BSG and SLC16A3

Number of citations of the paper that reports this interaction (PubMedID 10921872)
54

Data Source:
HPRD (in vivo)

		BSG	SLC16A3
Description		basigin (Ok blood group)	solute carrier family 16 member 3
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Photoreceptor Outer Segment Photoreceptor Inner Segment Acrosomal Membrane Mitochondrion Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Focal Adhesion Membrane Basolateral Plasma Membrane Axon Sarcolemma Melanosome Cell Projection Extracellular Exosome	Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Nuclear Membrane Apical Part Of Cell
	Molecular Function	Virus Receptor Activity Protein Binding D-mannose Binding Carbohydrate Binding Signaling Receptor Activity Cadherin Binding Cell-cell Adhesion Mediator Activity	RNA Binding Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Lactate Transmembrane Transporter Activity Symporter Activity Lactate:proton Symporter Activity Transmembrane Transporter Activity Pyruvate Transmembrane Transporter Activity
	Biological Process	Angiogenesis Neural Retina Development Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell Surface Receptor Signaling Pathway Axon Guidance Embryo Implantation Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Endothelial Cell Migration Neutrophil Chemotaxis Positive Regulation Of Interleukin-6 Production Odontogenesis Of Dentin-containing Tooth Response To Peptide Hormone Photoreceptor Cell Maintenance Positive Regulation Of Viral Entry Into Host Cell Response To Mercury Ion Decidualization Symbiont Entry Into Host Cell Response To CAMP Endothelial Tube Morphogenesis Dendrite Self-avoidance Protein Localization To Plasma Membrane Positive Regulation Of Matrix Metallopeptidase Secretion Neuron Projection Extension	Monocarboxylic Acid Transport Lactate Transport Lactate Transmembrane Transport Plasma Membrane Lactate Transport Pyruvate Catabolic Process Transmembrane Transport Pyruvate Transmembrane Transport
Pathways		Degradation of the extracellular matrix Basigin interactions Integrin cell surface interactions Proton-coupled monocarboxylate transport Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) Aspirin ADME	Basigin interactions Proton-coupled monocarboxylate transport
Drugs			Pyruvic acid
Diseases
GWAS		Alzheimer's disease (late onset) ( 28714976)	Hemoglobin ( 32888494) Proteinuria and chronic kidney disease ( 26420894) Refractive error ( 32231278)
Interacting Genes		21 interacting genes: ADRB2 AQP6 CACNA1C CAV1 CCR4 CHRM3 CRBN F2RL1 HGS MMP1 OGT PDLIM7 PPIA PPIL2 PPP2R1B SLC16A1 SLC16A13 SLC16A3 SLC2A4 TMEM14B UBC	10 interacting genes: BANP BSG CDC42 FAM9B GJA8 HDAC7 HPCA NR2C2AP UBQLN1 UBQLN2
Entrez ID		682	9123
HPRD ID		00176	04854
Ensembl ID		ENSG00000172270	ENSG00000141526
Uniprot IDs		P35613 Q54A51	O15427
PDB IDs		3B5H 3I84 3I85 3QQN 3QR2 4U0Q 5X0T 5XF0 6LYY 6LZ0 7CKO 7CKR 7DA5 7DAA 7DCE 7XY8 8XEJ
Enriched GO Terms of Interacting Partners?		Monocarboxylic Acid Transmembrane Transporter Activity Lactate:proton Symporter Activity Vascular Process In Circulatory System Plasma Membrane Lactate Transport Pyruvate Transmembrane Transport Pyruvate Transport Lactate Transmembrane Transporter Activity Regulation Of Muscle Contraction Regulation Of Transport Regulation Of Smooth Muscle Contraction Circulatory System Process Receptor-mediated Endocytosis Positive Regulation Of Cytosolic Calcium Ion Concentration Transmembrane Transporter Activity Lactate Transport Pyruvate Catabolic Process Lactate Transmembrane Transport Regulation Of Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Protein Ubiquitination Positive Regulation Of Cell Communication Positive Regulation Of Signaling Membrane Negative Regulation Of Post-translational Protein Modification Basolateral Plasma Membrane Regulation Of Muscle System Process System Process Symporter Activity Positive Regulation Of Cold-induced Thermogenesis Regulation Of Protein Secretion Positive Regulation Of Cellular Component Biogenesis Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Signal Transduction Positive Regulation Of Secretion By Cell Regulation Of System Process Regulation Of Cardiac Muscle Cell Action Potential Negative Regulation Of Receptor Signaling Pathway Via STAT Positive Regulation Of Secretion Regulation Of Secretion By Cell Monocarboxylic Acid Transport Brown Fat Cell Differentiation Import Into Cell Blood Vessel Diameter Maintenance Regulation Of Cell Communication Positive Regulation Of Protein-containing Complex Disassembly G Protein-coupled Receptor Activity Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Apical Plasma Membrane Ligand-gated Ion Channel Signaling Pathway Regulation Of Cold-induced Thermogenesis Regulation Of Tube Size	Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Transport GBD Domain Binding Storage Vacuole Regulation Of Endocytosis Regulation Of Receptor Internalization Regulation Of Transmembrane Transporter Activity Response To Ketamine Regulation Of Monoatomic Ion Transmembrane Transporter Activity Autophagosome Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Assembly ERAD Pathway Negative Regulation Of G Protein-coupled Receptor Internalization Negative Regulation Of Store-operated Calcium Channel Activity Positive Regulation Of Matrix Metallopeptidase Secretion Endothelin Receptor Signaling Pathway Involved In Heart Process Kinase Binding Autophagosome Organization Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Endothelial Cell Migration Apolipoprotein A-I Receptor Binding Neuropilin Signaling Pathway Identical Protein Binding Response To Aroclor 1254 Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Clathrin-dependent Endocytosis Positive Regulation Of Proteasomal Protein Catabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?