SRC and EGFR

Number of citations of the paper that reports this interaction (PubMedID 10075741)
0

Data Source:
HPRD (in vitro)

		SRC	EGFR
Description		SRC proto-oncogene, non-receptor tyrosine kinase	epidermal growth factor receptor
Image
GO Annotations	Cellular Component	Podosome Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Lysosome Late Endosome Cytosol Cytoskeleton Actin Filament Plasma Membrane Caveola Cell-cell Junction Focal Adhesion Membrane Cell Junction Ruffle Membrane Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome Anchoring Junction	Golgi Membrane Extracellular Region Extracellular Space Nucleus Cytoplasm Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Plasma Membrane Focal Adhesion Cilium Basal Plasma Membrane Cell Surface Endosome Membrane Membrane Basolateral Plasma Membrane Cell Junction Endocytic Vesicle Clathrin-coated Endocytic Vesicle Membrane Early Endosome Membrane Nuclear Membrane Ruffle Membrane Protein-containing Complex Ciliary Basal Body Receptor Complex Membrane Raft Perinuclear Region Of Cytoplasm Shc-EGFR Complex Multivesicular Body, Internal Vesicle Lumen Intracellular Vesicle
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Signaling Receptor Binding Integrin Binding Protein Binding ATP Binding Phospholipase Activator Activity Kinase Activity Transferase Activity Enzyme Binding Protein Domain Specific Binding Heme Binding Protein Tyrosine Kinase Activator Activity Signaling Receptor Activator Activity Ionotropic Glutamate Receptor Binding SH2 Domain Binding Phospholipase Binding Transmembrane Transporter Binding Cadherin Binding Ephrin Receptor Binding ATPase Binding Phosphoprotein Binding BMP Receptor Binding Connexin Binding Scaffold Protein Binding	Nucleotide Binding Virus Receptor Activity Chromatin Binding Double-stranded DNA Binding Protein Kinase Activity MAP Kinase Kinase Kinase Activity Protein Tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Transmembrane Signaling Receptor Activity Epidermal Growth Factor Receptor Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Enzyme Binding Kinase Binding Protein Phosphatase Binding Protein Tyrosine Kinase Activator Activity Ubiquitin Protein Ligase Binding Identical Protein Binding Cadherin Binding Epidermal Growth Factor Binding Actin Filament Binding ATPase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Stimulatory C-type Lectin Receptor Signaling Pathway Neutrophil Activation Involved In Immune Response Immune System Process Negative Regulation Of Inflammatory Response To Antigenic Stimulus Cell Adhesion Signal Transduction Signal Complex Assembly Epidermal Growth Factor Receptor Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Regulation Of Epithelial Cell Migration Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Protein Processing Macroautophagy Cell Migration Protein Deubiquitination Peptidyl-tyrosine Phosphorylation Regulation Of Cell-cell Adhesion Cell Differentiation Platelet Activation Forebrain Development T Cell Costimulation Negative Regulation Of Protein-containing Complex Assembly Protein Destabilization Cellular Response To Nutrient Levels Negative Regulation Of Telomere Maintenance Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Integrin