TRAPPC6A and TRAPPC3L

Number of citations of the paper that reports this interaction (PubMedID 21525244)
43

Data Source:
BioGRID (two hybrid, two hybrid)

		TRAPPC6A	TRAPPC3L
Description		trafficking protein particle complex subunit 6A	trafficking protein particle complex subunit 3L
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex TRAPPIII Protein Complex	Endoplasmic Reticulum Golgi Apparatus Cytosol TRAPP Complex Cis-Golgi Network Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle-mediated Transport Golgi Vesicle Transport COPII Vesicle Coating Vesicle Tethering	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Golgi Vesicle Transport
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs		S-palmitoyl-L-cysteine
Diseases
GWAS		Alanine aminotransferase levels ( 33339817) Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Aspartate aminotransferase levels ( 33339817) Cerebrospinal fluid AB1-42 levels ( 28247064)	Refractive error ( 32231278) Ulcerative colitis ( 28067908)
Interacting Genes		47 interacting genes: BAG4 CAVIN2 CD2BP2 CRYAB CTDSP1 EFS EYA2 FOXN1 GGA3 GINS3 GOLGA6A GORASP2 HOXA1 HSPB8 IKZF3 INCA1 KANK4 KRTAP13-2 LHX4 MYOZ3 PAX6 PFDN5 PRR22 RAB3IP RAD54B REL RUSC1 SCOC SERTAD3 SF3B5 SMUG1 TAX1BP1 TEPSIN TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B TRIM35 TTC23 UBAP2 YPEL3 ZFP90 ZMIZ2 ZNRD2	12 interacting genes: TRAPPC1 TRAPPC10 TRAPPC11 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC8 TRAPPC9
Entrez ID		79090	100128327
HPRD ID		14503	19437
Ensembl ID		ENSG00000007255	ENSG00000173626
Uniprot IDs		B7TZ90 O75865	Q5T215
PDB IDs		2C0J 2J3T
Enriched GO Terms of Interacting Partners?		TRAPP Complex TRAPPII Protein Complex Vesicle Tethering Vesicle Coating TRAPPIII Protein Complex Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Vesicle Transport COPII Vesicle Coating Intra-Golgi Vesicle-mediated Transport Golgi Apparatus Vesicle Organization Cis-Golgi Network Nucleus Cis-Golgi Network Membrane Negative Regulation Of Amyloid Fibril Formation	TRAPP Complex Vesicle Tethering Vesicle Coating TRAPPIII Protein Complex Endoplasmic Reticulum To Golgi Vesicle-mediated Transport COPII Vesicle Coating TRAPPII Protein Complex Golgi Vesicle Transport Vesicle Organization Vesicle-mediated Transport Intracellular Transport Cellular Localization Establishment Of Localization In Cell Golgi Apparatus Organelle Organization Protein-containing Complex Assembly Protein-containing Complex Organization Cytosol Endoplasmic Reticulum Cellular Component Assembly Cytoplasm Golgi Organization Trans-Golgi Network Cis-Golgi Network TRAPPI Protein Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Positive Regulation Of Protein Localization To Kinetochore Regulation Of Kinetochore Assembly Regulation Of Centromere Complex Assembly Constitutive Secretory Pathway Collagen Biosynthetic Process Perinuclear Region Of Cytoplasm Regulation Of Protein Complex Stability Early Endosome To Golgi Transport
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