RPLP2 and TIMM10B

		RPLP2	TIMM10B
Description		ribosomal protein lateral stalk subunit P2	translocase of inner mitochondrial membrane 10B
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Ribosome Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Extracellular Exosome Ribonucleoprotein Complex	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Membrane Mitochondrial Intermembrane Space Chaperone Complex TIM22 Mitochondrial Import Inner Membrane Insertion Complex
	Molecular Function	Structural Constituent Of Ribosome Protein Binding	Protein Binding Metal Ion Binding Unfolded Protein Binding Protein Transporter Activity
	Biological Process	Cytoplasmic Translation Cytoplasmic Translational Elongation Translation Translational Elongation	Cell-matrix Adhesion Protein Transport Protein Insertion Into Mitochondrial Inner Membrane
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	Mitochondrial protein import
Drugs
Diseases
GWAS		Intraocular pressure ( 29785010) Keratoconus ( 33649486)	Malaria ( 31844061)
Interacting Genes		9 interacting genes: GRK2 LINC00839 MAPK8 PTEN RPLP1 SRPK2 TIMM10B WEE2-AS1 YWHAQ	8 interacting genes: EIF3F HGS KLHL38 LDHC MBD3 MEIS2 PLD2 RPLP2
Entrez ID		6181	26515
HPRD ID		01612	16242
Ensembl ID		ENSG00000177600	ENSG00000132286
Uniprot IDs		P05387	B2R4A9 Q9Y5J6
PDB IDs		1S4J 2JDL 2LBF 2W1O 4BEH 4V6X 5DDZ 5GU4	7CGP
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Relaxation Of Smooth Muscle Edg-2 Lysophosphatidic Acid Receptor Binding Protein Serine/threonine Kinase Activity Synapse Negative Regulation Of The Force Of Heart Contraction By Chemical Signal Peptidyl-serine Phosphorylation Intracellular Signaling Cassette JUN Phosphorylation Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity 14-3-3 Protein Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?