BBS1 and FHOD1

Number of citations of the paper that reports this interaction (PubMedID 18000879)
0

Data Source:
BioGRID (two hybrid)

		BBS1	FHOD1
Description		Bardet-Biedl syndrome 1	formin homology 2 domain containing 1
Image
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Cytoskeleton Plasma Membrane Cilium Axoneme Membrane Motile Cilium Centriolar Satellite BBSome Cell Projection Ciliary Membrane	Stress Fiber Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Intercalated Disc Membrane Bleb Cell Projection
	Molecular Function	Signaling Receptor Binding Patched Binding Smoothened Binding Protein Binding Phosphoprotein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Actin Binding Protein Binding Identical Protein Binding Actin Filament Binding
	Biological Process	Microtubule Cytoskeleton Organization Neuron Migration Retina Homeostasis Lipid Metabolic Process Visual Perception Sensory Perception Of Smell Intracellular Protein Localization Photoreceptor Cell Morphogenesis Fertilization Protein Transport Dendrite Development Ventricular System Development Striatum Development Hippocampus Development Cerebral Cortex Development Cell Projection Organization Adult Behavior Response To Endoplasmic Reticulum Stress Olfactory Behavior Hormone Metabolic Process Golgi To Plasma Membrane Protein Transport Fat Cell Differentiation Photoreceptor Cell Maintenance Brain Morphogenesis Cartilage Development Retina Development In Camera-type Eye Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Neural Precursor Cell Proliferation Protein Localization To Cilium Non-motile Cilium Assembly	Actin Filament Organization Nuclear Migration Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Stress Fiber Assembly Positive Regulation Of Stress Fiber Assembly Establishment Of Centrosome Localization
Pathways		BBSome-mediated cargo-targeting to cilium
Drugs
Diseases		Bardet-Biedl syndrome (BBS)
GWAS		Bipolar disorder ( 21926972) Height ( 28552196)	Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		19 interacting genes: ACTN3 ATP6AP2 BAD BAK1 BHMT CALCA DCTN1 EEF1A1 EIF3A EPAS1 EXOC7 FHOD1 HSCB KRT18 PARK7 PAX2 PEPD POLR2G TSPAN7	22 interacting genes: ACTA1 ACTG1 APC BBS1 BBS2 BBS4 BBS7 CR2 EXOSC8 GRB2 LNPEP NCOA6 NLGN3 PFN2 PPARG PRKG1 RAC1 RANBP2 RNF5 TRIM21 YWHAZ ZMYND8
Entrez ID		582	29109
HPRD ID		01950	06049
Ensembl ID		ENSG00000174483	ENSG00000135723
Uniprot IDs		Q8NFJ9	A0A068F7M9 Q9Y613
PDB IDs		6XT9	3DAD 6XF1 6XF2
Enriched GO Terms of Interacting Partners?		Regulation Of Mitochondrial Membrane Potential Chemical Homeostasis Homeostatic Process Cellular Homeostasis Regulation Of Programmed Cell Death Regulation Of Aerobic Respiration Cytoplasm Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Regulation Of Cellular Respiration Cytosol Epithelial Cell Proliferation Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Programmed Cell Death Release Of Cytochrome C From Mitochondria Mitochondrion Organization Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Autophagy Positive Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Protein Metabolic Process Intracellular Chemical Homeostasis Regulation Of Calcium Ion Transport Into Cytosol Blood Vessel Remodeling Regulation Of Homocysteine Metabolic Process 'de Novo' L-methionine Biosynthetic Process Axon Nucleus Localization Nuclear Migration Centriolar Satellite Microtubule Organizing Center Negative Regulation Of Reactive Oxygen Species Metabolic Process Optic Chiasma Development Positive Regulation Of Optic Nerve Formation Proline Dipeptidase Activity Eye Pigmentation Glyoxal Catabolic Process L-dopa Decarboxylase Activator Activity Guanine Deglycation Protein Deglycase Activity Glyoxalase (glycolic Acid-forming) Activity Glycolate Biosynthetic Process Guanine Deglycation, Methylglyoxal Removal Guanine Deglycation, Glyoxal Removal Detoxification Of Mercury Ion Negative Regulation Of Death-inducing Signaling Complex Assembly Cellular Response To Glyoxal Glyoxal Metabolic Process Positive Regulation Of L-dopa Biosynthetic Process Tyrosine 3-monooxygenase Activator Activity	BBSome Regulation Of Cell Motility Regulation Of Locomotion Dendrite Development Regulation Of Biological Quality Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Negative Regulation Of Immune Response Negative Regulation Of Innate Immune Response Regulation Of Microtubule-based Movement Non-motile Cilium Assembly Fat Cell Differentiation Ciliary Membrane Regulation Of Organelle Organization Regulation Of Metabolic Process Striatum Development Regulation Of Cilium Beat Frequency Positive Regulation Of Cellular Component Biogenesis Brain Morphogenesis Melanosome Transport Establishment Of Melanosome Localization Pigment Granule Transport Melanosome Localization Pigment Granule Localization Regulation Of Stress Fiber Assembly Regulation Of Supramolecular Fiber Organization Regulation Of Cell Projection Assembly Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Cytosol Regulation Of Cilium Movement Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Regulation Of Actin Filament Organization Cytoskeleton Organization Regulation Of Microtubule-based Process Photoreceptor Cell Maintenance Regulation Of Actin Filament Polymerization Centriolar Satellite Negative Regulation Of Defense Response Neuron Migration Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Actin Filament Polymerization Adult Behavior Cytoskeleton Regulation Of Cytoskeleton Organization Negative Regulation Of Metabolic Process Negative Regulation Of Immune System Process Negative Regulation Of Cell Migration Cellular Developmental Process Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Cell Motility
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