TEAD4 and CCDC172

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		TEAD4	CCDC172
Description		TEA domain transcription factor 4	coiled-coil domain containing 172
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Protein-DNA Complex	Cytoplasm Cilium Cell Projection Sperm Midpiece
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding	Protein Binding
	Biological Process	Skeletal System Development In Utero Embryonic Development Cell Fate Specification Blastocyst Formation Trophectodermal Cell Fate Commitment DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Muscle Organ Development Embryo Implantation Hippo Signaling Cell Fate Commitment Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Positive Regulation Of Stem Cell Population Maintenance
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription Formation of axial mesoderm Zygotic genome activation (ZGA) Regulation of PD-L1(CD274) transcription
Drugs
Diseases
GWAS		Narcolepsy with cataplexy ( 23496005)	Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383) Malaria ( 31844061) Severe autoimmune type 2 diabetes ( 34737425)
Interacting Genes		50 interacting genes: CCDC125 CCDC172 CCDC85B CCNDBP1 CDR2 CEP55 CEP70 CRYAA CTBP1 DYDC1 EXOC3-AS1 FBXO7 GOLGA2 GOLGA6L9 HAUS1 HOMEZ INCA1 KIAA0753 KRT27 KRT31 KRT40 KRTAP10-3 LDOC1 LZTS2 MDFI MTUS2 MYH7 NUTM1 PDE4DIP PFKM PNMA1 PRDM14 PRKAR1B RABGEF1 RASSF10 RUNDC3A RUNX1 SAT1 SESTD1 SORBS3 SSX2IP TLE5 TRAF1 TRIM54 VGLL1 VGLL3 VPS52 VTA1 WWTR1 YAP1	20 interacting genes: CATSPERT DCTN2 FAM13C FAM161B HDDC3 ISCU KDM1A MRPL11 MSGN1 NEFL PCDHB12 PLEKHF2 PRKAA2 PSTPIP1 SH2D4A SMARCE1 TCHP TEAD4 TXNDC9 VPS9D1
Entrez ID		7004	374355
HPRD ID		03421	18604
Ensembl ID		ENSG00000197905	ENSG00000182645
Uniprot IDs		Q15561	P0C7W6
PDB IDs		5GZB 5NO6 5OAQ 6GE3 6GE4 6GE5 6GE6 6GEC 6GEE 6GEG 6GEI 6GEK 6HIK 6Q2X 6Q36 6SEN 6SEO 8A8R 8C17 8CAA
Enriched GO Terms of Interacting Partners?		Cytoskeleton Microtubule Organizing Center Organization Centrosome Cycle Centrosome Cytoplasm Cardiac Muscle Tissue Regeneration Protein Binding Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Keratin Filament
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