Activation Toll-like Receptor 3 Signaling Pathway Regulation Of Toll-like Receptor 3 Signaling Pathway Substrate Adhesion-dependent Cell Spreading Cellular Response To Reactive Oxygen Species Positive Regulation Of Dephosphorylation Negative Regulation Of Hippo Signaling Intracellular Signal Transduction Osteoclast Development Cellular Response To Platelet-derived Growth Factor Stimulus Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis ERBB2 Signaling Pathway Angiotensin-activated Signaling Pathway TORC1 Signaling Vasodilation Odontogenesis Negative Regulation Of Apoptotic Process Regulation Of Vascular Permeability Stress Fiber Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Bone Resorption Bone Resorption Positive Regulation Of Notch Signaling Pathway Positive Regulation Of Glycolytic Process Symbiont Entry Into Host Cell Protein Autophosphorylation Vascular Endothelial Growth Factor Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Focal Adhesion Assembly Oogenesis Progesterone Receptor Signaling Pathway Leukocyte Migration Positive Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Focal Adhesion Assembly Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Mitochondrial Depolarization Uterus Development Branching Involved In Mammary Gland Duct Morphogenesis Regulation Of Cell Projection Assembly Intestinal Epithelial Cell Development Interleukin-6-mediated Signaling Pathway Cellular Response To Hydrogen Peroxide Positive Regulation Of ERK1 And ERK2 Cascade Response To Interleukin-1 Cellular Response To Peptide Hormone Stimulus Cellular Response To Progesterone Stimulus Cellular Response To Fluid Shear Stress Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Podosome Assembly Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Heart Rate By Cardiac Conduction Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Protein Localization To Nucleus Negative Regulation Of Neutrophil Activation Negative Regulation Of TORC1 Signaling Positive Regulation Of TORC1 Signaling Positive Regulation Of Lamellipodium Morphogenesis Positive Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Regulation Of Early Endosome To Late Endosome Transport Negative Regulation Of Anoikis Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Caveolin-mediated Endocytosis	MAPK Cascade Cell Morphogenesis Ossification Embryonic Placenta Development Positive Regulation Of Protein Phosphorylation Hair Follicle Development Signal Transduction Cell Surface Receptor Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Salivary Gland Morphogenesis Learning Or Memory Cell Population Proliferation Positive Regulation Of Cell Population Proliferation Epidermis Development Cerebral Cortex Cell Migration Neuron Differentiation Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Positive Regulation Of Peptidyl-serine Phosphorylation ERBB2-EGFR Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cell Population Proliferation Negative Regulation Of Protein Catabolic Process Positive Regulation Of Phosphorylation Negative Regulation Of Apoptotic Process Positive Regulation Of MAPK Cascade Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of DNA Repair Positive Regulation Of DNA