DMRTB1 and NXF1

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		DMRTB1	NXF1
Description		DMRT like family B with proline rich C-terminal 1	nuclear RNA export factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Transcription Export Complex Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule Nuclear Speck Nuclear RNA Export Factor Complex Nuclear Inclusion Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Metal Ion Binding	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Sex Differentiation	RNA Export From Nucleus MRNA Export From Nucleus Protein Transport Poly(A)+ MRNA Export From Nucleus MRNA Transport
Pathways			Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript
Drugs
Diseases
GWAS		Cerebrospinal fluid AB1-42 levels ( 28247064) Response to statin therapy ( 20339536)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		90 interacting genes: ALG13 ANKHD1 BAG4 BCAS2 C1orf94 CCND3 CDKN2D CPEB2 CPSF7 CTBP1 CTBP2 EWSR1 EXOSC1 EXOSC5 EXOSC7 EYA2 FXR2 HNRNPUL1 IL16 INCA1 KAT5 KIF21B KRT81 KRTAP19-5 KRTAP19-6 KRTAP21-2 KRTAP8-1 LARP4B LENG8 MAZ MBNL1 MRPL44 MSI2 MTPAP NCKIPSD NEDD9 NIF3L1 NIP7 NXF1 PARD6G PATL1 PEF1 PKP2 PPIL3 PRMT2 PRPF39 PRPF6 PRR3 PRRC2B QKI RAMAC RBFOX1 RBFOX2 RBM14 RBM22 RBM42 RBM7 RBPMS RPA2 RPS28 SECISBP2 SF1 SF3B4 SFPQ SH3RF1 SLAIN1 SLIRP SNRPA SNRPB SNRPC SNRPN SNW1 SORBS3 SRSF2 TENT5A TEX10 TLE5 TNRC6A TOX TRNAU1AP TSG101 TXNL4A UBL5 UNKL VASP WBP4 YTHDF1 YTHDF3 ZC3H10 ZMAT5	140 interacting genes: ALDOA ALYREF APOBEC3C AUNIP BACH2 BECN1 BICD2 BIN3 BIRC2 BLMH BTBD18 C10orf55 C1orf35 CAMK2G CCDC120 CCDC196 CCDC197 CCDC7 CDYL2 CEBPA CEP55 CLK2 CLK3 CPSF7 CSNK2A1 CTTN DDX50 DHX9 DMRTB1 DVL3 ECSIT EIF4A3 ELAVL4 ESRRA EXOSC8 FAM9A FTO GFAP GOLGA6L9 GPBP1 GTPBP2 HLA-DQA1 HNRNPUL1 HOMEZ HOXA1 HSF2BP IMPA1 IPO11 IPO4 ISY1-RAB43 KATNBL1 KCTD5 KCTD7 KIF24 KRT31 KRT40 LCE3E LDOC1 LUZP4 MAGOH MAP1A MAP1B MARK2 MBD3L1 MID2 MRNIP MTUS2 NKAPD1 NME1 NME4 NUP153 NUP214 NUP62 NUP98 NXF2 NXF3 NXF5 NXT1 NXT2 PEG10 PIH1D2 PPP1R12C PRKAR1B PRPH PRR3 PRRC2B PURB QKI RAD51 RAE1 RALYL RAN RANBP2 RBFOX2 RBM15B RBM22 RBMX RBPMS REDIC1 RPRD1A SGTA SH2D3A SH3GLB2 SLAIN1 SNRPA SNW1 SPATC1L SRPK2 SRSF1 SRSF3 SRSF4 SRSF7 SRSF8 STRAP SYCP3 TBC1D14 TCP10L TEX9 TFIP11 THOC5 TIFA TNFAIP1 TNPO1 TNPO2 TRA2A TRA2B U2AF1 UBQLN1 UBQLN4 UPF3A VAPA VIM VPS28 WEE2-AS1 XIST ZBED2 ZC3HAV1 ZNF250 ZNF343 ZNF438
Entrez ID		63948	10482
HPRD ID		16828	04035
Ensembl ID		ENSG00000143006	ENSG00000162231
Uniprot IDs		I6L9A0 Q96MA1	Q59E96 Q9UBU9
PDB IDs			1FO1 1FT8 1GO5 1JKG 1JN5 1KOH 1KOO 1OAI 2Z5K 2Z5M 3RW6 3RW7 4WYK 6E5U
Enriched GO Terms of Interacting Partners?		RNA Binding MRNA Processing RNA Processing MRNA Metabolic Process RNA Splicing Nucleic Acid Binding MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Nucleic Acid Metabolic Process Spliceosomal Complex Regulation Of MRNA Metabolic Process Nucleus MRNA Binding Nucleobase-containing Compound Metabolic Process Regulation Of RNA Splicing Nucleoplasm Cytoplasmic Stress Granule Regulation Of MRNA Splicing, Via Spliceosome Protein Binding Regulation Of MRNA Processing U1 SnRNP Macromolecule Metabolic Process U4/U6 X U5 Tri-snRNP Complex Catalytic Step 2 Spliceosome Negative Regulation Of Macromolecule Metabolic Process U2-type Prespliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Macromolecule Metabolic Process U5 SnRNP Spliceosomal Complex Assembly Negative Regulation Of Metabolic Process U2-type Precatalytic Spliceosome Negative Regulation Of RNA Metabolic Process Protein-RNA Complex Assembly Transcription Corepressor Activity Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Membraneless Organelle Assembly Nucleolar Exosome (RNase Complex) Negative Regulation Of MRNA Metabolic Process U2-type Catalytic Step 2 Spliceosome Intermediate Filament Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Ribonucleoprotein Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cytoplasm Regulation Of Metabolic Process Cytoplasmic Exosome (RNase Complex)	MRNA Transport RNA Transport Nucleobase-containing Compound Transport RNA Binding RNA Export From Nucleus MRNA Binding Nuclear Transport Nucleocytoplasmic Transport Nuclear Export Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing Regulation Of MRNA Processing MRNA Metabolic Process RNA Splicing MRNA Processing Regulation Of MRNA Metabolic Process MRNA Export From Nucleus Nucleic Acid Binding RNA Processing Nucleus Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Metabolic Process RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Intracellular Transport Nucleic Acid Metabolic Process Nuclear RNA Export Factor Complex Nucleoplasm Positive Regulation Of RNA Splicing Identical Protein Binding Import Into Nucleus Protein Binding Cellular Localization Nuclear Localization Sequence Binding Nuclear Pore Spliceosomal Complex Catalytic Step 2 Spliceosome Protein Import Into Nucleus Nucleobase-containing Compound Metabolic Process Nuclear Speck Positive Regulation Of MRNA Splicing, Via Spliceosome Establishment Of Localization In Cell Protein Localization To Nucleus Exon-exon Junction Complex Establishment Of Protein Localization To Organelle Poly(A)+ MRNA Export From Nucleus Protein Localization To Organelle Nuclear Envelope Intracellular Protein Transport Negative Regulation Of MRNA Metabolic Process
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