DNA Replication Phenotypic Switching P53 Binding Ethanolamine Transport Ethanolamine Transmembrane Transporter Activity
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