CFAP68 and KLHL38

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CFAP68	KLHL38
Description		cilia and flagella associated protein 68	kelch like family member 38
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytoskeleton Cilium Axoneme Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath	Cytoplasm Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Flagellated Sperm Motility	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS			Atrial fibrillation ( 29892015) Carotid intima media thickness (mean) ( 31801372) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 25055868) Heel bone mineral density ( 30598549) PR interval ( 32439900) QRS duration ( 30012220) Systolic blood pressure ( 30578418)
Interacting Genes		35 interacting genes: AGXT ANKRD11 ARMC7 ATG9A ATPAF2 CATSPER1 CNOT2 COL8A1 DMRT3 DTX2 FOXH1 FRS3 HGS HOXA1 HOXC8 HR KANK2 KLHL38 KRTAP13-2 MGAT5B MYO15B OTX1 PATZ1 PEF1 PITX1 PLSCR4 PRKAB2 PROP1 PRR35 SETDB1 SMYD1 TEKT4 TLE5 TLX3 ZIC1	88 interacting genes: ADAMTSL4 ADRA2C AGR2 ASB12 BLZF1 CCDC33 CERCAM CFAP68 CFP CTAG1A CTAG1B CYSRT1 DMAC2L ECM1 FTO GOLGA6A GPRASP3 GSC2 HDHD3 IKZF3 KLHL20 KRT27 KRT31 KRT34 KRT35 KRT38 KRT39 KRT40 KRT85 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP13-1 KRTAP13-2 KRTAP2-3 KRTAP2-4 KRTAP3-3 KRTAP4-11 KRTAP5-9 KRTAP6-2 KRTAP9-2 KRTAP9-3 KRTAP9-8 LHX3 LHX4 MAGEA6 MDFI MEOX2 MGAT5B MKRN3 MORN3 NBPF19 NOTCH2NLA OIP5 PAX5 PBX4 PFDN5 PLSCR4 POF1B POU2AF1 RGS20 RSPO4 SLC15A2 SPRY4 TACC3 TADA2A TCF4 TEKT1 TEKT5 TENT5B TEPSIN TIMM10B TRAF1 TRIB3 TRIM42 TRIM54 TRIM69 TXNDC11 UBE3A USHBP1 WFDC5 WWOX YPEL3 ZNF341
Entrez ID		64776	340359
HPRD ID		12601	19276
Ensembl ID		ENSG00000137720	ENSG00000175946
Uniprot IDs		E9PS93 Q9H5F2	Q2WGJ6
PDB IDs		7UNG 8J07
Enriched GO Terms of Interacting Partners?		Sequence-specific Double-stranded DNA Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Anatomical Structure Morphogenesis Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Phospholipid Scramblase Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Corepressor Activity Plasma Membrane Phospholipid Scrambling Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Pattern Specification Process	Keratin Filament Intermediate Filament Structural Constituent Of Skin Epidermis Structural Molecule Activity Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Protein Binding Medial Motor Column Neuron Differentiation Epithelial Cell Differentiation Axonemal A Tubule Inner Sheath
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