CCL13 and CXCL17

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down)

		CCL13	CXCL17
Description		C-C motif chemokine ligand 13	C-X-C motif chemokine ligand 17
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Signaling Receptor Binding Cytokine Activity Protein Binding Chemokine Activity CCR Chemokine Receptor Binding	Protein Binding
	Biological Process	Intracellular Calcium Ion Homeostasis Chemotaxis Inflammatory Response Immune Response Cytoskeleton Organization Signal Transduction Cell-cell Signaling Regulation Of Cell Shape Positive Regulation Of Cell Migration Killing Of Cells Of Another Organism Eosinophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway	Angiogenesis Chemotaxis Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Macrophage Chemotaxis Cell Differentiation Macrophage Chemotaxis Negative Regulation Of Inflammatory Response Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Monocyte Chemotaxis
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Crohn's disease ( 22412388) Inflammatory bowel disease ( 23128233) Metabolite levels ( 23823483)
Interacting Genes		28 interacting genes: ACKR2 ACKR4 APAF1 APP CCL11 CCL2 CCL21 CCL24 CCL26 CCL28 CCL5 CCL8 CCR1 CCR3 CCR5 CXCL10 CXCL11 CXCL12 CXCL14 CXCL17 CXCL9 HNRNPH3 MMP1 MMP3 NOD2 PF4 PPBP XCL1	16 interacting genes: CCL13 CCL2 CCL20 CCL21 CCL25 CCL26 CCL28 CCL5 CCL8 CXCL10 CXCL12 CXCL14 CXCL9 PF4 XCL1 XCL2
Entrez ID		6357	284340
HPRD ID		03230	18264
Ensembl ID		ENSG00000181374	ENSG00000189377
Uniprot IDs		Q99616	Q6UXB2
PDB IDs		2RA4
Enriched GO Terms of Interacting Partners?		Cell Chemotaxis Chemotaxis Chemokine Activity Locomotion Chemokine-mediated Signaling Pathway Leukocyte Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Leukocyte Migration Myeloid Leukocyte Migration Humoral Immune Response Immune Response Granulocyte Chemotaxis Cytokine Activity Cell Migration Granulocyte Migration Cytokine-mediated Signaling Pathway Cell Motility Immune System Process Defense Response Inflammatory Response Defense Response To Symbiont Mononuclear Cell Migration Defense Response To Other Organism G Protein-coupled Receptor Signaling Pathway Killing Of Cells Of Another Organism CCR Chemokine Receptor Binding Cell Killing Response To External Biotic Stimulus Response To Other Organism Positive Regulation Of Leukocyte Migration Regulation Of Leukocyte Migration Eosinophil Chemotaxis Eosinophil Migration Positive Regulation Of Chemotaxis Extracellular Space Response To Stress CXCR Chemokine Receptor Binding Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Mononuclear Cell Migration Extracellular Region Regulation Of Chemotaxis Positive Regulation Of Cell Migration Regulation Of Mononuclear Cell Migration Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Cell Motility Chemokine Receptor Binding Positive Regulation Of Locomotion Cell-cell Signaling Positive Regulation Of Calcium Ion Transport	Chemokine Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Cell Chemotaxis Cytokine Activity Humoral Immune Response Chemotaxis Locomotion Granulocyte Chemotaxis Chemokine-mediated Signaling Pathway Leukocyte Chemotaxis Granulocyte Migration Leukocyte Migration Killing Of Cells Of Another Organism Myeloid Leukocyte Migration Defense Response To Symbiont CCR Chemokine Receptor Binding Defense Response To Other Organism Cell Migration Cell Killing Cell Motility Response To Other Organism Inflammatory Response Immune Response Cytokine-mediated Signaling Pathway Response To External Biotic Stimulus Defense Response Extracellular Space Eosinophil Chemotaxis Eosinophil Migration Chemokine Receptor Binding Mononuclear Cell Migration Immune System Process Regulation Of Leukocyte Migration G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Migration Extracellular Region Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Lymphocyte Migration Positive Regulation Of Leukocyte Migration Positive Regulation Of T Cell Migration CXCR Chemokine Receptor Binding Negative Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Lymphocyte Migration Response To Stress Positive Regulation Of Mononuclear Cell Migration
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