SEC62 and ZNF24

Number of citations of the paper that reports this interaction (PubMedID 20195357)
57

Data Source:
BioGRID (pull down)

		SEC62	ZNF24
Description		SEC62 preprotein translocation factor	zinc finger protein 24
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Membrane	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Signaling Receptor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Cotranslational Protein Targeting To Membrane Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Protein Transport Post-translational Protein Targeting To Membrane, Translocation	Regulation Of Transcription By RNA Polymerase II Myelination Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Cadmium levels ( 26025379)
Interacting Genes		8 interacting genes: CIC CTNNB1 GABARAP GABARAPL1 MAP1LC3A OGT SEC63 ZNF24	47 interacting genes: APLP1 CEP126 COPS6 CRMP1 DDX6 DZIP3 EEF1A1 EEF1G ERG28 FAM161A FANCA HAP1 HMGB1 KAT5 LMO1 LMO2 LRIF1 MAP1LC3C MID2 NEK6 PPP1CC PRPF31 RBM48 SCAND1 SEC62 SETDB1 TCAF1 TP53 TRIM25 TRIM41 UBE2I UNC119 UTP14A YJU2B ZBTB16 ZGPAT ZKSCAN8 ZNF165 ZNF174 ZNF410 ZNF446 ZNF620 ZNHIT3 ZSCAN12 ZSCAN16 ZSCAN22 ZSCAN32
Entrez ID		7095	7572
HPRD ID		03706	01921
Ensembl ID		ENSG00000008952	ENSG00000172466
Uniprot IDs		Q99442	P17028
PDB IDs		7BRT	1X6E 3LHR
Enriched GO Terms of Interacting Partners?		Mitophagy Cellular Response To Nitrogen Starvation Autophagy Of Mitochondrion Phosphatidylethanolamine Binding Macroautophagy Autophagosome Maturation Autophagosome Membrane Cellular Response To Nutrient Levels Ubiquitin Protein Ligase Binding Autophagy Autophagosome Autophagosome Assembly Autophagosome Organization Phospholipid Binding GABA Receptor Binding Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Protein-containing Complex Disassembly Response To Nutrient Levels Vacuole Organization Regulation Of Protein Localization To Synapse Cellular Response To Starvation Regulation Of Protein Ubiquitination Regulation Of Receptor Localization To Synapse Regulation Of Rac Protein Signal Transduction Response To Starvation Regulation Of Post-translational Protein Modification Beta-tubulin Binding Organelle Assembly Glial Cell Fate Determination Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Sec62/Sec63 Complex Microtubule Mesenchymal Stem Cell Differentiation Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic Beta-catenin-ICAT Complex Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Renal Inner Medulla Development Scrib-APC-beta-catenin Complex Renal Outer Medulla Development Renal Vesicle Formation Positive Regulation Of Branching Involved In Lung Morphogenesis Neural Plate Development Negative Regulation Of Post-translational Protein Modification Catabolic Process Oviduct Development Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Fungiform Papilla Formation	Zinc Ion Binding Nucleus Regulation Of Macromolecule Metabolic Process Metal Ion Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Gene Expression Protein Binding Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Transcription Coactivator Activity DNA-binding Transcription Factor Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding
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