GINS3 and KRT80

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GINS3	KRT80
Description		GINS complex subunit 3	keratin 80
Image			No pdb structure
GO Annotations	Cellular Component	GINS Complex Nucleus Nucleoplasm Chromosome CMG Complex	Cytoplasm Cytosol Intermediate Filament Desmosome Keratin Filament Intermediate Filament Cytoskeleton
	Molecular Function	Protein Binding	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	DNA Replication Multicellular Organism Growth Cellular Senescence	Keratinization Intermediate Filament Organization
Pathways		Unwinding of DNA Unwinding of DNA	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) QT interval ( 19305408) TPE interval (resting) ( 32386560)	Cutaneous leishmaniasis ( 32830257) Diisocyanate-induced asthma ( 25918132) Telomere length ( 24465473)
Interacting Genes		9 interacting genes: CFTR CTNNA3 KRT80 MEOX2 MYO15B SETD6 SMARCD1 TRAPPC6A VAC14	23 interacting genes: AIRIM COPS3 GINS3 KRT14 KRT15 KRT16 KRT19 KRT20 KRT24 KRT25 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT38 KRT72 LCA5L LMO2 MEOX2 UCHL5
Entrez ID		64785	144501
HPRD ID		07842	14068
Ensembl ID		ENSG00000181938	ENSG00000167767
Uniprot IDs		A0A0S2Z5L0 A0A0S2Z5L4 A0A0S2Z5P2 Q9BRX5	Q6KB66
PDB IDs		2E9X 2EHO 2Q9Q 6XTX 6XTY 7PFO 7PLO 8B9D 8OK2
Enriched GO Terms of Interacting Partners?			Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Supramolecular Fiber Organization Epithelial Cell Differentiation Tissue Morphogenesis Cytoskeleton Organization Anatomical Structure Morphogenesis Cytoskeleton Organelle Organization Hair Cycle Structural Constituent Of Cytoskeleton Cell Differentiation Epidermis Development Extracellular Exosome Cellular Developmental Process Cytosol Developmental Process Tissue Development Hair Follicle Morphogenesis Intermediate Filament Cytoskeleton Cornified Envelope Keratinocyte Differentiation Protein Binding Keratinization Terminal Web Hair Cycle Process
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