Replication Positive Regulation Of Transcription By RNA Polymerase II Symbiont Entry Into Host Cell Positive Regulation Of Fibroblast Proliferation Digestive Tract Morphogenesis Epithelial Cell Proliferation Positive Regulation Of Epithelial Cell Proliferation Regulation Of Peptidyl-tyrosine Phosphorylation Protein Insertion Into Membrane Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Morphogenesis Of An Epithelial Fold Eyelid Development In Camera-type Eye Response To UV-A Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Amino Acid Stimulus Cellular Response To Growth Factor Stimulus Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Estradiol Stimulus Positive Regulation Of Protein Kinase C Signaling Positive Regulation Of Canonical Wnt Signaling Pathway Cell-cell Adhesion Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of MiRNA Transcription Positive Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Cardiocyte Differentiation
Pathways		Signaling by ERBB2 Nuclear signaling by ERBB4 Downregulation of ERBB4 signaling PIP3 activates AKT signaling GAB1 signalosome Downstream signal transduction Constitutive Signaling by Aberrant PI3K in Cancer Integrin signaling GRB2:SOS provides linkage to MAPK signaling for Integrins p130Cas linkage to MAPK signaling for integrins G alpha (s) signalling events G alpha (i) signalling events G alpha (i) signalling events DCC mediated attractive signaling DCC mediated attractive signaling Netrin mediated repulsion signals Regulation of commissural axon pathfinding by SLIT and ROBO RAF activation MAP2K and MAPK activation Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF1 fusions Paradoxical activation of RAF signaling by kinase inactive BRAF PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling MET activates PTK2 signaling InlA-mediated entry of Listeria monocytogenes into host cells Regulation of RUNX1 Expression and Activity RUNX2 regulates osteoblast differentiation Regulation of RUNX3 expression and activity Extra-nuclear estrogen signaling RHOU GTPase cycle Activated NTRK2 signals through FYN Activated NTRK3 signals through PI3K Activated NTRK3 signals through PI3K Long-term potentiation GPER1 signaling Signaling downstream of RAS mutants Signaling by RAF1 mutants Signaling by CSF1 (M-CSF) in myeloid cells Degradation of CDH1	Signaling by ERBB2 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants Signaling by ERBB4 SHC1 events in ERBB2 signaling SHC1 events in ERBB2 signaling PLCG1 events in ERBB2 signaling PIP3 activates AKT signaling Signaling by EGFR GRB2 events in EGFR signaling GAB1 signalosome SHC1 events in EGFR signaling EGFR downregulation GRB2 events in ERBB2 signaling PI3K events in ERBB2 signaling EGFR interacts with phospholipase C-gamma EGFR Transactivation by Gastrin Constitutive Signaling by Aberrant PI3K in Cancer Signal transduction by L1 Constitutive Signaling by EGFRvIII Inhibition of Signaling by Overexpressed EGFR RAF/MAP kinase cascade ERBB2 Regulates Cell Motility PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling ERBB2 Activates PTK6 Signaling Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis PTK6 promotes HIF1A stabilization Downregulation of ERBB2 signaling TFAP2 (AP-2) family regulates transcription of growth factors and their receptors Extra-nuclear estrogen signaling NOTCH3 Activation and Transmission of Signal to the Nucleus HCMV Early Events Estrogen-dependent nuclear events downstream of ESR-membrane signaling Signaling by ERBB2 KD Mutants Signaling by ERBB2 ECD mutants Signaling by ERBB2 TMD/JMD mutants Respiratory syncytial virus (RSV) attachment and entry Developmental Lineage of Mammary Gland Myoepithelial Cells
