ZFAND3 and MTCH1

		ZFAND3	MTCH1
Description		zinc finger AN1-type containing 3	mitochondrial carrier 1
Image			No pdb structure
GO Annotations	Cellular Component		Mitochondrion Mitochondrial Outer Membrane Membrane
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Membrane Insertase Activity
	Biological Process		Apoptotic Process Regulation Of Signal Transduction Positive Regulation Of Apoptotic Process Protein Insertion Into Mitochondrial Outer Membrane Neuronal Ion Channel Clustering
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Daytime nap ( 33568662) Insulin resistance/response ( 21901158) Post bronchodilator FEV1/FVC ratio ( 26634245) Serum alkaline phosphatase levels ( 33339817) Type 2 diabetes ( 22158537)	Acne (severe) ( 24927181) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678)
Interacting Genes		9 interacting genes: FAM25A FAM25C FAM25G GOLM1 INCA1 MAP3K1 MTCH1 PEX5 UBC	11 interacting genes: APLNR ATP2A3 EML4 ERBB2 GSK3A KCNJ15 LGSN NQO2 PSEN1 UBC ZFAND3
Entrez ID		60685	23787
HPRD ID		12121	14787
Ensembl ID		ENSG00000156639	ENSG00000137409
Uniprot IDs		E2QRF5 Q9H8U3	A0A8Q3WKC8 A8YXX5 H0Y8C3 Q9NZJ7
PDB IDs		1X4W
Enriched GO Terms of Interacting Partners?			Heart Development Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of Muscle Hypertrophy Mechanoreceptor Activity Apelin Receptor Activity Heart Looping Embryonic Heart Tube Morphogenesis Regulation Of Cardiac Muscle Hypertrophy Apelin Receptor Signaling Pathway Negative Regulation Of Cardiac Muscle Hypertrophy Calcium-dependent ATPase Activity Calcium Ion Transport From Cytosol To Endoplasmic Reticulum Apoptotic Signaling Pathway ERBB3:ERBB2 Complex Neuromuscular Junction Negative Regulation Of Cell Development Positive Regulation Of Establishment Of Protein Localization Negative Regulation Of UDP-glucose Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Type B Pancreatic Cell Development Regulation Of Carbohydrate Catabolic Process Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Quinone Catabolic Process Melatonin Binding Oxidoreductase Activity, Acting On Other Nitrogenous Compounds As Donors Dihydronicotinamide Riboside Quinone Reductase Activity Resveratrol Binding Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cajal-Retzius Cell Differentiation Negative Regulation Of Core Promoter Binding Glutamine Synthetase Activity Glutamine Biosynthetic Process Nitrogen Utilization Positive Regulation Of G Protein-coupled Receptor Internalization RNA Polymerase I Core Binding NAD(P)H Dehydrogenase (quinone) Activity Protein Catabolic Process At Postsynapse Negative Regulation Of Transcription Regulatory Region DNA Binding Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Epithelial Tube Morphogenesis Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of L-glutamate Import Across Plasma Membrane Synaptic Vesicle Targeting Astrocyte Activation Involved In Immune Response
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