SLAMF7 and MAK

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		SLAMF7	MAK
Description		SLAM family member 7	male germ cell associated kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane	Photoreceptor Outer Segment Photoreceptor Inner Segment Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Plasma Membrane Cilium Axoneme Midbody Motile Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Cell Projection Mitotic Spindle
	Molecular Function	Identical Protein Binding	Nucleotide Binding Transcription Coactivator Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Adaptive Immune Response Immune System Process Immune Response Cell Adhesion Natural Killer Cell Activation T Cell Activation Natural Killer Cell Mediated Cytotoxicity Innate Immune Response	Protein Phosphorylation Spermatogenesis Cell Differentiation Intracellular Signal Transduction Intraciliary Transport Photoreceptor Cell Maintenance Positive Regulation Of DNA-templated Transcription Protein Autophosphorylation Cilium Assembly Negative Regulation Of Non-motile Cilium Assembly Non-motile Cilium Assembly
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Elotuzumab
Diseases
GWAS		Blood protein levels ( 30072576) IgM levels ( 28628107) Inflammatory bowel disease ( 23128233) Microalbuminuria ( 26631737) Multiple sclerosis ( 24076602)	Menopause (age at onset) ( 26414677) Recurrent major depressive disorder ( 29317602) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		11 interacting genes: ADRA2A API5 CLK3 MAK PANK1 PITX2 SH2D1A SVIL THRSP TMOD4 TRIB2	9 interacting genes: ANAPC11 APP FBXO7 FZR1 NDUFB7 PPP2CB SERINC1 SLAMF7 SND1
Entrez ID		57823	4117
HPRD ID		09432	01101
Ensembl ID		ENSG00000026751	ENSG00000111837
Uniprot IDs		B4DVL7 B4DW98 Q9NQ25	A0A140VK28 A0A6Q8PG01 A0A6Q8PH30 F8VBW7 P20794 Q8IXN4
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasm Negative Regulation Of Uterine Smooth Muscle Contraction Alpha-1B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Phospholipase C-activating Adrenergic Receptor Signaling Pathway Protein Homodimerization Activity Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Protein Phosphorylation Negative Regulation Of Non-motile Cilium Assembly Skeletal Muscle Tissue Development Left Lung Morphogenesis Superior Vena Cava Morphogenesis Prolactin Secreting Cell Differentiation Cell Proliferation Involved In Outflow Tract Morphogenesis Pulmonary Vein Morphogenesis Subthalamic Nucleus Development Regulation Of Actin Filament Depolymerization Actin Filament Capping Negative Regulation Of Protein-containing Complex Disassembly Negative Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Pantothenate Kinase Activity Regulation Of Protein Depolymerization Actin Filament-based Process Alpha2-adrenergic Receptor Activity Phosphorylation Pulmonary Myocardium Development Endodermal Digestive Tract Morphogenesis Deltoid Tuberosity Development Norepinephrine Binding Thermoception Somatotropin Secreting Cell Differentiation Cell Proliferation Involved In Heart Morphogenesis Acetyl-CoA Binding Negative Regulation Of Norepinephrine Secretion Epinephrine Binding Negative Regulation Of Epinephrine Secretion Protein Kinase Activity Striated Muscle Tissue Development Embryonic Heart Tube Left/right Pattern Formation Muscle Structure Development Extraocular Skeletal Muscle Development Atrioventricular Valve Development Regulation Of Actin Filament Polymerization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Protein-containing Complex Disassembly Negative Regulation Of Protein-containing Complex Assembly Ubiquitin-protein Transferase Regulator Activity Pointed-end Actin Filament Capping	Response To Lead Ion Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Anaphase-promoting Complex-dependent Catabolic Process Anaphase-promoting Complex Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein Catabolic Process Protein K11-linked Ubiquitination Proteolysis Involved In Protein Catabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Polyubiquitination Regulation Of Cell Cycle Process Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite RNAi Effector Complex Regulation Of Meiotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition G Protein-coupled Receptor Binding Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Catabolic Process Ubiquitin-like Ligase-substrate Adaptor Activity Lewy Body Core Protein K48-linked Ubiquitination Regulation Of Cell Cycle Phase Transition DNA Synthesis Involved In Mitotic DNA Replication Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Catabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?