SAMSN1 and SAP30

Number of citations of the paper that reports this interaction (PubMedID 20478393)
0

Data Source:
BioGRID (affinity chromatography technology, pull down)

		SAMSN1	SAP30
Description		SAM domain, SH3 domain and nuclear localization signals 1	Sin3A associated protein 30
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GO Annotations	Cellular Component	Ruffle Nucleus Cytoplasm Cytosol Cell Projection	Histone Deacetylase Complex Nucleus Nucleoplasm Sin3-type Complex
	Molecular Function	Phosphotyrosine Residue Binding RNA Binding	DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Adaptive Immune Response Negative Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of B Cell Activation Regulation Of Intracellular Signal Transduction	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Skeletal Muscle Cell Differentiation Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance
Pathways			HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS
Drugs
Diseases
GWAS		Coronary atherosclerosis (increased number of diseased vessels) (traffic exposure interaction) ( 28355232) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes		10 interacting genes: FASLG NEDD4 PILRB SAP30 SFN YWHAB YWHAE YWHAH YWHAQ YWHAZ	29 interacting genes: BRMS1 BRMS1L CIRSR CYTOR GABBR2 H2AC16 H2BC21 H3-4 H4C16 HBP1 HDAC1 HDAC2 HTT ID3 ING1 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A UHRF1 VHL YY1 ZNF395
Entrez ID		64092	8819
HPRD ID		06413	04540
Ensembl ID		ENSG00000155307	ENSG00000164105
Uniprot IDs		A0A2R8Y4K8 Q9NSI8 S6FRS6	O75446
PDB IDs		6UZJ	2KDP
Enriched GO Terms of Interacting Partners?		Phosphoserine Residue Binding Protein Domain Specific Binding Protein Sequestering Activity Transmembrane Transporter Binding Protein Targeting Regulation Of Nucleocytoplasmic Transport Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Establishment Of Protein Localization Phosphoprotein Binding Extracellular Exosome Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Substantia Nigra Development Negative Regulation Of RNA Metabolic Process Nuclear Receptor-mediated Corticosteroid Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transport Positive Regulation Of Nucleocytoplasmic Transport Neural Nucleus Development Negative Regulation Of Monoatomic Ion Transmembrane Transport Intracellular Protein Localization Regulation Of Intracellular Transport Cadherin Binding Negative Regulation Of Monoatomic Ion Transport Melanosome Signal Transduction Negative Regulation Of Transmembrane Transport Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Intracellular Transport Positive Regulation Of Protein Export From Nucleus Enzyme Binding Regulation Of Monoatomic Ion Transport Regulation Of Intracellular Protein Transport Negative Regulation Of Transport Focal Adhesion Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Localization Identical Protein Binding Intracellular Signal Transduction Regulation Of Protein Export From Nucleus Negative Regulation Of Metabolic Process Negative Regulation Of Protein Localization Regulation Of Macromolecule Metabolic Process	Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Population Maintenance Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Histone Deacetylase Binding Histone Deacetylase Complex Negative Regulation Of RNA Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Nucleoplasm Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Chromatin Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process NuRD Complex Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Metabolic Process Negative Regulation Of Cell Migration Regulation Of Cell Fate Specification Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Developmental Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Fate Commitment Transcription Corepressor Activity Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process ESC/E(Z) Complex Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Androgen Receptor Signaling Pathway Heterochromatin Formation Rhythmic Process Transcription Repressor Complex
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