SNTA1 and SLC2A3

Number of citations of the paper that reports this interaction (PubMedID 15123239)
0

Data Source:
BioGRID (unspecified method)

		SNTA1	SLC2A3
Description		syntrophin alpha 1	solute carrier family 2 member 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Syntrophin Complex Membrane Lateral Plasma Membrane Neuromuscular Junction Protein-containing Complex Sarcolemma Anchoring Junction	Plasma Membrane Membrane Aggresome Secretory Granule Membrane Specific Granule Membrane Cell Projection Perikaryon Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Transmembrane Transporter Binding Nitric-oxide Synthase Binding ATPase Binding	Fructose Transmembrane Transporter Activity Galactose Transmembrane Transporter Activity Protein Binding D-glucose Binding Transmembrane Transporter Activity Dehydroascorbic Acid Transmembrane Transporter Activity D-glucose Transmembrane Transporter Activity
	Biological Process	Regulation Of Heart Rate Muscle Contraction Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Regulation Of Sodium Ion Transmembrane Transport	Carbohydrate Metabolic Process Fructose Transmembrane Transport Galactose Transmembrane Transport L-ascorbic Acid Metabolic Process D-glucose Import Transmembrane Transport Dehydroascorbic Acid Transport D-glucose Import Across Plasma Membrane Transport Across Blood-brain Barrier D-glucose Transmembrane Transport
Pathways		Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)	Cellular hexose transport Vitamin C (ascorbate) metabolism Neutrophil degranulation MECP2 regulates neuronal receptors and channels
Drugs
Diseases		Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS		HDL cholesterol x physical activity interaction (1df test) ( 30670697) HDL cholesterol x physical activity interaction (2df test) ( 30670697)	Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971)
Interacting Genes		76 interacting genes: ABCA1 ABCC4 ACTA2 ADAMTS6 ADGRB1 ADGRB2 ADGRB3 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA DTNB ENTREP3 F8A1 FABP1 GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 RPS6KA1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TIAM1 TLX3 TRA TRBV12-3 UTRN VANGL2 XRCC6	6 interacting genes: CREB3 CREB3L1 GOLGB1 MTNR1A MTNR1B SNTA1
Entrez ID		6640	6515
HPRD ID		03009	00686
Ensembl ID		ENSG00000101400	ENSG00000059804
Uniprot IDs		B3KTR0 Q13424	P11169
PDB IDs			4ZW9 4ZWB 4ZWC 5C65 7CRZ 7SPS 7SPT
Enriched GO Terms of Interacting Partners?		Plasma Membrane System Process Regulation Of System Process Membrane G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Activity Regulation Of Blood Circulation Circulatory System Process Vascular Process In Circulatory System Monoatomic Ion Channel Complex Regulation Of Multicellular Organismal Process Regulation Of Heart Contraction Blood Vessel Diameter Maintenance Regulation Of Tube Size Basolateral Plasma Membrane Monoatomic Ion Transmembrane Transport Regulation Of Biological Quality Transmembrane Transport Muscle Contraction Inorganic Ion Transmembrane Transport Metal Ion Transport Monoatomic Ion Transport Regulation Of Heart Rate Inorganic Cation Transmembrane Transport Regulation Of Membrane Potential Monoatomic Cation Transmembrane Transport Monoatomic Cation Transport Cardiac Muscle Cell Action Potential Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Muscle System Process Synapse Inward Rectifier Potassium Channel Activity Synaptic Signaling Vasodilation Intracellular Signaling Cassette Regulation Of Monoatomic Ion Transmembrane Transport Adrenergic Receptor Activity CGMP-mediated Signaling Calcium-mediated Signaling Action Potential Potassium Ion Transport Regulation Of Blood Pressure Regulation Of Muscle Contraction Regulation Of Monoatomic Ion Transport Voltage-gated Sodium Channel Complex Signal Transduction Angiotensin-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Multicellular Organismal Process	Melatonin Receptor Activity Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Negative Regulation Of Response To Endoplasmic Reticulum Stress Endoplasmic Reticulum Unfolded Protein Response Response To Unfolded Protein Positive Regulation Of Deacetylase Activity Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Protein Localization To Pericentriolar Material Extracellular Matrix Constituent Secretion Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Regulation Of Neuronal Action Potential Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Syntrophin Complex CCR1 Chemokine Receptor Binding Release From Viral Latency Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of Transmission Of Nerve Impulse Negative Regulation Of Programmed Cell Death Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Blood Circulation CAMP Response Element Binding Protein Binding Membrane Nitric-oxide Synthase Binding CAMP Response Element Binding Negative Regulation Of Vasoconstriction Regulation Of CGMP-mediated Signaling Hormone Binding Regulation Of Transmission Of Nerve Impulse Negative Regulation Of Cytosolic Calcium Ion Concentration Dystrophin-associated Glycoprotein Complex Ventricular Cardiac Muscle Cell Action Potential Regulation Of Metal Ion Transport Induction Of Positive Chemotaxis Protein Localization To Centrosome G Protein-coupled Receptor Activity Mating Behavior Negative Regulation Of Signal Transduction Positive Regulation Of Circadian Rhythm Negative Regulation Of Nervous System Process Regulation Of Membrane Potential Regulation Of Circadian Sleep/wake Cycle, Sleep
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