SSX2 and FTSJ3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SSX2	FTSJ3
Description		SSX family member 2	FtsJ RNA 2'-O-methyltransferase 3
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GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Chromosome Nucleolus Preribosome, Large Subunit Precursor Preribosome, Small Subunit Precursor
	Molecular Function	Protein Binding	RNA Binding Protein Binding Methyltransferase Activity RRNA Methyltransferase Activity RRNA (uridine-2'-O-)-methyltransferase Activity RRNA (guanine) Methyltransferase Activity Transferase Activity RNA 2'-O-methyltransferase Activity
	Biological Process	Regulation Of DNA-templated Transcription	Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RNA Methylation RRNA Processing RRNA Methylation Methylation Ribosome Biogenesis
Pathways			Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases		Synovial sarcoma
GWAS			Hemoglobin levels ( 32327693)
Interacting Genes		17 interacting genes: AKAP9 BLZF1 FLACC1 FTSJ3 KRT40 LRRC45 MAGEC2 PHLDA2 RAB3IP RNF2 SSX2IP SYCE1 TAX1BP1 TNPO3 TRAPPC2L ZBED1 ZMIZ2	12 interacting genes: CSNK2A1 EIF2AK2 EIF4ENIF1 FANCG MAGEB4 OAS3 OGT RNF10 SAT1 SNW1 SSX2 SSX2B
Entrez ID		6757	117246
HPRD ID		02180	17024
Ensembl ID		ENSG00000241476	ENSG00000108592
Uniprot IDs		Q16385 R9QTR3	Q8IY81
PDB IDs		8HQY	8FKP 8FKQ 8FKR 8FKS 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY 8IR1
Enriched GO Terms of Interacting Partners?		SUMO Ligase Activity	Negative Regulation Of Translation Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Translational Initiation Sin3-type Complex Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Nucleus Regulation Of Translation Regulation Of Gene Expression Regulation Of DNA-templated Transcription Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Metabolic Process Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Translational Initiation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Transferase Activity Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Protein Metabolic Process Negative Regulation Of Chemokine (C-X-C Motif) Ligand 9 Production Negative Regulation Of Viral Genome Replication Spermidine Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Negative Regulation Of Proteasomal Protein Catabolic Process Membraneless Organelle Assembly Regulation Of Metabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Gene Expression Negative Regulation Of Metabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Double-stranded RNA Binding Antiviral Innate Immune Response Regulation Of Viral Genome Replication Negative Regulation Of Viral Process Positive Regulation Of Chemokine Production Spermidine Acetylation Putrescine Catabolic Process Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Translation Protein Localization To Vacuole Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Catabolic Process Diamine N-acetyltransferase Activity Protein O-acetylglucosaminyltransferase Activity
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