SAFB and SAFB2

Number of citations of the paper that reports this interaction (PubMedID 12660241)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		SAFB	SAFB2
Description		scaffold attachment factor B	scaffold attachment factor B2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Midbody	Nucleus Nucleoplasm Cytoplasm Nuclear Body Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Nucleic Acid Binding DNA Binding Chromatin Binding Double-stranded DNA Binding RNA Binding Protein Binding Sequence-specific DNA Binding	Nucleic Acid Binding DNA Binding RNA Binding Protein Binding Identical Protein Binding Sequence-specific DNA Binding
	Biological Process	Chromatin Organization Regulation Of Transcription By RNA Polymerase II Estrogen Receptor Signaling Pathway Regulation Of MRNA Processing Regulation Of Androgen Receptor Signaling Pathway	Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Processing Sertoli Cell Differentiation Regulation Of Androgen Receptor Signaling Pathway
Pathways		SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494)	Creativity ( 32133506) Obsessive-compulsive symptoms ( 26859814) vWF and FVIII levels ( 21810271)
Interacting Genes		31 interacting genes: ABHD16A CDC37 CEBPA CHD1 CHD3 CLK1 CSNK2A1 CYCS ESR1 HNRNPA1 HNRNPD HNRNPK IL7R LINC00941 MIR199A1 MIR363 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7D NCOR1 POLR2A RFX2 SAFB2 SREK1 SRPK1 SRPK2 SRSF9 SUMO2 TAF15 TJP2	14 interacting genes: CEBPA CHGB ERBB2 ESR1 FNTA FUS FXR1 GIT2 RNF10 SAFB SIRPA SORBS3 SUMO2 ZSCAN18
Entrez ID		6294	9667
HPRD ID		04205	06424
Ensembl ID		ENSG00000160633	ENSG00000130254
Uniprot IDs		B7Z2F6 B7ZLP5 Q15424	Q14151
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of MRNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulatory NcRNA-mediated Gene Silencing Regulation Of Metabolic Process Regulation Of RNA Splicing MiRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Regulation Of Gene Expression Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Regulation Of MRNA Processing Post-transcriptional Gene Silencing Regulation Of Primary Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process RISC Complex Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression RNA Splicing MRNA Base-pairing Post-transcriptional Repressor Activity Nucleoplasm Negative Regulation Of Metabolic Process Nucleic Acid Binding RNA Binding MRNA Metabolic Process Chromatin RNA Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of MRNA Metabolic Process Negative Regulation Of Interleukin-6-mediated Signaling Pathway Protein Domain Specific Binding Positive Regulation Of Catabolic Process MRNA 3'-UTR Binding Chromatin Organization Positive Regulation Of Nucleobase-containing Compound Metabolic Process RNA Processing MRNA Processing DNA Binding Positive Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of MRNA Stability Nucleus Nucleic Acid Metabolic Process ATP-dependent Chromatin Remodeler Activity	Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Positive Regulation Of Rho Protein Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Intracellular Signal Transduction Positive Regulation Of Small GTPase Mediated Signal Transduction Estrogen Receptor Signaling Pathway Presynaptic Cytosol Postsynaptic Cytosol Regulation Of Inflammatory Response Neuromuscular Junction Development Chromatin Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Molecular Condensate Scaffold Activity RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Peptide Pheromone Maturation Presynapse Glutamatergic Synapse Regulation Of Primary Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Cell Development Regulation Of Metabolic Process Regulation Of Signal Transduction Receptor Tyrosine Kinase Binding Regulation Of Nitric Oxide Metabolic Process Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Response To Vitamin B2 C/EBP Complex ERBB3:ERBB2 Complex Protein-containing Complex Localization CAAX-protein Geranylgeranyltransferase Activity CAAX-protein Geranylgeranyltransferase Complex Protein Farnesyltransferase Activity Protein Farnesyltransferase Complex Cellular Response To Interleukin-12 Negative Regulation Of Multicellular Organismal Process Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Negative Regulation Of MRNA Catabolic Process Positive Regulation Of Metabolic Process
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