Drugs		Dasatinib RU84687 RU79256 N6-Benzyl Adenosine-5'-Diphosphate RU85493 RU78262 Phosphonotyrosine Malonic acid RU83876 RU90395 RU79072 RU78783 1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine PASBN 2-[4-[(Z)-2-Acetamido-3-oxo-3-[[(3S)-2-oxo-1-[(4-phenylphenyl)methyl]azepan-3-yl]amino]prop-1-enyl]-2-formylphenyl]acetic acid PAS219 DPI59 RU82197 Phenylphosphate RU78300 RU79073 RU82209 ISO24 RU85053 RU78299 Oxalic Acid RU78191 Citric acid Paratoulene phosphate 4-[(4-METHYL-1-PIPERAZINYL)METHYL]-N-[3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]PHENYL]-BENZAMIDE Purvalanol A XL228 Tirbanibulin Bosutinib 1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea 1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-phenylurea 3-[4-AMINO-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL]PHENOL PD-168393 [4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl}amino)phenyl]acetonitrile PP-121 1-cyclobutyl-3-(3,4-dimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 1-(1-methylethyl)-3-quinolin-6-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine 2-(4-CARCOXY-5-ISOPROPYLTHIAZOLYL)BENZOPIPERIDINE N-(4-PHENYLAMINO-QUINAZOLIN-6-YL)-ACRYLAMIDE (2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide Ponatinib Nintedanib Fostamatinib	Cetuximab Lidocaine Gefitinib Erlotinib Lapatinib Panitumumab Alvocidib IGN311 Matuzumab Vandetanib Rindopepimut Canertinib Pelitinib Varlitinib AV-412 S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE PD-168393 Afatinib Osimertinib Necitumumab Foreskin keratinocyte (neonatal) Depatuxizumab mafodotin Icotinib Neratinib Dacomitinib Fostamatinib Poziotinib Zalutumumab Brigatinib Olmutinib Zanubrutinib Abivertinib Mobocertinib Almonertinib Amivantamab
Diseases			Laryngeal cancer Cervical cancer Oral cancer Gastric cancer Choriocarcinoma Esophageal cancer Glioma Bladder cancer
GWAS		L1-L4 bone mineral density x serum urate levels interaction ( 34046847) Retinopathy in non-diabetics ( 23393555) Rheumatoid arthritis ( 30891314) Squamous cell carcinoma ( 26908436)	Dental caries (decayed and filled deciduous teeth) ( 31533690) Glioblastoma ( 28346443 29743610) Glioblastoma (age-stratified) ( 30152087) Glioma ( 21531791 28346443 29743610) Haemorrhoidal disease ( 33888516) Impulsivity ( 30718321) Initial alcohol sensitivity ( 30276832) L1-L4 bone mineral density x serum urate levels interaction ( 34046847) Mean corpuscular hemoglobin concentration ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Monocyte count ( 32888494) Non-glioblastoma glioma ( 28346443) Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Refractive astigmatism ( 30306274) Subjective response to lithium treatment ( 26503763)
