NOC4L and DUSP29

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NOC4L	DUSP29
Description		nucleolar complex associated 4 homolog	dual specificity phosphatase 29
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Membrane Noc4p-Nop14p Complex Nuclear Membrane Small-subunit Processome	Nucleus Cytoplasm Protein-containing Complex
	Molecular Function	RNA Binding Protein Binding	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Hydrolase Activity Phosphatase Activity MAP Kinase Phosphatase Activity Protein Homodimerization Activity
	Biological Process	RRNA Processing Ribosome Biogenesis	Protein Dephosphorylation Glucose Homeostasis Muscle Cell Differentiation Negative Regulation Of MAPK Cascade Negative Regulation Of ERK1 And ERK2 Cascade
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Body mass index ( 26426971) Hirschsprung disease ( 26887379) Response to antidepressants (symptom improvement) ( 29160301) Response to SSRI (symptom remission) ( 29160301)
Interacting Genes		24 interacting genes: BHLHE40 CEBPA DAZAP2 DNAJA3 DUSP29 EPM2AIP1 IKZF1 KRT15 KRTAP19-6 LINC00839 LNPK NECAB2 NT5C2 OGT OXER1 PICK1 PLSCR1 PRSS23 TSC22D4 UBQLN2 USHBP1 VIM ZBTB42 ZNRD2	25 interacting genes: AATK ARPC3 ASPA C17orf75 CNTROB DDIT4L EPHA2 ERBB3 GOLGA6A IGF1R LMTK2 LNX1 NIF3L1 NOC4L PICK1 POLR2G PSMB5 PTK7 RNF40 ROR1 ROR2 SRSF11 STX11 TCF4 TEPSIN
Entrez ID		79050	338599
HPRD ID		14543	16846
Ensembl ID		ENSG00000184967	ENSG00000188716
Uniprot IDs		Q9BVI4	Q68J44
PDB IDs			2Y96
Enriched GO Terms of Interacting Partners?		Negative Regulation Of G Protein-coupled Receptor Internalization Protein Domain Specific Binding Identical Protein Binding Carbohydrate Homeostasis Glucose Homeostasis Negative Regulation Of Endocytosis Regulation Of Receptor Internalization Negative Regulation Of Receptor Internalization Negative Regulation Of Cellular Component Organization	Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Kinase Activity Protein Tyrosine Kinase Activity Receptor Complex Kinase Activity Glial Cell Development Dendritic Spine Maintenance Coreceptor Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Transferase Activity ATP Binding
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