PRDM14 and PATZ1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PRDM14	PATZ1
Description		PR/SET domain 14	POZ/BTB and AT hook containing zinc finger 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Male Germ Cell Nucleus Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA Binding RNA Binding Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Chromatin DNA Binding Metal Ion Binding Methyltransferase Regulator Activity Histone Methyltransferase Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Morphogenesis Cell Fate Specification Inner Cell Mass Cell Fate Commitment Regulation Of Transcription By RNA Polymerase II Germ Cell Development Embryo Implantation Fibroblast Growth Factor Receptor Signaling Pathway Fertilization Regulation Of Gene Expression Stem Cell Population Maintenance Germ-line Stem Cell Population Maintenance Methylation Epigenetic Regulation Of Gene Expression Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Gene Expression, Epigenetic Homeostasis Of Number Of Cells Within A Tissue Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Stem Cell Population Maintenance	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process Regulation Of DNA-templated Transcription Spermatogenesis Male Gonad Development Regulation Of Gene Expression Negative Regulation Of Endothelial Cell Migration T Cell Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription
Pathways		Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS		Schizophrenia ( 30285260) Testicular germ cell tumor ( 23666240 28604728 28604732)	Eosinophil percentage of white cells ( 32888494) Fish- and plant-related diet ( 32066663) Height ( 31562340) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Red cell distribution width ( 28957414) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494)
Interacting Genes		68 interacting genes: ABI2 AKAP9 AQP1 ATPAF2 BAG4 BAHD1 BCAR3 BEX2 CARD10 CASP8 CDCA7L CHEK2 CREB5 DGCR6 DMRT3 DRC4 EED EIF4E2 ENKD1 ERBB2 EZH2 FAM83A GEM GLYCTK GPATCH2L HEXIM2 HOXB5 HOXC8 HSP90AA2P HSPA5 HSPB7 ID3 IDH1 KANK2 LNX1 MIA3 MRPL32 MYPOP NDUFB9 PALB2 PATZ1 PAX2 PLEKHF2 PRKAB2 PRPF31 PSMA1 PTPRJ RAD51D RBM10 RCOR3 RUSC1 SAXO4 SCNM1 SNRPC SUZ12 TCAF1 TEAD4 TEKT4 TLE5 TRIM41 TSGA10 TTC32 TXK USP2 WDR25 ZNF250 ZNF587 ZNF835	82 interacting genes: ACTMAP AKAP8L BACH1 BACH2 BOLL BPIFA1 BRIP1 CEP76 CFAP68 CLK1 CPSF7 CYSRT1 DAZAP2 DVL3 EYA2 FAM168A FAM168B GOLGA6L9 GPANK1 HNRNPF HNRNPH1 HSPB2 HSPB2-C11orf52 HYI IQUB KLF1 KLHDC7B KRT33B KRTAP12-2 KRTAP13-2 KRTAP15-1 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 LMO2 LONRF1 LURAP1L LZTS2 MDFI MITF MSX2 NFKBID NHLRC4 OIP5 PFDN5 PHF1 PPP1R16B PPP1R37 PRDM14 PRDM6 PRKAR1A PRR20A PRR20B PRR20C PRR20D PRR20E PRR22 RBM10 RBPMS RBPMS2 RFX6 RIPPLY1 RNF4 SLAIN1 SMYD1 SPAG8 TLE5 TNS2 TRAF1 TRIP6 TSC1 WWOX WWP2 ZBTB32 ZIC1 ZIM2
Entrez ID		63978	23598
HPRD ID		11457	05522
Ensembl ID		ENSG00000147596	ENSG00000100105
Uniprot IDs		Q9GZV8	Q9HBE1
PDB IDs			2EPP 2EPQ 2EPR 2EPS 2YT9
Enriched GO Terms of Interacting Partners?		Chromatin Silencing Complex Protein Binding Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Ubiquitin Protein Ligase Binding Oligodendrocyte Differentiation ESC/E(Z) Complex Facultative Heterochromatin Formation Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Glial Cell Differentiation Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Identical Protein Binding Regulation Of Primary Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Anoikis Pronucleus Sex Chromatin Negative Regulation Of Transcription By RNA Polymerase II	Intermediate Filament Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Splicing
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