Interacting Genes		312 interacting genes: ABL1 ACTN1 ADAM12 ADAM15 ADRB2 ADRB3 AFAP1 AFAP1L2 AGAP1 AHR AKT1 ALDOB ANKRD11 ANXA1 ANXA2 ANXA7 AR ARHGAP1 ARHGAP17 ARHGAP32 ARHGAP35 ARR3 ASAP1 ATG9A ATP2B4 AXL BAAT BARD1 BCAR1 BCCIP BCR BMX BRMS1 CA3 CASP8 CAV1 CAV2 CBL CBLC CCDC180 CCNA1 CD2AP CD33 CD36 CD44 CD46 CD47 CD59 CDC25A CDCP1 CDH5 CDK1 CDK5 CDKN1B CEACAM1 CEACAM3 CFL1 CHUK CLTC CNTNAP1 COASY CORO7 CRMP1 CSK CTNNB1 CTNND1 CTSV CTTN CUL4B DAB1 DAB2 DAG1 DAPP1 DDR2 DGKA DGKZ DLG4 DNM1 DNM2 DOK1 DOK2 DOK4 DPYD DUSP12 EFNA5 EFNB1 EFNB2 EFS EGFR EGLN1 EMD ENO1 ENPP7 EPHA3 EPHA4 EPHB2 EPS8 ERBB2 ERBB3 ERBB4 ERRFI1 ESR1 ESR2 ETS1 ETS2 EVL FANCC FARP2 FASLG FBP2 FBXO5 FGR FHIT FLNA FLT3 FMR1 FOXO1 FRS2 FYB1 FZR1 GAB1 GAB2 GAB3 GALNT12 GFAP GIT1 GJA1 GJB1 GRB10 GRB2 GRIN2A GRIN2B GRK2 GTF2I GUCY2C HDAC3 HEMGN HLA-A HLA-B HNF1A HNRNPK HRAS HSP90AA1 IGF1R IKBKB IKBKG IL6R INPPL1 INSR ITGB3 ITK JUP KCNA5 KCNB1 KCNQ5 KDR KHDRBS1 KIFAP3 KIT LATS2 LRP1 MAP2 MAP2K1 MAPK15 MAPK3 MAPK8IP3 MAPRE1 MAPT MATK MDM2 MED28 MET MICAL1 MPZL1 MST1R MT-ND2 MUC1 MYLK NANS NCOA6 NEDD4 NFKBIA NMT1 NOS2 NPHS1 NR1I2 NR1I3 NR3C1 P2RY2 PAK2 PDCD6IP PDE4D PDE6G PDGFRB PDPK1 PECAM1 PELP1 PGR PI3 PIK3R1 PIK3R3 PIP5K1C PKD1 PLCG1 PLD1 PLD2 PLSCR1 PLTP PPARD PPARGC1B PPP2CB PRKACA PRKCA PRKCD PRKCE PRKCH PRKCI PRKCZ PRKD1 PROM1 PTK2 PTK2B PTPA PTPN1 PTPN11 PTPN18 PTPN2 PTPN21 PTPN6 PTPRA PTPRC PTPRE PTPRT PXN RACK1 RAF1 RARA RASA1 RASGRF1 RET RGS16 RPL10 RPS6KA3 RPS6KB1 RPS6KB2 RXRA SH2D3C SH3BP1 SH3PXD2A SHB SHC1 SKAP1 SKAP2 SLC9A2 SMARCB1 SMARCE1 SNCA SOCS1 SORBS1 SPTAN1 SRCIN1 SRF SRPK2 STAP2 STAT1 STAT3 STAT5A STAT5B STAT6 STUB1 STX17 SYK SYN1 TAMALIN TERT THRA THRB TIAM1 TMPO TNFRSF11A TNFRSF1A TNK2 TP53 TRAF1 TRAF3 TRAF6 TRAT1 TRIM50 TRIM7 TRIP10 TRIP6 TRPC6 TRPV4 TUB TXK TYRO3 USP8 VCL VDR VIL1 WAS WASL WBP11 WWOX XPA YTHDC1 YWHAB YWHAE YWHAG YWHAH ZNF189 ZNF687	416 interacting genes: ABL2 ACTA1 ADRM1 AGTR1 AHNAK AHSA1 AIP AKAP12 ALCAM AMH AMPH ANKS1A ANKS1B ANXA1 AOPEP APBA3 APBB1 APBB3 APP APPL1 AR AREG ARF4 ARHGEF12 ARHGEF7 ARRB2 ATP1A1 ATP1B1 ATP5F1C AXL B4GALT1 BAIAP2 BCAR3 BLK BLNK BMX BTC CALM1 CALM2 CALM3 CAMK2A CAMK2G CAMLG CASP1 CAV1 CAV2 CAV3 CBL CBLB CBLC CCDC88A CD44 CD82 CDC25A CDC34 CDH1 CDH5 CEACAM1 CEBPB CEND1 CLNK CLTA CLTCL1 CMTM8 CNOT9 CNTN2 COL9A3 CRK CSRP1 CTNNB1 CTNND1 CTTN CYLC2 DCBLD2 DCN DCTN2 DDX17 DEGS1 DIAPH1 DNAJC4 DOK2 DOK4 DOK5 DOK6 DUSP19 DUSP3 DYNC1H1 EGF ELF3 EPB41 EPHA2 EPPK1 EPS15 EPS8 ERBB2 ERBB3 ERBB4 EREG ERRFI1 ESR1 EZR FAH FANCC FAS FBXL2 FBXO25 FER FES FGR FKBP4 FKBP8 FN1 FNDC3B FRAT2 FRK GAB1 GABARAPL2 GAPDH GGA1 GGA3 GJB1 GNAI2 GNAS GOT1 GPM6B GPNMB GRAP2 GRB10 GRB14 GRB2 GRB7 GRIN2B GRK2 H3-4 HBEGF HCK HDAC7 HEBP1 HEMGN HEXIM1 HGS HOXC10 HPN HSH2D HSP90AA1 HSP90AB1 HSP90B1 HSPA1A HSPA4 HSPA8 HTT ICAM1 IKBKG IL13RA2 IL5RA ILKAP INPPL1 IQGAP1 IRS1 IRS4 ITGA5 ITGB1 ITGB2 ITK ITSN2 JAK2 JUP KCTD9P2 KEAP1 KRT17 KRT18 KRT7 KRT8 LAT LCK LCP2 LINC01139 LRP1 LRRK1 LYN MAP2K1 MAP3K12 MAP3K14 MAP3K3 MAP4K1 MAPK1 MAPK14 MAPK3 MAPK8 MAPK8IP1 MAPK8IP2 MAPK9 MAPT MAST1 MATR3 MDH1 MEGF6 MET MGARP MIF MOB4 MT-CO2 MTDH MUC1 MUC4 NANS NCAM1 NCK1 NCK2 NDN NEDD4 NF2 NHERF1 NIBAN2 NR3C1 NRG1 NTRK2 NUMB NUMBL OAZ1 OLFM1 PAK1 PCNA PDCD6IP PDGFRA PDGFRB PDK3 PDP1 PELI1 PFKP PHKG1 PIK3C2A PIK3C2B PIK3CA PIK3R1 PIK3R2 PIK3R3 PIM1 