SLC19A1 and KRT26

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC19A1	KRT26
Description		solute carrier family 19 member 1	keratin 26
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Brush Border Membrane	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding Folic Acid Binding Organic Anion Transmembrane Transporter Activity Folic Acid Transmembrane Transporter Activity Folate:monoatomic Anion Antiporter Activity Antiporter Activity Methotrexate Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity 2',3'-cyclic GMP-AMP Binding Vitamin Transmembrane Transporter Activity Cyclic-GMP-AMP Transmembrane Transporter Activity	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Xenobiotic Transmembrane Transport Female Pregnancy Response To Xenobiotic Stimulus Response To Toxic Substance Organic Anion Transport Folic Acid Transport Folic Acid Metabolic Process Vitamin Transport Methotrexate Transport Monoatomic Anion Transmembrane Transport Folate Transmembrane Transport Cyclic-GMP-AMP Transmembrane Import Across Plasma Membrane Positive Regulation Of CGAS/STING Signaling Pathway Transport Across Blood-brain Barrier Folate Import Across Plasma Membrane	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization
Pathways		Metabolism of folate and pterines	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Ankle injury ( 28957384)	Asthma ( 31959851) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		3 interacting genes: KRT26 SH3BGR TRAPPC10	30 interacting genes: BLOC1S2 CCDC146 FAM86C1P HGS KIFC3 KRT1 KRT3 KRT4 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT81 KRT85 MCCD1 SLC19A1 SNAPIN SUOX TRIB3 TXLNB UCHL5 USHBP1 WASHC1
Entrez ID		6573	353288
HPRD ID		02691	17243
Ensembl ID		ENSG00000173638	ENSG00000186393
Uniprot IDs		P41440	Q7Z3Y9
PDB IDs		7TX6 7TX7 7XPZ 7XQ0 7XQ1 7XQ2 7XTK 8DEP 8GOE 8GOF 8HII 8HIJ 8HIK 9JOZ 9JRI 9JRK 9JRL 9JRM 9JRN
Enriched GO Terms of Interacting Partners?		TRAPPII Protein Complex TRAPP Complex Early Endosome To Golgi Transport	Structural Constituent Of Skin Epidermis Keratin Filament Keratinization Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Extracellular Exosome Cytosol Regulation Of Lysosome Size BORC Complex Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane BLOC-1 Complex Anterograde Synaptic Vesicle Transport Regulation Of Vesicle Size Protein Binding Methotrexate Transport Methotrexate Transmembrane Transporter Activity Folate:monoatomic Anion Antiporter Activity Sulfite Oxidase Activity Positive Regulation Of Late Endosome To Lysosome Transport Gamma-tubulin Binding Synaptic Vesicle Transport Epidermis Development Melanosome Organization Pigment Granule Organization
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