TPD52L1 and GPR135

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TPD52L1	GPR135
Description		TPD52 like 1	G protein-coupled receptor 135
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Perinuclear Region Of Cytoplasm	Endosome Plasma Membrane Endosome Membrane Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity	G Protein-coupled Receptor Activity Protein Binding Arrestin Family Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of MAP Kinase Activity Positive Regulation Of JNK Cascade Positive Regulation Of Apoptotic Signaling Pathway	Signal Transduction G Protein-coupled Receptor Signaling Pathway
Pathways		Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS		Heel bone mineral density x serum urate levels interaction ( 34046847) Night sleep phenotypes ( 27126917)	Brain morphology (MOSTest) ( 32665545) Obsessive-compulsive disorder ( 30456828)
Interacting Genes		15 interacting genes: ABL2 DAPK1 EIF3J GPR135 HDAC1 MAL2 MAP3K5 PAK6 PBX3 TPD52 TPD52L2 TPD52L3 YAE1 YWHAB YWHAZ	3 interacting genes: MAGED1 TPD52L1 ZDHHC17
Entrez ID		7164	64582
HPRD ID		07236	16263
Ensembl ID		ENSG00000111907	ENSG00000181619
Uniprot IDs		E9PPQ1 J3KNE7 Q16890	Q8IZ08
PDB IDs
Enriched GO Terms of Interacting Partners?		Phosphoserine Residue Binding Cytoplasm Protein Kinase Activity Cellular Response To Oxidative Stress DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Protein Domain Specific Binding Cellular Response To Starvation Response To Starvation Posterior Compartment Specification Anterior Compartment Pattern Formation Negative Regulation Of Protein Localization To Nucleus Protein Sequestering Activity	Positive Regulation Of Apoptotic Signaling Pathway Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Positive Regulation Of Cell Communication Regulation Of Programmed Cell Death Identical Protein Binding Positive Regulation Of Signaling Positive Regulation Of Signal Transduction Protein-cysteine S-myristoyltransferase Activity Protein-cysteine S-stearoyltransferase Activity Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Lipoprotein Transport Regulation Of Neurotrophin TRK Receptor Signaling Pathway Protein Palmitoylation Palmitoyltransferase Activity Regulation Of Modification Of Synaptic Structure Golgi-associated Vesicle Membrane Protein-cysteine S-palmitoyltransferase Activity Regulation Of Branching Involved In Ureteric Bud Morphogenesis Regulation Of MAPK Cascade Protein Lipidation Regulation Of Signal Transduction Positive Regulation Of MAP Kinase Activity Positive Regulation Of Morphogenesis Of An Epithelium Regulation Of Kidney Development Regulation Of Cell Communication Regulation Of Signaling Negative Regulation Of Protein Localization To Nucleus G2/M Transition Of Mitotic Cell Cycle Cell Cycle G2/M Phase Transition Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Morphogenesis Of A Branching Structure
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