MRPL12 and NTM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MRPL12	NTM
Description		mitochondrial ribosomal protein L12	neurotrimin
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Large Ribosomal Subunit Ribosome Ribonucleoprotein Complex	Extracellular Region Plasma Membrane Membrane Side Of Membrane
	Molecular Function	RNA Binding MRNA Binding Structural Constituent Of Ribosome Protein Binding	Protein Binding
	Biological Process	Mitochondrial Transcription Translation Mitochondrial Translation Positive Regulation Of DNA-templated Transcription	Cell Adhesion Neuron Recognition
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial protein degradation Mitochondrial ribosome-associated quality control	Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Refractive error ( 32231278) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)	Adult body size ( 32376654) Aggressiveness in attention deficit hyperactivity disorder ( 27021288) Alzheimer's disease ( 33654092) Asperger disorder ( 21182207) Blood protein levels ( 30072576) Body size at age 10 ( 32376654) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Familial lung adenocarcinoma ( 29924316) Feeling worry ( 29500382) Femur bone mineral density x serum urate levels interaction ( 34046847) Food addiction ( 27106561) Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Glucocorticoid-induced osteonecrosis (time dependent analysis) ( 26265699) Gut microbiota (functional units) ( 27694959) Intake of total sugars ( 31005972) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Male fertility ( 22633400) Mental health study participation (completed survey) ( 31263887) Myopia ( 27182965) Obesity-related traits ( 23251661) Plasma anti-thyroglobulin levels ( 29678681) Pre-treatment viral load in HIV-1 infection ( 31219150) Refractive error ( 32231278) Serum polyunsaturated fatty acid concentration x sex interaction in metabolic syndrome ( 31991592) Severe exacerbations in childhood asthma ( 33093117) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Sunburns ( 23548203)
Interacting Genes		26 interacting genes: CBX3 COX6A2 DRC8 EFEMP2 EXOC3L2 FBLN1 KRTAP10-1 MAPRE3 MICOS10-NBL1 MORF4L1 MORF4L2 NBL1 NTAQ1 NTM OLIG1 POLR1D PPP1R16A RARG SAT1 SEPTIN1 SMG6 TMEM51 TRIM59 TXNDC9 UBC ZNF76	20 interacting genes: APP C19orf47 CCKBR EFEMP2 KRTAP1-1 KRTAP3-2 KRTAP5-9 KRTAP9-3 LHB LINGO1 LSAMP MRPL12 NBPF19 NEGR1 NOTCH2NLA P4HB PAX4 QRFPR SPRY1 VWC2
Entrez ID		6182	50863
HPRD ID		03849	06398
Ensembl ID		ENSG00000262814	ENSG00000182667
Uniprot IDs		P52815	B7Z1I4 B7Z1Z5 Q9P121
PDB IDs		6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7L08 7L20 7O9K 7O9M 7OG4 7PO2 7PO4 7QI4 7QI5 7QI6 8ANY 8OIR 8OIT	6DLF
Enriched GO Terms of Interacting Partners?		Elastic Fiber Determination Of Dorsal Identity Sequestering Of BMP In Extracellular Matrix Sequestering Of BMP From Receptor Via BMP Binding Morphogen Activity Negative Regulation Of Monocyte Chemotaxis Sequestering Of Extracellular Ligand From Receptor Extracellular Negative Regulation Of Signal Transduction BMP Binding Negative Regulation Of Leukocyte Chemotaxis Negative Regulation Of Stem Cell Proliferation NuA4 Histone Acetyltransferase Complex	Intermediate Filament
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