RAB5B and SGSM3

Number of citations of the paper that reports this interaction (PubMedID 16923123)
0

Data Source:
BioGRID (two hybrid)

		RAB5B	SGSM3
Description		RAB5B, member RAS oncogene family	small G protein signaling modulator 3
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Plasma Membrane Endomembrane System Membrane Endocytic Vesicle Secretory Granule Membrane Synaptic Vesicle Membrane Early Endosome Membrane Melanosome Extracellular Exosome	Cytoplasm Cytosol Gap Junction
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding GTP-dependent Protein Binding Metal Ion Binding	GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Intracellular Protein Transport Endocytosis Endosome Organization Protein Transport Endosomal Transport Antigen Processing And Presentation Regulation Of Endocytosis Plasma Membrane To Endosome Transport	Endosomal Transport Regulation Of Endocytosis Regulation Of Rab Protein Signal Transduction Rap Protein Signal Transduction Positive Regulation Of GTPase Activity Positive Regulation Of Protein Catabolic Process Plasma Membrane To Endosome Transport Regulation Of Cell Cycle Regulation Of Cilium Assembly
Pathways		Neutrophil degranulation TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs Respiratory syncytial virus (RSV) attachment and entry
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29785011) Anorexia nervosa ( 28494655) Aspartate aminotransferase levels ( 33547301) Asthma ( 31959851 31619474 30929738) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 30929738 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) FEV1 ( 30804560) Gastroesophageal reflux disease ( 31527586) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 31928498) Lung function (FEV1) ( 30061609) Lung function (FEV1/FVC) ( 30804560) Medication use (drugs for peptic ulcer and gastro-oesophageal reflux disease) ( 31015401) Polycystic ovary syndrome ( 30566500 22885925) Refractive error ( 32231278) Sum eosinophil basophil counts ( 27863252) Type 1 diabetes ( 18198356) Vitiligo ( 22951725)	Body mass index ( 26426971) Breast size ( 29855537) Chronotype ( 27494321) Height ( 19570815) Mammographic density (dense area) ( 25342443) Morning vs. evening chronotype ( 27494321) Refractive error ( 32231278) Regular attendance at a pub or social club ( 29970889)
Interacting Genes		20 interacting genes: APOA5 CDK1 CHM EEA1 FHIP1B GLP1R HUNK PIK3CB PRIM1 RABAC1 REEP5 RIN1 RIN2 RIN3 SGSM3 SNCA SUN2 TBC1D15 TBC1D17 TFRC	10 interacting genes: CHRM3 DSCAM FMO3 GJA1 NF2 RAB39B RAB5A RAB5B RAB5C RPL35
Entrez ID		5869	27352
HPRD ID		01544	15285
Ensembl ID		ENSG00000111540	ENSG00000100359
Uniprot IDs		P61020	B4DVE3 B9A6J5 Q96HU1
PDB IDs		2HEI
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport GTPase Activator Activity Endocytosis Import Into Cell Response To Copper Ion Small GTPase Binding Hsp70 Protein Binding Regulation Of Endocytosis Endocytic Vesicle Endosome Establishment Of Localization In Cell Endosomal Transport Regulation Of Cilium Assembly Intracellular Transport Regulation Of Vesicle-mediated Transport Early Endosome To Late Endosome Transport Regulation Of Receptor-mediated Endocytosis Intracellular Signal Transduction Early Endosome Recycling Endosome Response To Iron Ion Regulation Of Cellular Component Organization Pronuclear Fusion Cellular Localization Glucagon-like Peptide 1 Receptor Activity Ribonucleotide Binding Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Mast Cell Chemotaxis Regulation Of Transport	Plasma Membrane To Endosome Transport G Protein Activity GDP Binding Endocytic Vesicle Early Endosome GTPase Activity Melanosome GTP Binding Regulation Of Transport Membrane Cell Junction Organization Regulation Of Vesicle-mediated Transport Early Endosome Membrane Endomembrane System Endosomal Transport Plasma Membrane Albendazole Monooxygenase Activity Post-embryonic Retina Morphogenesis In Camera-type Eye Regulation Of Cellular Component Organization Netrin Receptor Binding Trimethylamine Monooxygenase Activity Hypotaurine Monooxygenase Activity Regulation Of Stem Cell Proliferation Endosome Organization Positive Regulation Of Mesodermal Cell Differentiation Gap Junction Channel Activity Involved In Cardiac Conduction Electrical Coupling Schwann Cell Proliferation Ruffle Protein Localization To Early Endosome Intracellular Protein Localization Endocytosis Dendrite N,N-dimethylaniline Monooxygenase Activity Taurine Biosynthetic Process Gap Junction Channel Activity Involved In Cell Communication By Electrical Coupling Cytoplasmic Side Of Early Endosome Membrane Protein Transport Synaptic Vesicle Membrane G Protein-coupled Acetylcholine Receptor Activity Gap Junction Hemi-channel Activity Vesicle-mediated Transport Intracellular Protein Transport Saliva Secretion Positive Regulation Of Axon Extension Involved In Axon Guidance Regulation Of Secretion By Cell Acetylcholine Binding Cell-cell Signaling Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Regulation Of Secretion Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?