TAF7 and TAF12

Number of citations of the paper that reports this interaction (PubMedID 14580349)
0

Data Source:
HPRD (in vitro, in vivo)

		TAF7	TAF12
Description		TATA-box binding protein associated factor 7	TATA-box binding protein associated factor 12
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GO Annotations	Cellular Component	Male Germ Cell Nucleus Nucleus Nucleoplasm Transcription Regulator Complex Transcription Factor TFIID Complex Cytoplasm Transcription Factor TFTC Complex MLL1 Complex	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFTC Complex
	Molecular Function	Transcription Cis-regulatory Region Binding TFIIH-class Transcription Factor Complex Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Histone Acetyltransferase Binding Nuclear Vitamin D Receptor Binding Nuclear Thyroid Hormone Receptor Binding Protein Heterodimerization Activity Histone H3K27me3 Reader Activity P-TEFb Complex Binding DNA-binding Transcription Factor Binding	DNA Binding Transcription Coactivator Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity DNA-binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Spermine Transport Regulation Of DNA Repair Chromatin Organization DNA-templated Transcription Initiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity Estrogen Receptor Signaling Pathway MRNA Transcription By RNA Polymerase II Negative Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of MHC Class II Biosynthetic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II	Regulation Of DNA Repair DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter MRNA Transcription By RNA Polymerase II Regulation Of RNA Splicing Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome HATs acetylate histones RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Mean platelet volume ( 27863252 32888494) Refractive error ( 32231278)	Type 2 diabetes ( 31049640)
Interacting Genes		28 interacting genes: AHR CDK7 CDK9 CPSF1 FAU GATA1 H3-4 HSF1 IKBKG MAP1LC3B OGT RBM6 SETD7 TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF5 TAF6 TAF8 TAF9 TRIM22 TRIM24 YWHAE ZSCAN1	24 interacting genes: ARID1A ATF7 CLIC6 CPSF1 H3-4 MYC NFYA NFYB NFYC PRKAR2B TAF1 TAF10 TAF11 TAF15 TAF1A TAF2 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBP UBE2I
Entrez ID		6879	6883
HPRD ID		07196	15981
Ensembl ID		ENSG00000178913	ENSG00000120656
Uniprot IDs		Q15545	A0A804HLG9 Q16514
PDB IDs		4RGW 5FUR 6MZL 6MZM 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGH 7EGI 7EGJ 7ENA 7ENC 8GXQ 8GXS 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS	1H3O 6MZC 6MZD 6MZL 6MZM 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGF 7EGG 7EGI 7EGJ 7ENA 7ENC 7KTR 7KTS 8GXQ 8GXS 8H7G 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS
Enriched GO Terms of Interacting Partners?		DNA-templated Transcription Initiation Transcription Initiation At RNA Polymerase II Promoter Transcription Factor TFIID Complex RNA Polymerase II General Transcription Initiation Factor Activity MRNA Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly MRNA Transcription Transcription Preinitiation Complex Assembly Transcription By RNA Polymerase II Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Transcription Factor TFTC Complex DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Protein-DNA Complex Assembly Positive Regulation Of Nucleobase-containing Compound Metabolic Process Protein Heterodimerization Activity Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA Repair RNA Metabolic Process MRNA Metabolic Process Nucleoplasm Positive Regulation Of Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Biosynthetic Process Regulation Of RNA Metabolic Process Nucleus Protein-containing Complex Organization Positive Regulation Of Macromolecule Metabolic Process Protein-containing Complex Assembly Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Stress Positive Regulation Of Metabolic Process Nucleic Acid Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of DNA Metabolic Process Macromolecule Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process SAGA Complex Regulation Of Primary Metabolic Process TBP-class Protein Binding	Transcription Factor TFIID Complex Positive Regulation Of Transcription Initiation By RNA Polymerase II RNA Polymerase II General Transcription Initiation Factor Activity Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II MRNA Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Regulation Of DNA-templated Transcription Initiation MRNA Transcription Transcription Preinitiation Complex Assembly DNA-templated Transcription Initiation Transcription Initiation At RNA Polymerase II Promoter Transcription By RNA Polymerase II Protein-DNA Complex Assembly DNA-templated Transcription Transcription Factor TFTC Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Nucleobase-containing Compound Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleoplasm MRNA Metabolic Process Protein Heterodimerization Activity RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein-containing Complex Organization MLL1 Complex Regulation Of DNA Repair Regulation Of RNA Metabolic Process Transcription Cis-regulatory Region Binding Positive Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process DNA Binding Positive Regulation Of Metabolic Process Regulation Of DNA Metabolic Process Regulation Of Cellular Response To Stress CCAAT-binding Factor Complex Protein-containing Complex Assembly Nucleus Nucleobase-containing Compound Metabolic Process Aryl Hydrocarbon Receptor Binding Regulation Of Gene Expression
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