HOMEZ and ANKRD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HOMEZ	ANKRD2
Description		homeobox and leucine zipper encoding	ankyrin repeat domain 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol	Euchromatin Nucleus Cytoplasm Cytosol PML Body I Band
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding	Protein Binding Structural Constituent Of Muscle Protein Kinase B Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Muscle Contraction Muscle Organ Development Regulation Of Gene Expression Negative Regulation Of Myoblast Differentiation
Pathways
Drugs
Diseases
GWAS		Height ( 31562340) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Mean platelet volume ( 32888494) Pulse pressure ( 27841878) Reticulocyte count ( 32888494) Serum alkaline phosphatase levels ( 33547301) Systolic blood pressure ( 27841878)
Interacting Genes		114 interacting genes: ACTR10 AEN ANKRD11 ANKRD2 ARHGAP9 ASB6 AXIN1 BIVM BYSL C2orf42 CBX8 CCDC13 CCDC187 CCHCR1 CCNK CDC7 CENPS CENPS-CORT CFAP206 CTNNA3 DEF6 DGCR6 DHX16 DNTTIP1 DRC4 EBF1 EIF4E2 ELOA ENKD1 FAM90A1 FARS2 GFAP GPANK1 GRB2 HOXC8 HSF2BP IL16 INO80B JAKMIP2 KIFC3 KPNA2 LENG1 LGALS4 LMO1 LMO3 LNX1 LRRC7 LSM4 MAD2L1BP MAFG MAPK1 MED18 MORF4L2 MOS MRPL11 NCK1 NCK2 NEIL2 NEK6 NXF1 OSGIN1 PARVG PHF1 PHF19 PIBF1 PIN1 PLEKHA7 POLDIP3 PRKAA1 PRKAA2 PRPF18 PSMA1 RASL10A RBM39 RNF8 RPGR RPL9 RPP25 RPS25 SCNM1 SDCBP SEC23A SH3RF2 SMARCB1 SMARCD1 SMYD1 SNRPB2 SUMO2 SUMO3 TARS2 TBC1D30 TCEA2 TCEANC TEAD4 TLE5 TRAF4 TSGA10IP TXK USF1 VEZF1 VPS9D1 ZBTB25 ZBTB7A ZMYND19 ZNF165 ZNF250 ZNF280C ZNF35 ZNF417 ZNF580 ZNF629 ZNF688 ZNF76 ZSCAN5B	11 interacting genes: FCMR HBP1 HOMEZ LDB3 MAPK6 PML TCAP TP53 TTN YBX1 ZBTB3
Entrez ID		57594	26287
HPRD ID		12167	12460
Ensembl ID		ENSG00000290292	ENSG00000165887
Uniprot IDs		Q8IX15	A0A0A0MRN9 Q5T457 Q9GZV1
PDB IDs		2ECC 2YS9
Enriched GO Terms of Interacting Partners?		Nucleus Nucleoplasm Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Ciliary Basal Body Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Histone H2BS36 Kinase Activity [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity Regulation Of Metabolic Process Nucleic Acid Metabolic Process Zinc Ion Binding Nuclear Speck Zonula Adherens Maintenance Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Protein Localization To Lipid Droplet Microtubule Cytoskeleton Positive Regulation Of DNA Repair Centrosome Cytoskeletal Anchor Activity Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress DNA Binding Cellular Response To Stress Adherens Junction Maintenance Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Tubulin Deacetylation Negative Regulation Of Hepatocyte Apoptotic Process AMP-activated Protein Kinase Activity Positive Regulation Of DNA Metabolic Process Protein K6-linked Ubiquitination Regulation Of DNA-templated Transcription Elongation DNA Damage Response Regulation Of Translational Initiation Regulation Of Sister Chromatid Segregation Microtubule Cytoskeleton Organization Positive Regulation Of Translation In Response To Stress Histone H3K36me3 Reader Activity Regulation Of Tubulin Deacetylation Lipid Droplet Disassembly Macromolecule Metabolic Process Nucleobase-containing Compound Metabolic Process	Titin-telethonin Complex Sarcomerogenesis Skeletal Muscle Myosin Thick Filament Assembly Myosin Filament Assembly Sarcomere Organization Skeletal Muscle Thin Filament Assembly Detection Of Muscle Stretch Muscle Alpha-actinin Binding Cardiac Myofibril Assembly Muscle Filament Sliding Actomyosin Structure Organization Actin-myosin Filament Sliding Negative Regulation Of Telomere Maintenance Via Telomerase Z Disc Entrainment Of Circadian Clock By Photoperiod Cardiac Muscle Hypertrophy Response To Muscle Stretch I Band Photoperiodism Entrainment Of Circadian Clock Muscle Hypertrophy Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Myofibril Assembly Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Skeletal Muscle Contraction Negative Regulation Of Telomere Maintenance Actin-mediated Cell Contraction Cardiac Muscle Cell Development Regulation Of Telomere Maintenance Via Telomerase Structural Constituent Of Muscle Cardiac Muscle Contraction Cardiac Cell Development Detection Of Mechanical Stimulus Somitogenesis DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cellular Senescence Regulation Of Telomere Maintenance Via Telomere Lengthening Response To Gamma Radiation Segmentation Negative Regulation Of Translation In Response To Oxidative Stress Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Heart Development Cardiac Muscle Tissue Morphogenesis High-affinity IgM Receptor Activity Actin Filament-based Movement Cellular Senescence
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?