RNF113A and PPP4R3A

Number of citations of the paper that reports this interaction (PubMedID 35819319)
55

Data Source:
BioGRID (affinity chromatography technology, pull down, affinity chromatography technology)

		RNF113A	PPP4R3A
Description		ring finger protein 113A	protein phosphatase 4 regulatory subunit 3A
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex Nuclear Speck U2-type Precatalytic Spliceosome	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cytoskeleton Nuclear Speck Protein Phosphatase 4 Complex
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Phosphatase Regulator Activity Protein Phosphatase Activator Activity
	Biological Process	MRNA Splicing, Via Spliceosome DNA Repair MRNA Processing DNA Damage Response RNA Splicing Protein Ubiquitination SnoRNA Splicing Negative Regulation Of Chemokine-mediated Signaling Pathway	Gluconeogenesis DNA Damage Response Positive Regulation Of Gluconeogenesis Regulation Of Double-strand Break Repair
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Decline in glucose metabolism in posterior cingulate cortex ( 29130521)
Interacting Genes		10 interacting genes: CCAR1 CXCR4 PPP4R3A RBM39 SMYD3 SNRNP200 TERF2 TRIM8 UBE2D3 UBE2U	6 interacting genes: CASK CDK1 CEBPA MAPK14 PEA15 RNF113A
Entrez ID		7737	55671
HPRD ID		06760	11176
Ensembl ID		ENSG00000125352	ENSG00000100796
Uniprot IDs		O15541	Q6IN85 Q8N6W1
PDB IDs		5Z56 5Z58 6FF4 6FF7 7DVQ 7QTT 8CH6 8I0R 8I0S 8I0T 8I0U	6R8I
Enriched GO Terms of Interacting Partners?		Telomere Cap Complex Negative Regulation Of Telomere Maintenance Via Recombination DNA Damage Response Axonal Transport Of Messenger Ribonucleoprotein Complex Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of Telomere Single Strand Break Repair Telomeric Loop Formation Negative Regulation Of DNA Recombination At Telomere Post-translational Protein Modification Protein Polyubiquitination Ubiquitin Protein Ligase Activity Protein Modification By Small Protein Conjugation Protein Ubiquitination Ubiquitin Conjugating Enzyme Activity C-X-C Motif Chemokine 12 Receptor Activity Positive Regulation Of Macrophage Migration Inhibitory Factor Signaling Pathway Spliceosome Conformational Change To Release U4 (or U4atac) And U1 (or U11) Cis Assembly Of Pre-catalytic Spliceosome Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of T-circle Formation Regulation Of Macrophage Migration Inhibitory Factor Signaling Pathway Nucleoplasm Negative Regulation Of Mitotic Recombination Histone H3K36 Dimethyltransferase Activity Telomerase Activity Protection From Non-homologous End Joining At Telomere Response To Stress Regulation Of Mitotic Recombination Shelterin Complex Nucleic Acid Metabolic Process Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process CXCL12-activated CXCR4 Signaling Pathway Myosin Light Chain Binding C-X-C Chemokine Receptor CXCR4 Signaling Pathway RS Domain Binding U1 SnRNP Binding Protein Phosphatase 4 Complex Histone H4 Methyltransferase Activity HULC Complex Negative Regulation Of Telomere Capping Regulation Of Metabolic Process Chemokine (C-X-C Motif) Ligand 12 Signaling Pathway C-X-C Chemokine Receptor Activity RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding Nuclear Telomere Cap Complex Telomeric D-loop Disassembly Double-stranded Telomeric DNA Binding Histone H3K4 Trimethyltransferase Activity	Positive Regulation Of Heart Growth Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Intracellular Signaling Cassette MAPK Cascade Positive Regulation Of Protein Import Into Nucleus Protein Serine Kinase Activity Negative Regulation Of Cell Cycle Positive Regulation Of Organ Growth Regulation Of Protein Import Into Nucleus Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Heart Growth Protein Serine/threonine Kinase Activity Positive Regulation Of Fat Cell Differentiation Energy Homeostasis Regulation Of D-glucose Import Regulation Of D-glucose Transmembrane Transport Pronuclear Fusion RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Nucleobase-containing Compound Metabolic Process Positive Regulation Of Intracellular Protein Transport Regulation Of Organ Growth Protein Kinase Activity Positive Regulation Of Protein Localization To Nucleus DNA Damage Checkpoint Signaling Cellular Response To Tumor Necrosis Factor Mitotic DNA-templated DNA Replication Cyclin B1-CDK1 Complex Regulation Of Nucleocytoplasmic Transport Small Molecule Metabolic Process Cyclin A1-CDK1 Complex Cyclin A2-CDK1 Complex Response To Tumor Necrosis Factor Response To Vitamin B2 C/EBP Complex SnoRNA Splicing Cellular Response To Stress Positive Regulation Of Intracellular Transport Mitotic DNA Replication DNA Synthesis Involved In Mitotic DNA Replication Regulation Of Intracellular Protein Transport Regulation Of Transport Kinase Activity Cyclin-dependent Protein Kinase Activity Regulation Of Fat Cell Differentiation CHOP-C/EBP Complex Nuclear Matrix Myeloid Leukocyte Differentiation Regulation Of Synaptic Membrane Adhesion Regulation Of Cell Population Proliferation
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