PIN4 PITPNA PKIA PLCG1 PLCG2 PLD1 PLD2 PLEC PLSCR1 PML POM121L12 PPARG PPM1A PPM1B PPP2CB PPP3CB PPP5C PRCC PRDX1 PRKACA PRKAR1A PRKAR1B PRKCA PRKCB PRKCD PRKCE PRKCZ PRKD1 PSMA7 PSMD4 PTGDS PTK2 PTK2B PTK6 PTPN1 PTPN11 PTPN12 PTPN18 PTPN2 PTPN20 PTPN22 PTPN6 PTPN7 PTPRB PTPRH PTPRJ PTPRR PTPRS PTPRT PTPRU RAB31 RAB3A RAP1GDS1 RAPGEF1 RASA1 RGS16 RGS2 RGS4 RIMS2 RIN1 RIN2 RIPK1 RNF115 RNF126 RNF128 RNF130 RNF144A RNF167 RRAD RUSC2 S100A4 S100A7 S100A9 SCAMP1 SCAMP3 SEC13 SELENOP SFN SGSM2 SH2B1 SH2B2 SH2B3 SH2D1A SH2D1B SH2D2A SH2D3A SH2D3C SH3BGRL3 SH3GL3 SHB SHC1 SHC2 SHC3 SHC4 SHD SHE SLA SLA2 SLC3A2 SLC9D1 SMURF2 SNCA SNRPD2 SNX1 SNX2 SNX4 SNX6 SNX9 SOCS1 SOCS2 SOCS3 SOCS4 SOCS5 SOCS6 SOCS7 SORBS2 SOS1 SOS2 SPARCL1 SPCS2 SRC STAG3L4 STAM2 STAMBP STAP1 STAP2 STAT1 STAT2 STAT3 STAT5A STAT5B STIP1 STUB1 STX17 STYX SUPT6H SYK TAB1 TEC TGFA TGFB1 TJP1 TLN1 TLR2 TNC TNFRSF1A TNK2 TNS1 TNS2 TNS3 TNS4 TPI1 TPM1 TRAF2 TRMO TRPV1 TSTD2 TUBA1A TUBA4A TXK TXN UBB UBE2V2 UROD VAPA VAV1 VAV2 VAV3 WASF3 WASL XRCC6 YES1 YWHAB YWHAQ YWHAZ ZAP70 ZNF510 ZPR1
Entrez ID		6714	1956
HPRD ID		01819	00579
Ensembl ID		ENSG00000197122	ENSG00000146648
Uniprot IDs		P12931	B7Z2I3 C9JYS6 E7BSV0 F2YGG7 P00533 Q504U8
PDB IDs		1A07 1A08 1A09 1A1A 1A1B 1A1C 1A1E 1FMK 1HCS 1HCT 1KSW 1O41 1O42 1O43 1O44 1O45 1O46 1O47 1O48 1O49 1O4A 1O4B 1O4C 1O4D 1O4E 1O4F 1O4G 1O4H 1O4I 1O4J 1O4K 1O4L 1O4M 1O4N 1O4O 1O4P 1O4Q 1O4R 1SHD 1Y57 1YI6 1YOJ 1YOL 1YOM 2BDF 2BDJ 2H8H 2SRC 3VRO 3ZMP 3ZMQ 4F59 4F5A 4F5B 4HXJ 4K11 4MXO 4MXX 4MXY 4MXZ 6ATE 6C4S 6E6E 6EHJ 7NG7 7OTE 7T1U 7YQE 8GWH 8HAQ 8JF3 8JN8 8JN9 8VCF 8VCG	1IVO 1M14 1M17 1MOX 1NQL 1XKK 1YY9 1Z9I 2EB2 2EB3 2GS2 2GS6 2GS7 2ITN 2ITO 2ITP 2ITQ 2ITT 2ITU 2ITV 2ITW 2ITX 2ITY 2ITZ 2J5E 2J5F 2J6M 2JIT 2JIU 2JIV 2KS1 2M0B 2M20 2N5S 2RF9 2RFD 2RFE 2RGP 3B2U 3B2V 3BEL 3BUO 3C09 3G5V 3G5Y 3GOP 3GT8 3IKA 3LZB 3NJP 3OB2 3OP0 3P0Y 3PFV 3POZ 3QWQ 3UG1 3UG2 3VJN 3VJO 3VRP 3VRR 3W2O 3W2P 3W2Q 3W2R 3W2S 3W32 3W33 4G5J 4G5P 4HJO 4I1Z 4I20 4I21 4I22 4I23 4I24 4JQ7 4JQ8 4JR3 4JRV 4KRL 4KRM 4KRO 4KRP 4LI5 4LL0 4LQM 4LRM 4R3P 4R3R 4R5S 4RIW 4RIX 4RIY 4RJ4 4RJ5 4RJ6 4RJ7 4RJ8 4TKS 4UIP 4UV7 4WD5 4WKQ 4WRG 4ZAU 4ZJV 4ZSE 5C8K 5C8M 5C8N 5CAL 5CAN 5CAO 5CAP 5CAQ 5CAS 5CAU 5CAV 5CNN 5CNO 5CZH 5CZI 5D41 5EDP 5EDQ 5EDR 5EM5 5EM6 5EM7 5EM8 5FED 5FEE 5FEQ 5GMP 5GNK 5GTY 5GTZ 5HCX 5HCY 5HCZ 5HG5 5HG7 5HG8 5HG9 5HIB 5HIC 5J9Y 5J9Z 5JEB 5LV6 5SX4 5SX5 5U8L 5UG8 5UG9 5UGA 5UGB 5UGC 5UWD 5WB7 5WB8 5X26 5X27 5X28 5X2A 5X2C 5X2F 5X2K 5XDK 5XDL 5XGM 5XGN 5XWD 5Y25 5Y9T 5YU9 5ZTO 5ZWJ 6ARU 6B3S 6D8E 6DUK 6JRJ 6JRK 6JRX 6JWL 6JX0 6JX4 6JXT 6JZ0 6LUB 6LUD 6P1D 6P1L 6P8Q 6S89 6S8A 6S9B 6S9C 6S9D 6TFU 6TFV 6TFW 6TFY 6TFZ 6TG0 6TG1 6V5N 6V5P 6V66 6V6K 6V6O 6VH4 6VHN 6VHP 6WA2 6WAK 6WXN 6XL4 6Z4B 6Z4D 7A2A 7A6I 7A6J 7A6K 7AEI 7AEM 7B85 7ER2 7JXI 7JXK 7JXL 7JXM 7JXP 7JXQ 7JXW 7K1H 7K1I 7KXZ 7KY0 7LEN 7LFR 7LFS 7LG8 7LGS 7LTX 7OM4 7OXB 7SI1 7SYD 7SYE 7SZ0 7SZ1 7SZ5 7SZ7 7T4I 7T4J 7TVD 7U98 7U99 7U9A 7UKV 7UKW 7VRA 7VRE 7ZYM 7ZYN 7ZYP 7ZYQ 8A27 8A2A 8A2B 8A2D 8D73 8D76 8DSW 8EME 8F1H 8F1W 8F1X 8F1Y 8F1Z 8FV3 8FV4 8G63 8GB4 8GK5 8H7X 8HGO 8HGP 8HGS 8HV1 8HV2 8HV3 8HV4 8HV5 8HV6 8HV7 8HV8 8HV9 8HVA 8HY7 8KFQ 8PNZ 8PO0 8PO1 8PO2 8PO3 8PO4 8S1M 8SC7 8TJL 8TO3 8TO4 8UKV 8UKW 8UKX 8WD4 9D3V 9D3W 9EWS 9EWT 9FQP 9FQS 9FRD 9GC4 9GC5 9GC6 9GDV 9H46 9HBO
