HAUS3 and RCOR3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HAUS3	RCOR3
Description		HAUS augmin like complex subunit 3	REST corepressor 3
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Centrosome Microtubule Organizing Center Spindle Cytosol Cytoskeleton Microtubule Cilium Microtubule Cytoskeleton Ciliary Basal Body Intercellular Bridge HAUS Complex Mitotic Spindle Mitotic Spindle Microtubule	Histone Deacetylase Complex Nucleus Nucleoplasm Transcription Regulator Complex Cytosol
	Molecular Function	Protein Binding	Transcription Corepressor Activity Protein Binding
	Biological Process	Centrosome Cycle Regulation Of Microtubule Nucleation Microtubule Organizing Center Organization Spindle Assembly Cell Division	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS			Plateletcrit ( 32888494)
Interacting Genes		8 interacting genes: ANKRD11 BRME1 CIAO1 GNG13 KDM1A RCOR3 TXLNA TXLNB	75 interacting genes: ABI1 ANKRD11 APP BORCS6 CBY2 CCDC102B CCDC106 CCHCR1 CDR2 CEP55 CEP63 CEP70 EFHC2 FAM81A FSD2 GKAP1 GLRX3 GOLGA2 GPRASP3 GRIPAP1 GSE1 HAUS3 HMBOX1 HOOK2 HSF2BP ICA1L IKZF3 ING5 ISY1-RAB43 KDM1A KRT15 KRT18 KRT19 KRT24 KRT27 KRT31 KRT40 KRT75 LCA5 LHX3 LUZP4 LZTS2 MAGEA6 MARK3 MCC MESD MID2 MIPOL1 MTUS2 NDUFB7 NECAB2 NINL NRDE2 NUTM1 PHF19 PIH1D1 PRDM14 PTPN11 PTTG2 STN1 SUMO2 TFIP11 TRAF1 TRAF2 TRIM27 TRIM42 TRIM54 TSGA10 TULP3 TXLNA USHBP1 VAX1 YWHAQ ZNF383 ZNF688
Entrez ID		79441	55758
HPRD ID		10784	08338
Ensembl ID		ENSG00000214367	ENSG00000117625
Uniprot IDs		Q68CZ6	Q9P2K3
PDB IDs		6PTB 6PTE 7SQK	4CZZ
Enriched GO Terms of Interacting Partners?			Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Cytoskeleton Intermediate Filament Organization Intermediate Filament Structural Molecule Activity Protein Binding Identical Protein Binding Supramolecular Fiber Organization Microtubule TORC1 Complex Assembly Cytoskeleton Organization Epithelial Cell Differentiation Microtubule-based Process Telomeric DNA Binding Centrosome
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