XK and CLGN

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		XK	CLGN
Description		X-linked Kx blood group antigen, Kell and VPS13A binding protein	calmegin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity	Calcium Ion Binding Protein Folding Chaperone Unfolded Protein Binding
	Biological Process	Amino Acid Transport Intracellular Calcium Ion Homeostasis Regulation Of Cell Size Intracellular Magnesium Ion Homeostasis Regulation Of Axon Diameter Myelination Skeletal Muscle Fiber Development	Protein Folding Single Fertilization Binding Of Sperm To Zona Pellucida ERAD Pathway Protein-containing Complex Assembly
Pathways		Peptide ligand-binding receptors
Drugs
Diseases		Core neuroacanthocytosis syndromes, including: Chorea-acanthocytosis (ChAc); McLeod syndrome (MLS); Huntington's disease-like 2 (HDL2); Pantothenate kinase associated neurodegeneration (PKAN) McLeod syndrome
GWAS			Diastolic blood pressure x sodium interaction (2df test) ( 27271309) Malaria ( 31844061) Mean arterial pressure x sodium interaction (2df test) ( 27271309) Select biomarker traits ( 17903293) Systolic blood pressure x sodium interaction (2df test) ( 27271309) Triglyceride levels in HIV infection ( 33109212)
Interacting Genes		4 interacting genes: CLGN CSNK2A1 KEL PRKCA	4 interacting genes: ADAM2 GDE1 LINC00839 XK
Entrez ID		7504	1047
HPRD ID		02444	03513
Ensembl ID		ENSG00000047597	ENSG00000153132
Uniprot IDs		P51811	A0A140VKG2 O14967
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Folding Macromolecule Catabolic Process Protein Catabolic Process Protein Metabolic Process Negative Regulation Of Translation Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Angiotensin-activated Signaling Pathway Histone H3T6 Kinase Activity Alphav-beta3 Integrin-PKCalpha Complex Protein Kinase C Signaling Positive Regulation Of Aggrephagy Regulation Of Axon Diameter Regulation Of Angiotensin-activated Signaling Pathway Proteolysis Intracellular Magnesium Ion Homeostasis Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Desmosome Assembly Aggrephagy Double-strand Break Repair Via Classical Nonhomologous End Joining Protein Serine Kinase Activity Protein Targeting To Vacuole Involved In Autophagy Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Protein Serine/threonine Kinase Activity Regulation Of Translation Magnesium Ion Homeostasis Regulation Of Cell Projection Size Mitotic Nuclear Membrane Disassembly Diacylglycerol Binding Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Desmosome Organization Positive Regulation Of Bone Resorption Positive Regulation Of Macrophage Differentiation Membrane Disassembly Nuclear Membrane Disassembly Response To Phorbol 13-acetate 12-myristate Negative Regulation Of Glial Cell Apoptotic Process Response To Corticosterone MRNA Methylguanosine-cap Decapping Diacylglycerol-dependent Serine/threonine Kinase Activity	Ethanolamine Metabolic Process Glycerophosphoinositol Glycerophosphodiesterase Activity Intracellular Magnesium Ion Homeostasis Regulation Of Axon Diameter N-acylethanolamine Metabolic Process Glycerophosphodiester Phosphodiesterase Activity Regulation Of Cell Projection Size Magnesium Ion Homeostasis
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