Enriched GO Terms of Interacting Partners?		Signal Transduction Cell Surface Receptor Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Signaling Plasma Membrane Regulation Of Cell Communication Regulation Of Signal Transduction Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Multicellular Organismal Process Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Regulation Of Cellular Component Organization Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Signaling Cytosol Cytoplasm Regulation Of Developmental Process Positive Regulation Of Cell Communication Regulation Of Transport Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Metabolic Process Intracellular Signaling Cassette Developmental Process Positive Regulation Of Macromolecule Metabolic Process Focal Adhesion Protein Kinase Activity Protein Tyrosine Kinase Activity Negative Regulation Of Programmed Cell Death Kinase Activity Regulation Of Cell Population Proliferation Regulation Of Locomotion Negative Regulation Of Signaling Negative Regulation Of Apoptotic Process Cellular Response To Oxygen-containing Compound Negative Regulation Of Cell Communication Regulation Of MAPK Cascade Regulation Of Cell Adhesion Regulation Of Multicellular Organismal Development Regulation Of Immune System Process Positive Regulation Of Biosynthetic Process Regulation Of Cell Motility Regulation Of Cell Migration Negative Regulation Of Signal Transduction Regulation Of Cell Differentiation Regulation Of Biological Quality Positive Regulation Of Immune System Process Phosphorylation	Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway Cell Surface Receptor Signaling Pathway Signal Transduction Regulation Of Signal Transduction Regulation Of Signaling Phosphotyrosine Residue Binding Regulation Of Cell Communication Cytosol Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Positive Regulation Of Signaling Positive Regulation Of Signal Transduction Positive Regulation Of Cell Communication Cytoplasm ERBB Signaling Pathway Plasma Membrane Positive Regulation Of Intracellular Signal Transduction Regulation Of MAPK Cascade Epidermal Growth Factor Receptor Signaling Pathway Epidermal Growth Factor Receptor Binding Regulation Of Immune Response Regulation Of Immune System Process Intracellular Signaling Cassette Negative Regulation Of Signal Transduction Regulation Of Transport Regulation Of Multicellular Organismal Process Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Cellular Component Organization Regulation Of Defense Response Non-membrane Spanning Protein Tyrosine Kinase Activity Focal Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Immune Response Positive Regulation Of Immune System Process Protein Tyrosine Kinase Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Protein Kinase Binding Positive Regulation Of MAPK Cascade Regulation Of Cell Adhesion Protein Kinase Activity ERBB2 Signaling Pathway Regulation Of Biological Quality Regulation Of Innate Immune Response Insulin Receptor Signaling Pathway Regulation Of Programmed Cell Death Kinase Activity Regulation Of Apoptotic Process Activation Of Immune Response
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