VTN and SNTG1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VTN	SNTG1
Description		vitronectin	syntrophin gamma 1
Image
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Extracellular Space Endoplasmic Reticulum Golgi Lumen Symbiont-containing Vacuole Extracellular Matrix Rough Endoplasmic Reticulum Lumen Extracellular Exosome Alphav-beta3 Integrin-vitronectin Complex Blood Microparticle Protein Complex Involved In Cell-matrix Adhesion Peptidase Inhibitor Complex	Nucleus Cytoplasm Cytoskeleton Dystrophin-associated Glycoprotein Complex Syntrophin Complex Ruffle Membrane
	Molecular Function	Scavenger Receptor Activity Integrin Binding Extracellular Matrix Structural Constituent Protein Binding Collagen Binding Heparin Binding Polysaccharide Binding Identical Protein Binding Extracellular Matrix Binding	Actin Binding Structural Molecule Activity Protein Binding
	Biological Process	Immune Response Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Smooth Muscle Cell Migration Vesicle-mediated Transport Cell Migration Cell Differentiation Regulation Of Cell Adhesion Negative Regulation Of Blood Coagulation Extracellular Matrix Organization Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Adhesion Mediated By Integrin Endodermal Cell Differentiation Negative Regulation Of Proteolysis Positive Regulation Of Receptor-mediated Endocytosis Oligodendrocyte Differentiation Protein Polymerization Negative Regulation Of Fibrinolysis Smooth Muscle Cell-matrix Adhesion Positive Regulation Of Wound Healing Liver Regeneration Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Integrin-mediated Signaling Pathway	Cell Communication
Pathways		Molecules associated with elastic fibres Integrin cell surface interactions Syndecan interactions ECM proteoglycans ECM proteoglycans Regulation of Complement cascade Developmental Lineage of Pancreatic Ductal Cells
Drugs		Abciximab Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Heel bone mineral density ( 30598549) LDL cholesterol ( 30275531) Low density lipoprotein cholesterol levels ( 32154731 33339817) Osteoprotegerin levels ( 25080503)	Abstraction and mental flexibility ( 31596458) Age at first sexual intercourse ( 34211149) Diastolic blood pressure ( 27841878) General risk tolerance (MTAG) ( 30643258) Interleukin-6 levels ( 22205395) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681) Pulmonary function ( 17903307) Pulse pressure ( 27841878) Remission after SSRI treatment in MDD or openness ( 29559929) Response to SSRI in MDD or openness ( 29559929) Superior frontal gyrus grey matter volume ( 25335168) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		50 interacting genes: ADH5 ADTRP AMPH APP CBX1 CD247 CKS2 COPS5 CRADD CSNK2A1 DLG2 DLG3 EGF ETV7 FGF2 FGG GEM GLUD1 GOPC HGF IGF2 IGFBP5 ITGA2B ITGA5 ITGA8 ITGAV ITGB3 ITGB6 ITGB8 KNG1 LACRT LNX2 PLAUR POMC PRDX4 PRKACA PRKCA PRKCB PRKCG PVR RHOXF1 RPL13A SERPINE1 SIX1 SNTG1 TGFB1 TGFB2 TNFRSF11B UBQLN2 VEGFA	16 interacting genes: ADRA1D DGKZ DMD DTNA DTNB FGF2 KCNA4 PLEKHA1 PLEKHA2 SNAP23 STXBP3 TGFBR1 UBC VANGL2 VPS45 VTN
Entrez ID		7448	54212
HPRD ID		01902	16373
Ensembl ID		ENSG00000109072	ENSG00000147481
Uniprot IDs		D9ZGG2 P04004	A0A2R8Y5T2 A0A2R8Y631 B2RA84 Q9NSN8
PDB IDs		1OC0 1S4G 1SSU 2JQ8 3BT1 3BT2 4K24 6O5E 7RJ9	7PC7 7PC8 7QQN
Enriched GO Terms of Interacting Partners?		Platelet Alpha Granule Lumen Integrin Complex Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Signal Transduction Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cell Surface Receptor Signaling Pathway Regulation Of Programmed Cell Death Integrin Binding Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Cell-matrix Adhesion Regulation Of Apoptotic Process Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Locomotion Cell-cell Adhesion Positive Regulation Of Vasculature Development Cell Surface Regulation Of Vesicle-mediated Transport Regulation Of Cell Communication Regulation Of Signaling Signal Transduction Regulation Of Signal Transduction Positive Regulation Of Epithelial Tube Formation Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Apoptotic Process Signaling Receptor Binding Negative Regulation Of Multicellular Organismal Process Cell Adhesion Growth Factor Activity Angiogenesis Cell-substrate Adhesion Integrin-mediated Signaling Pathway Cell Adhesion Mediated By Integrin Regulation Of Endocytosis Regulation Of Protein Metabolic Process Regulation Of Multicellular Organismal Process Negative Regulation Of Programmed Cell Death Alphav-beta3 Integrin-PKCalpha Complex Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Regulation Of Protein Localization Regulation Of Vasculature Development Regulation Of Transport Positive Regulation Of Angiogenesis Positive Regulation Of Protein Localization Regulation Of Morphogenesis Of An Epithelium Anatomical Structure Formation Involved In Morphogenesis Positive Regulation Of MAPK Cascade Regulation Of Cell Migration Positive Regulation Of Morphogenesis Of An Epithelium	Angiogenesis Involved In Coronary Vascular Morphogenesis Plasma Membrane PDZ Domain Binding Wound Healing Specific Granule Membrane Cell-cell Signaling Signaling Cell Communication Phosphatidylinositol-3,4-bisphosphate Binding Alpha1-adrenergic Receptor Activity Striated Muscle Contraction Lateral Plasma Membrane Animal Organ Development Growth Factor Dependent Regulation Of Skeletal Muscle Satellite Cell Proliferation Regulation Of Cardiac Muscle Cell Proliferation Endothelial Cell Proliferation Regulation Of Animal Organ Morphogenesis Response To Wortmannin Positive Regulation Of Inner Ear Receptor Cell Differentiation Negative Regulation Of Wound Healing Positive Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Tube Morphogenesis Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Retinal Cell Programmed Cell Death Cell Migration Animal Organ Morphogenesis Response To Wounding Lymphatic Endothelial Cell Migration Regulation Of Heart Growth Positive Regulation Of Cell Fate Specification Positive Regulation Of Lens Fiber Cell Differentiation Regulation Of Stem Cell Proliferation Endothelial Cell Migration Positive Regulation Of Inner Ear Auditory Receptor Cell Differentiation Cell Motility Positive Regulation Of Stem Cell Proliferation Corticotropin Hormone Secreting Cell Differentiation Syntaxin Binding Tertiary Granule Muscle Tissue Morphogenesis Post-embryonic Development Roof Of Mouth Development Proepicardium Development Vascular Endothelial Cell Proliferation Epicardium Morphogenesis Transforming Growth Factor Beta Ligand-receptor Complex Symbiont-containing Vacuole Smooth Muscle Cell-matrix Adhesion Rough Endoplasmic Reticulum Lumen
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