CPLANE2 and TMEM14C

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		CPLANE2	TMEM14C
Description		ciliogenesis and planar polarity effector complex subunit 2	transmembrane protein 14C
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centriole Cytoskeleton Cilium Ciliary Transition Zone Ciliary Basal Body Cell Projection Ciliary Base	Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding	Protein Binding Transmembrane Transporter Activity
	Biological Process	Endocardial Cushion Fusion Exocytosis Smoothened Signaling Pathway Intracellular Protein Localization Regulation Of Smoothened Signaling Pathway Protein Transport Protein Processing Regulation Of Exocytosis Cell Projection Organization Regulation Of Vesicle Fusion Axoneme Assembly Limb Development Cilium Assembly Cranial Skeletal System Development	Heme Biosynthetic Process Mitochondrial Transport Erythrocyte Differentiation Transmembrane Transport Regulation Of Heme Biosynthetic Process
Pathways
Drugs
Diseases
GWAS			Itch intensity from mosquito bite adjusted by bite size ( 28199695) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		8 interacting genes: CROCCP2 CROCCP3 FUZ IFFO2 IMPDH2 MSLN RND3 TMEM14C	51 interacting genes: AQP6 ARL13B BCL2L13 BIK CLDN5 COMT COQ9 CPLANE2 CREB3 CREB3L1 CYB5R3 EBP ELOVL7 FAM209A GJB1 GORAB GPR152 GPX8 HSD17B13 KASH5 LMNA LNX1 MARCHF8 MFF MMGT1 MTERF3 MUC1 NCAPH2 NCR3LG1 PDZK1IP1 PLIN3 RCHY1 SAR1A SDC3 SHANK3 SLC10A6 SLC18A1 SLC35H1 SSMEM1 STX1A SYT1 TMEM14B TMEM31 TMEM35A TMEM52B TMEM79 TMEM86B TMX2 VSIR ZDHHC15 ZFYVE27
Entrez ID		79363	51522
HPRD ID		14399	15524
Ensembl ID		ENSG00000132881	ENSG00000111843
Uniprot IDs		Q9BU20	Q9P0S9
PDB IDs			2LOS
Enriched GO Terms of Interacting Partners?		IMP Dehydrogenase Activity Regulation Of Heme Biosynthetic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Negative Regulation Of Neural Crest Formation	Membrane Endoplasmic Reticulum Membrane Identical Protein Binding Protein Binding Mitochondrial Membrane Endoplasmic Reticulum Clathrin-sculpted Monoamine Transport Vesicle Membrane Organelle Organization Norepinephrine Transport
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