CCL7 and FEZ1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CCL7	FEZ1
Description		C-C motif chemokine ligand 7	fasciculation and elongation protein zeta 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Cytoplasm Golgi Apparatus Centrosome Cytoskeleton Microtubule Plasma Membrane Membrane Axon Dendrite Growth Cone Cell Projection Neuronal Cell Body
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity Heparin Binding CCR1 Chemokine Receptor Binding CCR2 Chemokine Receptor Binding CCR Chemokine Receptor Binding	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding
	Biological Process	Monocyte Chemotaxis Intracellular Calcium Ion Homeostasis Chemotaxis Inflammatory Response Immune Response Cytoskeleton Organization Signal Transduction Canonical NF-kappaB Signal Transduction Cell-cell Signaling Regulation Of Cell Shape Response To Gamma Radiation Signal Transduction Involved In Regulation Of Gene Expression Positive Regulation Of Cell Migration Eosinophil Chemotaxis Positive Regulation Of Inflammatory Response Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Ethanol Negative Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Natural Killer Cell Chemotaxis	Mitochondrion Organization Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Hippocampus Development Establishment Of Cell Polarity Establishment Of Mitochondrion Localization Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Cellular Response To Growth Factor Stimulus Negative Regulation Of Autophagosome Assembly
Pathways		Chemokine receptors bind chemokines
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Crohn's disease ( 21102463 22412388 28067908) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 28067908)	Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874) Breast cancer (survival) ( 25890600) Schizophrenia ( 22688191 23894747)
Interacting Genes		20 interacting genes: AATF ACKR1 ACKR2 ACKR4 CCR1 CCR10 CCR3 CCR5 CXCL6 ERBB2 FEZ1 MMP1 MMP13 MMP14 MMP2 MMP3 TLE5 UBQLN1 UBQLN2 XCL2	60 interacting genes: BARD1 BORA BRD1 C8orf33 CCL7 CEP126 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 DYRK1A FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT LRIF1 MEST NBR1 NDUFB9 NEK1 NRIP1 OLFML3 P4HB PAM16 PCNT PDCD7 PPP4R3B PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 STAR TAC3 TAF1D TAF9 TBC1D25 TEDC2 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251
Entrez ID		6354	9638
HPRD ID		01150	09212
Ensembl ID		ENSG00000108688	ENSG00000149557
Uniprot IDs		P80098	Q99689
PDB IDs		1BO0 1NCV 4ZKC 7S58 7S59 7SCU 8FJ3 8FK6 8FK8 8JPS
Enriched GO Terms of Interacting Partners?		Chemokine-mediated Signaling Pathway C-C Chemokine Binding Chemokine Receptor Activity C-C Chemokine Receptor Activity Cell Chemotaxis Chemotaxis Locomotion Cytokine-mediated Signaling Pathway Collagen Catabolic Process Extracellular Matrix Disassembly Collagen Metabolic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Migration Cell Surface Receptor Signaling Pathway Calcium-mediated Signaling Endopeptidase Activity Metalloendopeptidase Activity Cell Motility G Protein-coupled Receptor Signaling Pathway Cellular Response To UV-A G Protein-coupled Receptor Activity Metallopeptidase Activity Response To UV-A Serine-type Endopeptidase Activity Chemokine (C-C Motif) Ligand 5 Binding Inflammatory Response Immune System Process External Side Of Plasma Membrane Immune Response Response To Stress Extracellular Structure Organization Extracellular Matrix Organization Leukocyte Chemotaxis Chemokine Binding Intracellular Signaling Cassette Response To Amyloid-beta Defense Response Extracellular Matrix Leukocyte Migration Peptidase Activity Cellular Response To UV Signal Transduction Dendritic Cell Chemotaxis Positive Regulation Of ERAD Pathway Mononuclear Cell Migration Proteolysis Cellular Response To Light Stimulus Plasma Membrane Response To Cytokine Dendritic Cell Migration	Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Autophagosome Microtubule Cytoskeleton Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Regulation Of Cellular Response To Stress Centrosome Regulation Of Macroautophagy Microtubule Cytoskeleton Organization Involved In Mitosis Microtubule-based Process Positive Regulation Of Protein Lipidation Cytoskeleton Regulation Of Endoplasmic Reticulum Tubular Network Organization RNA Polymerase II General Transcription Initiation Factor Binding Regulation Of Protein Lipidation Regulation Of Organelle Assembly Regulation Of Microtubule-based Process RNA Polymerase II General Transcription Initiation Factor Activity Positive Regulation Of Macroautophagy Positive Regulation Of Organelle Assembly Regulation Of Autophagy Microtubule Organizing Center Mitotic Spindle Organization Axon Negative Regulation Of Microtubule Polymerization Or Depolymerization Chondroitin Sulfate Binding Regulation Of Autophagosome Assembly Regulation Of Organelle Organization
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