MSMO1 and TMEM242

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MSMO1	TMEM242
Description		methylsterol monooxygenase 1	transmembrane protein 242
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	C-4 Methylsterol Oxidase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity	Protein Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Steroid Biosynthetic Process Cholesterol Biosynthetic Process Steroid Metabolic Process Cholesterol Metabolic Process Lipid Biosynthetic Process Sterol Biosynthetic Process	Mitochondrial Proton-transporting ATP Synthase Complex Assembly
Pathways		Cholesterol biosynthesis Cholesterol biosynthesis via lathosterol
Drugs		NADH
Diseases
GWAS		Heel bone mineral density ( 30598549) Neuroticism ( 27067015)	Ankle-brachial index ( 31388106) General risk tolerance (MTAG) ( 30643258) Lipoprotein (a) levels ( 26377243)
Interacting Genes		19 interacting genes: ATXN1 CHRM5 CYP4F22 DNAJC30 ERG28 GOLT1A GPR35 HMOX1 MARCHF6 MMP14 STRIT1 STX3 TMEM11 TMEM140 TMEM242 TMEM65 TMEM86B VKORC1 YIF1A	36 interacting genes: AQP6 ATP6V0B BCL2L13 CNR2 CYB561 EBP ELOVL4 GGT7 GHITM GJA8 GOLT1A GPR42 GRINA HSD17B11 IL10RA JAGN1 MFSD2A MFSD6 MSMO1 MTIF3 NDUFA3 PLP1 RNF5 SGPL1 SLC10A1 SLC10A6 SLC19A3 SLC29A2 SLC30A3 SYNJ2BP TMBIM1 TMEM179B TMEM31 TMEM51 TMIE VKORC1
Entrez ID		6307	729515
HPRD ID		07396
Ensembl ID		ENSG00000052802	ENSG00000215712
Uniprot IDs		Q15800	Q9NWH2
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane	Membrane Transmembrane Transport Endoplasmic Reticulum Bile Acid:sodium Symporter Activity Monoatomic Ion Transport Lipid Biosynthetic Process Monoatomic Cation Transport Inorganic Cation Transmembrane Transport Endoplasmic Reticulum Membrane Small Molecule Biosynthetic Process Pyrimidine-containing Compound Transmembrane Transport Inorganic Ion Transmembrane Transport Monoatomic Ion Transmembrane Transport Calcium Channel Activity Steroid Biosynthetic Process Bile Acid And Bile Salt Transport
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