TRB and CD1D

Number of citations of the paper that reports this interaction (PubMedID 12133957)
0

Data Source:
HPRD (in vivo)

		TRB	CD1D
Description		T cell receptor beta locus	CD1d molecule
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane T Cell Receptor Complex Alpha-beta T Cell Receptor Complex	Extracellular Space Cytoplasm Lysosome Lysosomal Membrane Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane External Side Of Plasma Membrane Cell Surface Endosome Membrane Membrane Basolateral Plasma Membrane
	Molecular Function	Signaling Receptor Activity	Protein Binding Beta-2-microglobulin Binding Lipid Antigen Binding Endogenous Lipid Antigen Binding Exogenous Lipid Antigen Binding Cell Adhesion Molecule Binding Lipopeptide Binding
	Biological Process	Detection Of Tumor Cell Immune System Process T Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Cell Surface Receptor Signaling Pathway	Positive Regulation Of T Cell Mediated Cytotoxicity Immune System Process Immune Response Detection Of Bacterium Heterotypic Cell-cell Adhesion Positive Regulation Of T Cell Proliferation T Cell Selection Innate Immune Response Positive Regulation Of Innate Immune Response Antigen Processing And Presentation, Endogenous Lipid Antigen Via MHC Class Ib Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs			cis-tetracosenoyl sulfatide
Diseases
GWAS		Narcolepsy ( 24204295)	Dental caries (decayed and filled deciduous teeth) ( 31533690)
Interacting Genes		14 interacting genes: CD1D CD247 CD3D CD3E CD3G CTCF HLA-A HLA-B HLA-DRB1 NCOA6 TAF1B TRA TRAT1 TRD	8 interacting genes: APOE B2M CALR CANX CD74 P4HB PTPRC TRB
Entrez ID		6957	912
HPRD ID		01739	01780
Ensembl ID			ENSG00000158473
Uniprot IDs			A0A669KAZ2 A0A669KB34 P15813
PDB IDs			1ZT4 2PO6 3HUJ 3SDX 3TZV 3U0P 3VWJ 3VWK 4EN3 4LHU 4MNG 4MQ7 4WO4 4WW2 4WWK 6V7Y 6V7Z 6V80 8SGB 8SGM 8SOS
Enriched GO Terms of Interacting Partners?		Alpha-beta T Cell Receptor Complex Adaptive Immune Response T Cell Receptor Complex Detection Of Biotic Stimulus Detection Of Bacterium T Cell Receptor Binding T Cell Receptor Signaling Pathway Positive Regulation Of Immune Response Gamma-delta T Cell Receptor Complex Antigen Receptor-mediated Signaling Pathway Immune Response External Side Of Plasma Membrane Antigen Processing And Presentation Of Endogenous Antigen T Cell Selection Regulation Of Immune Response Alpha-beta T Cell Activation Positive Regulation Of Immune System Process Positive Regulation Of T Cell Mediated Cytotoxicity Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of T Cell Mediated Cytotoxicity Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Thymic T Cell Selection Immune System Process Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive T Cell Selection Immune Response-activating Signaling Pathway Positive Regulation Of Cell Killing Positive Regulation Of T Cell Mediated Immunity Immune Response-regulating Signaling Pathway Gamma-delta T Cell Activation Activation Of Immune Response Thymic T Cell Selection Regulation Of Immune System Process Regulation Of Leukocyte Mediated Cytotoxicity Antigen Processing And Presentation Detection Of Stimulus Regulation Of T Cell Mediated Immunity Lumenal Side Of Endoplasmic Reticulum Membrane TAP Binding T Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains T Cell Activation Peptide Antigen Binding Positive Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of Adaptive Immune Response Antigen Processing And Presentation Of Exogenous Antigen Protection From Natural Killer Cell Mediated Cytotoxicity Response To Bacterium Regulation Of T Cell Proliferation Immune Response To Tumor Cell	Protein Folding Protein Folding In Endoplasmic Reticulum Endoplasmic Reticulum Lumen External Side Of Plasma Membrane Lumenal Side Of Endoplasmic Reticulum Membrane Positive Regulation Of Endocytosis Positive Regulation Of Cell Adhesion Extracellular Exosome MHC Class I Peptide Loading Complex Regulation Of Endocytosis Peptide Antigen Assembly With MHC Class I Protein Complex Endoplasmic Reticulum Regulation Of Cell Adhesion Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Positive Thymic T Cell Selection Negative Thymic T Cell Selection Regulation Of Immune System Process Negative T Cell Selection Lymphocyte Mediated Immunity Positive T Cell Selection Positive Regulation Of Viral Entry Into Host Cell MHC Class II Protein Complex Focal Adhesion Heparan Sulfate Proteoglycan Binding Regulation Of Cell Migration Endocytic Vesicle Lumen T Cell Mediated Cytotoxicity Leukocyte Mediated Immunity Regulation Of Cell Motility Positive Regulation Of Immune System Process Positive Regulation Of Leukocyte Migration Regulation Of Viral Entry Into Host Cell Thymic T Cell Selection Regulation Of Locomotion Response To Stress Protein Transport Endoplasmic Reticulum Quality Control Compartment Positive Regulation Of Viral Life Cycle MHC Class II Protein Complex Binding Regulation Of Vesicle-mediated Transport Negative Regulation Of Multicellular Organismal Process Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Cell Migration Antigen Processing And Presentation Of Endogenous Antigen T Cell Selection Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Production Of Molecular Mediator Of Immune Response Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
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