FAM3A and MS4A12

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		FAM3A	MS4A12
Description		FAM3 metabolism regulating signaling molecule A	membrane spanning 4-domains A12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Membrane
	Molecular Function	Carbohydrate Binding	Protein Binding
	Biological Process	Glucose Metabolic Process ATP Biosynthetic Process Mitochondrion Organization Response To Glucose Gene Expression Antifungal Humoral Response Insulin Secretion Calcium Ion Homeostasis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Antifungal Innate Immune Response	Cell Surface Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Eosinophil count ( 32888494) Hemoglobin levels ( 26366553) Red blood cell traits ( 23446634)	Congenital heart disease (maternal effect) ( 28468790) Lymphocyte count ( 32888494) Supramarginal gyrus volume ( 31530798)
Interacting Genes		9 interacting genes: ANP32B APP CLEC7A CREB3 MAL2 MEOX2 MS4A12 PACRGL UBC	3 interacting genes: FAM3A MALL PLLP
Entrez ID		60343	54860
HPRD ID		06505	08410
Ensembl ID		ENSG00000071889	ENSG00000071203
Uniprot IDs		D3DWX8 P98173 Q5HY75 Q9BU27	Q9NXJ0
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Superoxide Anion Generation Response To Yeast Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Superoxide Anion Generation Regulation Of Superoxide Metabolic Process Regulation Of Monocyte Chemotaxis Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Response To Calcium Ion Positive Regulation Of Calcium-mediated Signaling Amylin Binding Positive Regulation Of Toll Signaling Pathway Defense Response To Fungus Response To Fungus Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Deacetylase Activity Detection Of Yeast Detection Of Molecule Of Fungal Origin Positive Regulation Of Transport Positive Regulation Of Interleukin-1 Production Positive Regulation Of Chemokine Production Positive Regulation Of Type II Interferon Production Roof Of Mouth Development Acetylcholine Receptor Activator Activity Positive Regulation Of Mononuclear Cell Migration Regulation Of Cell Migration Positive Regulation Of Interleukin-6 Production Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Leukocyte Chemotaxis Regulation Of Calcium-mediated Signaling Lipoprotein Particle Positive Regulation Of Protein Import Detection Of Fungus (1->3)-beta-D-glucan Binding PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Chemokine Production Regulation Of Interleukin-1 Production Regulation Of Locomotion Positive Regulation Of Tumor Necrosis Factor Production Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium	Structural Constituent Of Myelin Sheath Myelination Axon Ensheathment Regulation Of Transcytosis Negative Regulation Of Antifungal Innate Immune Response Membrane Raft Compact Myelin Antifungal Humoral Response Myelin Assembly
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