CCL16 and SDF2

		CCL16	SDF2
Description		C-C motif chemokine ligand 16	stromal cell derived factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Endoplasmic Reticulum Protein Folding Chaperone Complex
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity Chemoattractant Activity CCR Chemokine Receptor Binding	Misfolded Protein Binding
	Biological Process	Chemotaxis Inflammatory Response Immune Response Cell Communication Cell-cell Signaling Positive Regulation Of Cell Migration Eosinophil Chemotaxis Positive Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway	Protein Refolding
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs			Malonate Ion
Diseases
GWAS		Initial pursuit acceleration ( 29064472)
Interacting Genes		9 interacting genes: CCL5 CCR1 CCR5 CCR8 HRH4 MX1 SDF2 SMG6 UBQLN2	7 interacting genes: CCL15 CCL16 CCL8 HNRNPD HSPB2 UBC ZNF18
Entrez ID		6360	6388
HPRD ID		03233	04243
Ensembl ID		ENSG00000275152	ENSG00000132581
Uniprot IDs		O15467	Q6IBU4 Q99470
PDB IDs		5LTL 7SCT 8FK9
Enriched GO Terms of Interacting Partners?		Chemokine Receptor Activity Chemokine-mediated Signaling Pathway Dendritic Cell Migration Dendritic Cell Chemotaxis C-C Chemokine Binding C-C Chemokine Receptor Activity Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity Chemokine (C-C Motif) Ligand 5 Binding Positive Regulation Of Cytosolic Calcium Ion Concentration Cytokine-mediated Signaling Pathway Cell Chemotaxis Response To Cytokine Response To Peptide Negative Regulation Of Macrophage Apoptotic Process Chemotaxis Mononuclear Cell Migration G Protein-coupled Receptor Signaling Pathway Locomotion G Protein-coupled Receptor Activity Cellular Response To Cytokine Stimulus Leukocyte Chemotaxis Positive Regulation Of Neuroinflammatory Response Negative Regulation Of Myeloid Cell Apoptotic Process Positive Regulation Of Monocyte Chemotaxis Monocyte Chemotaxis Calcium-mediated Signaling Inflammatory Response Regulation Of Monocyte Chemotaxis Regulation Of Myeloid Cell Apoptotic Process Immune Response Cell-cell Signaling Leukocyte Migration Regulation Of Neuroinflammatory Response Signaling Calcium Ion Transport Cell Communication Negative Regulation Of Viral Genome Replication Defense Response G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Negative Regulation Of Leukocyte Apoptotic Process Coreceptor Activity Chemokine Receptor Antagonist Activity Chemokine (C-C Motif) Ligand 5 Signaling Pathway CCR4 Chemokine Receptor Binding Intracellular Signaling Cassette External Side Of Plasma Membrane Negative Regulation Of Viral Process Regulation Of Viral Genome Replication Cell Migration Chemokine (C-C Motif) Ligand 7 Binding	CCR Chemokine Receptor Binding Chemokine Activity Chemokine-mediated Signaling Pathway Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Eosinophil Migration Eosinophil Chemotaxis Cell Chemotaxis Cytokine Activity Chemoattractant Activity Humoral Immune Response Positive Chemotaxis Chemotaxis Locomotion Hepatocyte Dedifferentiation Cellular Response To Putrescine Granulocyte Chemotaxis Cytokine-mediated Signaling Pathway Granulocyte Migration Circadian Regulation Of Translation Inflammatory Response Positive Regulation Of Cell Migration Myeloid Leukocyte Migration Positive Regulation Of Cell Motility Leukocyte Chemotaxis Positive Regulation Of Locomotion Cell-cell Signaling Signaling Extracellular Space Somatic Muscle Development Cell Communication Heparin Binding Positive Regulation Of Telomere Capping MCRD-mediated MRNA Stability Complex Response To Rapamycin Cell Dedifferentiation Intracellular Calcium Ion Homeostasis Defense Response To Symbiont Defense Response To Other Organism G Protein-coupled Receptor Signaling Pathway Calcium Ion Homeostasis Response To Sodium Phosphate Minor Groove Of Adenine-thymine-rich DNA Binding Leukocyte Migration Cell Migration CRD-mediated MRNA Stabilization Phospholipase Activator Activity Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Host-mediated Suppression Of Viral Genome Replication Regulation Of Cell Migration
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