ATG3 and MOB2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATG3	MOB2
Description		autophagy related 3	MOB kinase activator 2
Image			No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Cytoplasm Cytosol Atg12-Atg5-Atg16 Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Transferase Activity Atg8-family Ligase Activity Atg12 Transferase Activity Ubiquitin-like Protein Transferase Activity Enzyme Binding Atg8-family Conjugating Enzyme Activity	Protein Binding Protein Kinase Activator Activity Metal Ion Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Protein Targeting To Membrane Autophagy Protein Transport Macroautophagy Protein Ubiquitination Mitochondrial Fragmentation Involved In Apoptotic Process Nucleophagy Negative Regulation Of Phagocytosis Glycophagy Regulation Of Cilium Assembly	Signal Transduction
Pathways		Macroautophagy
Drugs
Diseases
GWAS		Asthma (childhood onset) ( 23829686)	Brain morphology (MOSTest) ( 32665545) Myocardial infarction ( 33532862) Prostate cancer ( 29892016) Refractive error ( 32231278)
Interacting Genes		6 interacting genes: ATG12 ATG7 GABARAP GABARAPL2 MAP1LC3B MOB2	11 interacting genes: ATG3 CCDC90B FAAP20 FRA10AC1 MIIP NDRG2 NTAQ1 OR5H1 RETREG3 SFT2D2 STK38
Entrez ID		64422	81532
HPRD ID		10654	17581
Ensembl ID		ENSG00000144848	ENSG00000182208
Uniprot IDs		Q9NT62	Q70IA6
PDB IDs		4NAW 8AFI 8FKM
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Autophagy Of Mitochondrion Autophagosome Assembly Autophagosome Organization Macroautophagy Vacuole Organization Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagosome Autophagy Phosphatidylethanolamine Binding Protein-containing Complex Disassembly Cellular Response To Starvation Response To Starvation Organelle Assembly Cellular Response To Nutrient Levels Axoneme Phospholipid Binding Response To Nutrient Levels GABA Receptor Binding Piecemeal Microautophagy Of The Nucleus Microautophagy Nucleophagy Microtubule Binding Beta-tubulin Binding Catabolic Process Ubiquitin Protein Ligase Binding Regulation Of Protein Catabolic Process Cellular Component Assembly Atg8 Activating Enzyme Activity Atg12 Activating Enzyme Activity Organelle Organization Protein-containing Complex Organization Positive Regulation Of Viral Translation Cellular Response To Stress Cytosol Atg8-family Ligase Activity Positive Regulation Of Protein K48-linked Ubiquitination Cellular Response To Hyperoxia Atg12-Atg5-Atg16 Complex Regulation Of Protein K48-linked Ubiquitination Regulation Of Proteasomal Protein Catabolic Process Cytoplasmic Vesicle Positive Regulation Of Protein Catabolic Process Ceramide Binding Endomembrane System Ubiquitin-like Modifier Activating Enzyme Activity Glycophagy Protein Transport
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