RXFP1 and RLN3

Number of citations of the paper that reports this interaction (PubMedID 15649866)
0

Data Source:
HPRD (in vivo, in vitro)

		RXFP1	RLN3
Description		relaxin family peptide receptor 1	relaxin 3
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GO Annotations	Cellular Component	Plasma Membrane Membrane	Extracellular Region
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Hormone Binding Metal Ion Binding	G Protein-coupled Receptor Binding Hormone Activity Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Parturition Hormone-mediated Signaling Pathway Extracellular Matrix Organization Myofibroblast Differentiation Lung Connective Tissue Development Nipple Morphogenesis	Signal Transduction
Pathways		G alpha (s) signalling events Relaxin receptors	G alpha (s) signalling events G alpha (i) signalling events Relaxin receptors
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) Waist circumference adjusted for body mass index ( 28552196)	Obesity-related traits ( 23251661)
Interacting Genes		4 interacting genes: RLN1 RLN2 RLN3 SRPK2	4 interacting genes: ODAD3 RXFP1 RXFP3 RXFP4
Entrez ID		59350	117579
HPRD ID		05975	06031
Ensembl ID		ENSG00000171509	ENSG00000171136
Uniprot IDs		A0A087WWV0 A0A0A0MT52 B3KV27 B4DGP2 E9PCA3 Q59H16 Q9HBX9	B2RU28 K7ENX1 Q8WXF3
PDB IDs		2JM4 2M7P 7TMW	2FHW 2K1V
Enriched GO Terms of Interacting Partners?		Hormone Activity Female Pregnancy Nuclear Speck Organization R-loop Processing	Galanin Receptor Activity G Protein-coupled Receptor Activity Neuropeptide Signaling Pathway Nipple Morphogenesis G Protein-coupled Receptor Signaling Pathway Lung Connective Tissue Development Outer Dynein Arm Docking Complex Myofibroblast Differentiation Determination Of Heart Left/right Asymmetry Parturition Ciliary Rootlet Positive Regulation Of Feeding Behavior Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Cerebrospinal Fluid Circulation Hormone Binding Outer Dynein Arm Assembly Seminiferous Tubule Development Regulation Of Feeding Behavior Positive Regulation Of Behavior
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