CXCL5 and XCL2

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down)

		CXCL5	XCL2
Description		C-X-C motif chemokine ligand 5	X-C motif chemokine ligand 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity Identical Protein Binding CXCR Chemokine Receptor Binding	Cytokine Activity Protein Binding Chemokine Activity CCR Chemokine Receptor Binding
	Biological Process	Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Neutrophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide	Chemotaxis Inflammatory Response Immune Response Signal Transduction Blood Circulation Positive Regulation Of Cell Migration Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (q) signalling events
Drugs
Diseases
GWAS		CXCL5 levels ( 25147954) Inflammatory bowel disease ( 23128233) Metabolite levels ( 22916037) Urate levels (BMI interaction) ( 25811787)	Emphysema imaging phenotypes ( 26030696) Lung cancer ( 28604730) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		20 interacting genes: ACKR1 ACTN3 ALPP CCL11 CCL20 CXCL1 CXCL14 CXCL2 CXCL3 CXCR1 CXCR2 EFEMP2 FBLN1 GRN MEOX2 MGAT5B MMP9 NOTCH2NLA VWC2L XCL2	19 interacting genes: CCL2 CCL20 CCL21 CCL26 CCL28 CCL5 CCL7 CCL8 CXCL12 CXCL17 CXCL2 CXCL3 CXCL5 KRTAP1-3 KRTAP10-9 NOTCH2NLA PF4 PF4V1 XCR1
Entrez ID		6374	6846
HPRD ID		08976	05317
Ensembl ID		ENSG00000163735	ENSG00000143185
Uniprot IDs		P42830 Q6I9S7	Q9UBD3
PDB IDs		2MGS 8XWS 8XX7
Enriched GO Terms of Interacting Partners?		Chemokine Activity Cell Chemotaxis Cytokine Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemotaxis Locomotion Antimicrobial Humoral Response Killing Of Cells Of Another Organism Humoral Immune Response Cell Migration Chemokine-mediated Signaling Pathway Extracellular Region Cell Killing Cell Motility Inflammatory Response Extracellular Space Interleukin-8-mediated Signaling Pathway Interleukin-8 Receptor Activity Granulocyte Chemotaxis C-C Chemokine Binding Immune Response Granulocyte Migration Interleukin-8 Binding Leukocyte Migration Defense Response Elastic Fiber Defense Response To Symbiont Myeloid Leukocyte Migration Immune System Process Defense Response To Other Organism Embryo Implantation Leukocyte Chemotaxis Signal Transduction Positive Regulation Of Cell Migration Neutrophil Chemotaxis C-X-C Chemokine Receptor Activity Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Neutrophil Migration Response To External Biotic Stimulus Regulation Of Cell Migration Cytokine-mediated Signaling Pathway Regulation Of Cell Motility Regulation Of Locomotion Response To Other Organism Dendritic Cell Chemotaxis G Protein-coupled Receptor Signaling Pathway Mononuclear Cell Migration Chemokine Receptor Activity C-C Chemokine Receptor Activity	Chemokine Activity Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemotaxis Antimicrobial Humoral Response Locomotion Leukocyte Chemotaxis Cytokine Activity Leukocyte Migration Humoral Immune Response Granulocyte Chemotaxis Myeloid Leukocyte Migration Granulocyte Migration Cell Migration Inflammatory Response Cell Motility Defense Response To Symbiont Defense Response To Other Organism Mononuclear Cell Migration Immune Response Chemokine-mediated Signaling Pathway Eosinophil Chemotaxis Eosinophil Migration Defense Response Response To Other Organism CCR Chemokine Receptor Binding Immune System Process Extracellular Space Killing Of Cells Of Another Organism Regulation Of Leukocyte Migration CXCR Chemokine Receptor Binding Extracellular Region Response To External Biotic Stimulus Positive Regulation Of Leukocyte Migration Positive Regulation Of Mononuclear Cell Migration Cell Killing Monocyte Chemotaxis Regulation Of Lymphocyte Migration Positive Regulation Of Chemotaxis Regulation Of Mononuclear Cell Migration Cytokine-mediated Signaling Pathway Chemokine Receptor Binding Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Lymphocyte Migration Regulation Of Chemotaxis Positive Regulation Of Cell Migration Neutrophil Chemotaxis Positive Regulation Of Cell Motility Negative Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Locomotion
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