PLPPR2 and GYPC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLPPR2	GYPC
Description		phospholipid phosphatase related 2	glycophorin C (Gerbich blood group)
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Plasma Membrane Membrane Cortical Cytoskeleton
	Molecular Function	Protein Binding Phosphatidate Phosphatase Activity	Protein Binding
	Biological Process	Phospholipid Metabolic Process Signal Transduction Phospholipid Dephosphorylation
Pathways		Lysosphingolipid and LPA receptors	Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS			Atrial fibrillation ( 29892015 30061737) Diastolic blood pressure ( 30224653) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Initial pursuit acceleration ( 29064472) Intelligence ( 22449649) Metabolite levels ( 23823483) Pelvic organ prolapse (moderate/severe) ( 26545240) Pyoderma gangrenosum in inflammatory bowel disease ( 24487271) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure ( 31217584) Tea consumption ( 31046077)
Interacting Genes		21 interacting genes: ARL13B CD79A CIAO2A CISD2 CLDN5 CREB3L1 GYPC KIR2DL3 LYPD5 MARCHF2 SCN3B SIGLEC12 SLC19A3 SMAGP SSMEM1 STX12 TMED9 TMEM237 TMIE UBE2J1 VSIR	13 interacting genes: ABHD16A AQP6 EPB41 GPR42 MPP1 PDIA3 PLPPR2 RHBDD1 SHISAL1 SLC10A6 TMEM14B TMEM88 TSPAN15
Entrez ID		64748	2995
HPRD ID		17442	00193
Ensembl ID		ENSG00000105520	ENSG00000136732
Uniprot IDs		A0A8I5KWF3 Q96GM1	P04921
PDB IDs			2EJY
Enriched GO Terms of Interacting Partners?		Membrane	PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Membrane Cortical Cytoskeleton Tapasin-ERp57 Complex Phosphatidylserine Catabolic Process Prostaglandin Catabolic Process Membrane Protein Proteolysis Involved In Retrograde Protein Transport, ER To Cytosol Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport
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