ANKEF1 and SSBP3

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		ANKEF1	SSBP3
Description		ankyrin repeat and EF-hand domain containing 1	single stranded DNA binding protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Transcription Regulator Complex Protein-containing Complex
	Molecular Function	Calcium Ion Binding Protein Binding	DNA Binding Single-stranded DNA Binding Transcription Coactivator Activity Protein Binding
	Biological Process		Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Cell Population Proliferation Prechordal Plate Formation Midbrain-hindbrain Boundary Initiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Mesendoderm Development Head Development Head Morphogenesis Protein-containing Complex Assembly Positive Regulation Of Anterior Head Development
Pathways
Drugs
Diseases
GWAS		Brain imaging measurements (variance) ( 32047264) Hip circumference ( 28552196)	Adult body size ( 32376654) Blood urea nitrogen levels ( 29403010 31152163) Body mass index ( 25673413) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits (multivariate) ( 32602732) Food allergy ( 25710614) Liver enzyme levels (alkaline phosphatase) ( 33972514) Menarche (age at onset) ( 27182965) Monocyte count ( 32888494) P wave duration ( 28794112) Platelet distribution width ( 32888494 27863252) PR interval ( 32439900) Refractive error ( 32231278) Serum bilirubin levels in metabolic syndrome ( 30621171) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149) TPE interval (resting) ( 32386560) Triglyceride levels ( 32203549 32154731)
Interacting Genes		6 interacting genes: AAR2 JMJD6 KDM1A KIZ SSBP3 VHL	20 interacting genes: ANKEF1 APP ARNT2 BLK CLK1 DTNB EWSR1 HCLS1 IL36RN LDB1 LDB2 NXT2 PIN1 RFC1 SIVA1 SS18L1 SUPT5H TBC1D23 YES1 ZNF226
Entrez ID		63926	23648
HPRD ID		10652	09578
Ensembl ID		ENSG00000132623	ENSG00000157216
Uniprot IDs		Q9NU02	Q9BWW4 Q9NW25
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Demethylase Activity Histone Demethylase Activity Histone H4R3 Demethylase Activity Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Peptidyl-lysine 5-dioxygenase Activity Histone H3R2 Demethylase Activity Oxidative RNA Demethylation Prechordal Plate Formation Midbrain-hindbrain Boundary Initiation Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Positive Regulation Of Anterior Head Development Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Negative Regulation Of Protein Homooligomerization Oxidative RNA Demethylase Activity P-TEFb Complex Binding Negative Regulation Of Protein Oligomerization DNA-binding Transcription Factor Binding Positive Regulation Of RNA Metabolic Process MRF Binding Response To Fungicide Guanine Metabolic Process Recognition Of Apoptotic Cell Transcription Elongation Factor Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Histone H3K4 Demethylase Activity Oxidative Demethylation Peptidyl-lysine Hydroxylation Mesendoderm Development Formation Of Anatomical Boundary Transcription Regulator Complex Histone H3K9 Demethylase Activity Head Morphogenesis Demethylation Transcription Regulator Activator Activity Transcription Coactivator Activity Positive Regulation Of Cell Size Phagocytosis, Recognition Regulation Of Transcription By RNA Polymerase II DNA Repair Complex Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Protein Hydroxylation Positive Regulation Of Biosynthetic Process Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Transcription By RNA Polymerase II RNA Splicing	Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Non-membrane Spanning Protein Tyrosine Kinase Activity Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process LIM Domain Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Enzyme Binding Negative Regulation Of Transcription By RNA Polymerase II Antifungal Humoral Response Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Transcription Regulator Complex Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Protein Tyrosine Kinase Activity Transcription Coregulator Activity Regulation Of Macromolecule Metabolic Process Nucleus Regulation Of Primary Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of Protein Localization To Nucleus Epithelial Structure Maintenance Positive Regulation Of Macromolecule Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Dendrite Development Cis-trans Isomerase Activity Hair Follicle Development CD27 Receptor Binding Regulation Of Metabolic Process Regulation Of Amyloid Precursor Protein Catabolic Process Defense Response To Fungus Acetylcholine Receptor Activator Activity Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Response To Fungus Lipoprotein Particle
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