RRAGC and NOL8

Number of citations of the paper that reports this interaction (PubMedID 14660641)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		RRAGC	NOL8
Description		Ras related GTP binding C	nucleolar protein 8
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Lysosome Lysosomal Membrane Cytosol Membrane Gtr1-Gtr2 GTPase Complex FNIP-folliculin RagC/D GAP	Nucleus Chromosome Nucleolus
	Molecular Function	Nucleotide Binding Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Protein-membrane Adaptor Activity Protein Heterodimerization Activity GTPase Binding Molecular Adaptor Activity Enzyme-substrate Adaptor Activity	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	Autophagosome Assembly Cytoplasmic Translation DNA-templated Transcription Apoptotic Process Lysosome Organization Small GTPase-mediated Signal Transduction Intracellular Protein Localization RNA Splicing Cellular Response To Starvation Negative Regulation Of Autophagy SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Destabilization Cellular Response To Nutrient Levels Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation TORC1 Signaling Response To Amino Acid Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus Protein Localization To Membrane Negative Regulation Of Protein Localization To Nucleus Regulation Of TORC1 Signaling Positive Regulation Of TORC1 Signaling	RRNA Processing Protein Localization To Nucleolus
Pathways		Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of PTEN gene transcription Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Beard thickness ( 26926045)	Malaria ( 31844061)
Interacting Genes		7 interacting genes: ATXN1L DEPDC5 MPP3 NOL8 RRAGA RRAGB WNT2	7 interacting genes: NIP7 RBFOX2 RNF10 RRAGA RRAGC RRAGD SNRNP40
Entrez ID		64121	55035
HPRD ID		12198	11397
Ensembl ID		ENSG00000116954	ENSG00000198000
Uniprot IDs		B4DQ03 B4DQG4 Q9HB90	A6H8Z4 Q76FK4
PDB IDs		3LLU 6CES 6EHR 6NZD 6S6A 6S6D 6SB0 6SB2 6U62 6ULG 6WJ2 6WJ3 7T3A 7T3B 7T3C 7UX2 7UXC 7UXH 8DHB
Enriched GO Terms of Interacting Partners?		Cellular Response To Amino Acid Starvation Response To Amino Acid Starvation Positive Regulation Of TORC1 Signaling GATOR1 Complex Gtr1-Gtr2 GTPase Complex Positive Regulation Of TOR Signaling Regulation Of TORC1 Signaling Regulation Of TOR Signaling Cellular Response To Starvation Response To Starvation Cellular Response To Nutrient Levels Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation Protein Localization To Lysosome TORC1 Signaling Lysosomal Membrane Regulation Of Autophagy Guanyl Ribonucleotide Binding Cellular Response To Amino Acid Stimulus TOR Signaling Protein Localization To Vacuole Response To Nutrient Levels Lysosome Regulation Of Translational Initiation Negative Regulation Of Autophagy Response To Amino Acid Cytoplasmic Translation Lung Induction Protein Localization To Organelle POZ Domain Binding Positive Regulation Of Translation Cell Proliferation In Midbrain Epithelial Cell Proliferation Involved In Lung Morphogenesis Regulation Of Branching Involved In Lung Morphogenesis Negative Regulation Of Translation Cellular Response To Methionine Atrial Cardiac Muscle Tissue Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Response To Methionine Intracellular Protein Localization Iris Morphogenesis FNIP-folliculin RagC/D GAP Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Positive Regulation Of Hematopoietic Stem Cell Proliferation Mammary Gland Epithelium Development Protein Localization To Nucleolus Wnt Signalosome Midbrain Dopaminergic Neuron Differentiation Cellular Response To Leucine Starvation GTPase Activity	Gtr1-Gtr2 GTPase Complex Cellular Response To Amino Acid Starvation Response To Amino Acid Starvation Positive Regulation Of TORC1 Signaling FNIP-folliculin RagC/D GAP Positive Regulation Of TOR Signaling Cellular Response To Amino Acid Stimulus Regulation Of TORC1 Signaling Negative Regulation Of Autophagy Response To Amino Acid Regulation Of TOR Signaling Cellular Response To Starvation Response To Starvation Protein-membrane Adaptor Activity Cellular Response To Nutrient Levels GTPase Binding Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation GTPase Activity Protein Localization To Lysosome Protein Heterodimerization Activity RNA Splicing GTP Binding TORC1 Signaling Lysosomal Membrane Regulation Of Autophagy Negative Regulation Of Catabolic Process GDP Binding TOR Signaling Protein Localization To Vacuole Autophagosome Assembly Response To Nutrient Levels Lysosome Autophagosome Organization Regulation Of Translational Initiation Nucleoplasm Nucleus Cytoplasmic Translation Positive Regulation Of Translation Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane GATOR1 Complex Vacuole Organization Organelle Assembly Negative Regulation Of Translation Cellular Response To Methionine Molecular Adaptor Activity Response To Methionine Sno(s)RNA-containing Ribonucleoprotein Complex Negative Regulation Of Schwann Cell Proliferation
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